Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164597170> ?p ?o ?g. }
- W2164597170 endingPage "H556" @default.
- W2164597170 startingPage "H549" @default.
- W2164597170 abstract "Although Src protein tyrosine kinases (PTKs) have been shown to be essential in late preconditioning (PC) against myocardial stunning, their role in triggering versus mediating late PC against myocardial infarction remains unclear. Four groups of conscious rabbits were subjected to a 30-min coronary occlusion on day 2, with or without PC ischemia on day 1. Administration of the Src PTK inhibitor lavendustin A (LD-A; 1 mg/kg iv) before the PC ischemia on day 1 (group III, n = 7) failed to block the delayed protective effect against myocardial infarction 24 h later. Late PC against infarction, however, was completely abrogated when LD-A was given 24 h after the PC ischemia, prior to the 30-min occlusion on day 2 (group IV, n = 8). We conclude that, in conscious rabbits, Src PTK activity is necessary for the mediation of late PC protection against myocardial infarction on day 2, but not for the initiation of this phenomenon on day 1. Taken together with previous studies in the setting of stunning, these findings reveal heretofore unrecognized differences in the roles of Src PTKs in late PC against stunning versus late PC against infarction." @default.
- W2164597170 created "2016-06-24" @default.
- W2164597170 creator A5000397083 @default.
- W2164597170 creator A5008671980 @default.
- W2164597170 creator A5019563599 @default.
- W2164597170 creator A5029768980 @default.
- W2164597170 creator A5044326141 @default.
- W2164597170 creator A5058527965 @default.
- W2164597170 creator A5078398693 @default.
- W2164597170 creator A5083442694 @default.
- W2164597170 date "2002-08-01" @default.
- W2164597170 modified "2023-10-12" @default.
- W2164597170 title "Role of Src protein tyrosine kinases in late preconditioning against myocardial infarction" @default.
- W2164597170 cites W171049546 @default.
- W2164597170 cites W1814497677 @default.
- W2164597170 cites W1820680275 @default.
- W2164597170 cites W1964972368 @default.
- W2164597170 cites W1967526945 @default.
- W2164597170 cites W1969303336 @default.
- W2164597170 cites W1972869034 @default.
- W2164597170 cites W1979250205 @default.
- W2164597170 cites W1986382066 @default.
- W2164597170 cites W1991838517 @default.
- W2164597170 cites W2000400143 @default.
- W2164597170 cites W2009777524 @default.
- W2164597170 cites W2021612538 @default.
- W2164597170 cites W2024393365 @default.
- W2164597170 cites W2049133393 @default.
- W2164597170 cites W2055276390 @default.
- W2164597170 cites W2060120053 @default.
- W2164597170 cites W2072256028 @default.
- W2164597170 cites W2079097756 @default.
- W2164597170 cites W2080335295 @default.
- W2164597170 cites W2099512945 @default.
- W2164597170 cites W2100065656 @default.
- W2164597170 cites W2110204147 @default.
- W2164597170 cites W2110678149 @default.
- W2164597170 cites W2110759870 @default.
- W2164597170 cites W2117594247 @default.
- W2164597170 cites W2127186576 @default.
- W2164597170 cites W2129855301 @default.
- W2164597170 cites W2132494613 @default.
- W2164597170 cites W2133193775 @default.
- W2164597170 cites W2160696128 @default.
- W2164597170 cites W2161074774 @default.
- W2164597170 cites W2180005201 @default.
- W2164597170 cites W2398705183 @default.
- W2164597170 cites W2408352480 @default.
- W2164597170 cites W4234087973 @default.
- W2164597170 doi "https://doi.org/10.1152/ajpheart.00873.2001" @default.
- W2164597170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12124200" @default.
- W2164597170 hasPublicationYear "2002" @default.
- W2164597170 type Work @default.
- W2164597170 sameAs 2164597170 @default.
- W2164597170 citedByCount "11" @default.
- W2164597170 countsByYear W21645971702012 @default.
- W2164597170 countsByYear W21645971702017 @default.
- W2164597170 crossrefType "journal-article" @default.
- W2164597170 hasAuthorship W2164597170A5000397083 @default.
- W2164597170 hasAuthorship W2164597170A5008671980 @default.
- W2164597170 hasAuthorship W2164597170A5019563599 @default.
- W2164597170 hasAuthorship W2164597170A5029768980 @default.
- W2164597170 hasAuthorship W2164597170A5044326141 @default.
- W2164597170 hasAuthorship W2164597170A5058527965 @default.
- W2164597170 hasAuthorship W2164597170A5078398693 @default.
- W2164597170 hasAuthorship W2164597170A5083442694 @default.
- W2164597170 hasConcept C108636557 @default.
- W2164597170 hasConcept C126322002 @default.
- W2164597170 hasConcept C134018914 @default.
- W2164597170 hasConcept C164705383 @default.
- W2164597170 hasConcept C170493617 @default.
- W2164597170 hasConcept C2775992611 @default.
- W2164597170 hasConcept C2776268601 @default.
- W2164597170 hasConcept C2777798775 @default.
- W2164597170 hasConcept C2778492669 @default.
- W2164597170 hasConcept C2779311647 @default.
- W2164597170 hasConcept C2780393670 @default.
- W2164597170 hasConcept C42362537 @default.
- W2164597170 hasConcept C500558357 @default.
- W2164597170 hasConcept C541997718 @default.
- W2164597170 hasConcept C71924100 @default.
- W2164597170 hasConceptScore W2164597170C108636557 @default.
- W2164597170 hasConceptScore W2164597170C126322002 @default.
- W2164597170 hasConceptScore W2164597170C134018914 @default.
- W2164597170 hasConceptScore W2164597170C164705383 @default.
- W2164597170 hasConceptScore W2164597170C170493617 @default.
- W2164597170 hasConceptScore W2164597170C2775992611 @default.
- W2164597170 hasConceptScore W2164597170C2776268601 @default.
- W2164597170 hasConceptScore W2164597170C2777798775 @default.
- W2164597170 hasConceptScore W2164597170C2778492669 @default.
- W2164597170 hasConceptScore W2164597170C2779311647 @default.
- W2164597170 hasConceptScore W2164597170C2780393670 @default.
- W2164597170 hasConceptScore W2164597170C42362537 @default.
- W2164597170 hasConceptScore W2164597170C500558357 @default.
- W2164597170 hasConceptScore W2164597170C541997718 @default.
- W2164597170 hasConceptScore W2164597170C71924100 @default.
- W2164597170 hasIssue "2" @default.
- W2164597170 hasLocation W21645971701 @default.