Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164354906> ?p ?o ?g. }
- W2164354906 endingPage "1691" @default.
- W2164354906 startingPage "1683" @default.
- W2164354906 abstract "Human serum albumin nonenzymatically condenses with glucose to form stable Amadori adducts that are increased with the hyperglycemia of diabetes. The present study evaluated the influence of fatty acids, which are major endogenous ligands, on albumin glycation and of glycation on albumin conformation and exogenous ligand binding. Physiologic concentrations of palmitate, oleate, and linoleate reduced the ability of albumin to form glucose adducts, whereas glycation decreased intrinsic fluorescence, lowered the affinity for dansylsarcosine, and diminished the fatty acid-induced increase in limiting fluorescence of protein-bound warfarin that was observed with nonglycated albumin. The findings indicate that fatty acids impede the ability of albumin to undergo Amadori glucose modification and induce conformational changes affecting exogenous ligand binding, and that nonenzymatic glycation of albumin induces alterations in structural and functional properties that may have import in lipid transport and atherogenesis." @default.
- W2164354906 created "2016-06-24" @default.
- W2164354906 creator A5011765487 @default.
- W2164354906 creator A5016697136 @default.
- W2164354906 creator A5028478639 @default.
- W2164354906 creator A5067055578 @default.
- W2164354906 date "2011-12-01" @default.
- W2164354906 modified "2023-09-30" @default.
- W2164354906 title "Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin" @default.
- W2164354906 cites W1499495082 @default.
- W2164354906 cites W1562673459 @default.
- W2164354906 cites W1575563617 @default.
- W2164354906 cites W1582388915 @default.
- W2164354906 cites W1749195494 @default.
- W2164354906 cites W1792162018 @default.
- W2164354906 cites W1904977455 @default.
- W2164354906 cites W1964419367 @default.
- W2164354906 cites W1964900539 @default.
- W2164354906 cites W1977892627 @default.
- W2164354906 cites W1989595554 @default.
- W2164354906 cites W1990806982 @default.
- W2164354906 cites W1991423922 @default.
- W2164354906 cites W2012769886 @default.
- W2164354906 cites W2013633841 @default.
- W2164354906 cites W2016401253 @default.
- W2164354906 cites W2017654147 @default.
- W2164354906 cites W2022137963 @default.
- W2164354906 cites W2031085640 @default.
- W2164354906 cites W2047867647 @default.
- W2164354906 cites W2049071218 @default.
- W2164354906 cites W2049794880 @default.
- W2164354906 cites W2057107933 @default.
- W2164354906 cites W2067713279 @default.
- W2164354906 cites W2075961139 @default.
- W2164354906 cites W2087649643 @default.
- W2164354906 cites W2088900329 @default.
- W2164354906 cites W2090427843 @default.
- W2164354906 cites W2116919836 @default.
- W2164354906 cites W2118531564 @default.
- W2164354906 cites W2144621833 @default.
- W2164354906 cites W2152604288 @default.
- W2164354906 cites W2161566403 @default.
- W2164354906 cites W2168027703 @default.
- W2164354906 cites W217420229 @default.
- W2164354906 cites W2186752877 @default.
- W2164354906 cites W2188225019 @default.
- W2164354906 cites W2312856423 @default.
- W2164354906 doi "https://doi.org/10.1016/j.metabol.2011.03.022" @default.
- W2164354906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21632076" @default.
- W2164354906 hasPublicationYear "2011" @default.
- W2164354906 type Work @default.
- W2164354906 sameAs 2164354906 @default.
- W2164354906 citedByCount "10" @default.
- W2164354906 countsByYear W21643549062012 @default.
- W2164354906 countsByYear W21643549062013 @default.
- W2164354906 countsByYear W21643549062014 @default.
- W2164354906 countsByYear W21643549062018 @default.
- W2164354906 countsByYear W21643549062023 @default.
- W2164354906 crossrefType "journal-article" @default.
- W2164354906 hasAuthorship W2164354906A5011765487 @default.
- W2164354906 hasAuthorship W2164354906A5016697136 @default.
- W2164354906 hasAuthorship W2164354906A5028478639 @default.
- W2164354906 hasAuthorship W2164354906A5067055578 @default.
- W2164354906 hasConcept C118094880 @default.
- W2164354906 hasConcept C147990577 @default.
- W2164354906 hasConcept C165616093 @default.
- W2164354906 hasConcept C170493617 @default.
- W2164354906 hasConcept C185592680 @default.
- W2164354906 hasConcept C2776125364 @default.
- W2164354906 hasConcept C2778597219 @default.
- W2164354906 hasConcept C543025807 @default.
- W2164354906 hasConcept C55493867 @default.
- W2164354906 hasConceptScore W2164354906C118094880 @default.
- W2164354906 hasConceptScore W2164354906C147990577 @default.
- W2164354906 hasConceptScore W2164354906C165616093 @default.
- W2164354906 hasConceptScore W2164354906C170493617 @default.
- W2164354906 hasConceptScore W2164354906C185592680 @default.
- W2164354906 hasConceptScore W2164354906C2776125364 @default.
- W2164354906 hasConceptScore W2164354906C2778597219 @default.
- W2164354906 hasConceptScore W2164354906C543025807 @default.
- W2164354906 hasConceptScore W2164354906C55493867 @default.
- W2164354906 hasIssue "12" @default.
- W2164354906 hasLocation W21643549061 @default.
- W2164354906 hasLocation W21643549062 @default.
- W2164354906 hasOpenAccess W2164354906 @default.
- W2164354906 hasPrimaryLocation W21643549061 @default.
- W2164354906 hasRelatedWork W1997155892 @default.
- W2164354906 hasRelatedWork W2000937688 @default.
- W2164354906 hasRelatedWork W2008029414 @default.
- W2164354906 hasRelatedWork W2065311899 @default.
- W2164354906 hasRelatedWork W2164354906 @default.
- W2164354906 hasRelatedWork W2487229662 @default.
- W2164354906 hasRelatedWork W2589020858 @default.
- W2164354906 hasRelatedWork W2749117048 @default.
- W2164354906 hasRelatedWork W2908104479 @default.
- W2164354906 hasRelatedWork W297042233 @default.
- W2164354906 hasVolume "60" @default.
- W2164354906 isParatext "false" @default.