FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164275372> ?p ?o ?g. }

• W2164275372 endingPage "10" @default.
• W2164275372 startingPage "1" @default.
• W2164275372 abstract "Following peripheral axotomy, the presynaptic terminals are removed from lesioned neurons, that is synaptic stripping. To elucidate involvement of astrocytes and microglia in synaptic stripping, we herein examined the motoneuron perineuronal circumference after hypoglossal nerve transection. As reported previously, axotomy-induced slow cell death occurred in C57BL/6 mice but not in Wistar rats. Synaptophysin labeling in the hypoglossal nucleus exhibited a minor reduction in both species after axotomy. Slice patch recording showed that the mean frequency of miniature postsynaptic currents in axotomized motoneurons was significantly lower in rats than in mice. We then estimated the relative coverage of motoneuron perineuronal circumference by line profile analysis. In the synaptic environment, axotomy-induced intrusion of astrocytic processes was significantly more extensive in rats than in mice, whereas microglial intrusion into the synaptic space was significantly more severe in mice than in rats. Interestingly, in the extrasynaptic environment, the prevalence of contact between astrocytic processes and lesioned motoneurons was significantly increased in rats, while no significant axotomy-induced alterations in astrocytic contact were observed in mice. These findings indicate that astrocytic, but not microglial, reaction may primarily mediate some anti-apoptotic effects through synaptic stripping after hypoglossal nerve axotomy. In addition, enlargement of astrocytic processes in the extrasynaptic environment may also be involved in neuronal protection via the increased uptake of excessive glutamate." @default.
• W2164275372 created "2016-06-24" @default.
• W2164275372 creator A5003217112 @default.
• W2164275372 creator A5008164044 @default.
• W2164275372 creator A5090640616 @default.
• W2164275372 date "2011-05-01" @default.
• W2164275372 modified "2023-10-07" @default.
• W2164275372 title "Differential involvement of perineuronal astrocytes and microglia in synaptic stripping after hypoglossal axotomy" @default.
• W2164275372 cites W1535641516 @default.
• W2164275372 cites W1898526558 @default.
• W2164275372 cites W1964156456 @default.
• W2164275372 cites W1965493535 @default.
• W2164275372 cites W1971668430 @default.
• W2164275372 cites W1973361488 @default.
• W2164275372 cites W1981253817 @default.
• W2164275372 cites W1986655894 @default.
• W2164275372 cites W2002789216 @default.
• W2164275372 cites W2007811903 @default.
• W2164275372 cites W2013709298 @default.
• W2164275372 cites W2015949591 @default.
• W2164275372 cites W2017364016 @default.
• W2164275372 cites W2019454304 @default.
• W2164275372 cites W2020138925 @default.
• W2164275372 cites W2033966441 @default.
• W2164275372 cites W2042930560 @default.
• W2164275372 cites W2048152346 @default.
• W2164275372 cites W2053063069 @default.
• W2164275372 cites W2057258185 @default.
• W2164275372 cites W2059714868 @default.
• W2164275372 cites W2068086018 @default.
• W2164275372 cites W2071369096 @default.
• W2164275372 cites W2077070290 @default.
• W2164275372 cites W2079672852 @default.
• W2164275372 cites W2081070804 @default.
• W2164275372 cites W2082178034 @default.
• W2164275372 cites W2082351110 @default.
• W2164275372 cites W2082789085 @default.
• W2164275372 cites W2087057470 @default.
• W2164275372 cites W2092985749 @default.
• W2164275372 cites W2094660330 @default.
• W2164275372 cites W2104417933 @default.
• W2164275372 cites W2109759840 @default.
• W2164275372 cites W2111565211 @default.
• W2164275372 cites W2111995151 @default.
• W2164275372 cites W2113107925 @default.
• W2164275372 cites W2116605894 @default.
• W2164275372 cites W2121396070 @default.
• W2164275372 cites W2122804584 @default.
• W2164275372 cites W2122828560 @default.
• W2164275372 cites W2164191009 @default.
• W2164275372 cites W2165068449 @default.
• W2164275372 cites W2165721042 @default.
• W2164275372 cites W3188111987 @default.
• W2164275372 cites W2089680592 @default.
• W2164275372 doi "https://doi.org/10.1016/j.neuroscience.2011.03.030" @default.
• W2164275372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21435379" @default.
• W2164275372 hasPublicationYear "2011" @default.
• W2164275372 type Work @default.
• W2164275372 sameAs 2164275372 @default.
• W2164275372 citedByCount "43" @default.
• W2164275372 countsByYear W21642753722012 @default.
• W2164275372 countsByYear W21642753722013 @default.
• W2164275372 countsByYear W21642753722014 @default.
• W2164275372 countsByYear W21642753722015 @default.
• W2164275372 countsByYear W21642753722016 @default.
• W2164275372 countsByYear W21642753722017 @default.
• W2164275372 countsByYear W21642753722018 @default.
• W2164275372 countsByYear W21642753722019 @default.
• W2164275372 countsByYear W21642753722020 @default.
• W2164275372 countsByYear W21642753722021 @default.
• W2164275372 countsByYear W21642753722022 @default.
• W2164275372 countsByYear W21642753722023 @default.
• W2164275372 crossrefType "journal-article" @default.
• W2164275372 hasAuthorship W2164275372A5003217112 @default.
• W2164275372 hasAuthorship W2164275372A5008164044 @default.
• W2164275372 hasAuthorship W2164275372A5090640616 @default.
• W2164275372 hasConcept C142724271 @default.
• W2164275372 hasConcept C169760540 @default.
• W2164275372 hasConcept C170493617 @default.
• W2164275372 hasConcept C185592680 @default.
• W2164275372 hasConcept C197341189 @default.
• W2164275372 hasConcept C203014093 @default.
• W2164275372 hasConcept C2776914184 @default.
• W2164275372 hasConcept C2779209236 @default.
• W2164275372 hasConcept C2779683492 @default.
• W2164275372 hasConcept C2779744641 @default.
• W2164275372 hasConcept C2779830541 @default.
• W2164275372 hasConcept C2781333164 @default.
• W2164275372 hasConcept C529278444 @default.
• W2164275372 hasConcept C55493867 @default.
• W2164275372 hasConcept C71924100 @default.
• W2164275372 hasConcept C86803240 @default.
• W2164275372 hasConceptScore W2164275372C142724271 @default.
• W2164275372 hasConceptScore W2164275372C169760540 @default.
• W2164275372 hasConceptScore W2164275372C170493617 @default.
• W2164275372 hasConceptScore W2164275372C185592680 @default.
• W2164275372 hasConceptScore W2164275372C197341189 @default.
• W2164275372 hasConceptScore W2164275372C203014093 @default.

• next