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- W2164620932 abstract "Objective: To better understand the impact of genetics on resilience and successful aging, we tested a model of successful aging. Method: This was a descriptive study with a single interview and blood draw done with residents in a continuing care retirement community. Five genes associated with resilience were included in the model. The hypothesis was tested using structural equation modeling. Results: A total of 116 participants completed the survey. Two SNPs from SLC6A4 (rs25533 and rs1042173) and age were the only variables associated with physical resilience and explained 9% of the variance. Cognitive status, age, and depression were directly associated with successful aging; variance in rs25532 or rs1042173, resilience, and pain were indirectly associated with successful aging through depression. Discussion: Continued research to replicate these findings is needed so as to be able to recognize older adults at risk of low physical resilience and implement appropriate interventions." @default.
- W2164620932 created "2016-06-24" @default.
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- W2164620932 date "2015-03-27" @default.
- W2164620932 modified "2023-10-16" @default.
- W2164620932 title "The Impact of Genetics on Physical Resilience and Successful Aging" @default.
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- W2164620932 doi "https://doi.org/10.1177/0898264315577586" @default.
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