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- W2164341793 abstract "Constrained ceramide analogs were designed and synthesized by binding terminal alcohol and amine of ceramide with additional carbonyl functional group as 3-acetyl (3), 3-propionyl (4), 3-benzoyl (5), and 3-hexadecanoyl-4-(1-hydroxyhexadec-2-enyl)-oxazolidin-2-ones (6). Compounds 4 and 5 showed potent antileukemic activities against human leukemia HL-60 cells with good correlation between cell death and DNA fragmentation." @default.
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- W2164341793 date "2006-04-01" @default.
- W2164341793 modified "2023-10-16" @default.
- W2164341793 title "Synthesis of constrained ceramide analogs and their potent antileukemic activities" @default.
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- W2164341793 doi "https://doi.org/10.1016/j.bmcl.2005.12.091" @default.
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