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• W2164312633 abstract "This paper describes a simple chiral primary amine-catalyzed highly efficient and practical protocol for the synthesis of both Wieland–Miescher ketone and Hajos–Parrish ketone as well as their analogues. The reaction can be conducted in gram scale with 1% mol catalyst loading producing high enantioselectivity (up to 96% ee) and excellent yields (up to 98%). This procedure represents one of the most efficient methods for the synthesis of these versatile chiral building blocks." @default.
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• W2164312633 date "2012-02-14" @default.
• W2164312633 modified "2023-10-18" @default.
• W2164312633 title "Asymmetric Synthesis of Wieland–Miescher and Hajos–Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine" @default.
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• W2164312633 doi "https://doi.org/10.1021/jo202433v" @default.
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