Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164672022> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2164672022 abstract "Chronic obstructive pulmonary disease patients, especially those with emphysema, show steep slopes of the alveolar plateau (S). This study tested the hypothesis that continued gas exchange between poorly and well-ventilated lung units by means of collateral ventilation would contribute to S in these patients. Nine young volunteers, nine older volunteers and 11 patients with macroscopic emphysema performed wash-out tests with helium (He) and sulphur hexafluoride (SF6). S was determined for breaths 1-5 (range 1), and for breaths between 95% and 98% of complete wash-out (range 2). An unequal ventilation index (UVI) was defined as the ratio between the estimated mean alveolar pressure and the end tidal pressure (PET) of each tracer gas, calculated over range 2. Over the same range, a phase III ratio was calculated by dividing PET by the estimated pressure at Fowler dead space. In all groups of subjects, the S for He and SF6 were greater for range 2 than for range 1 (p< or =0.012). In the emphysema patients, the correlations between S and UVI were 0.72 for He (p=0.012) and 0.81 for SF6 (p=0.002), while the mean phase III ratios were 1.7 for He and 2.4 for SF6, much less than their theoretical maxima. It was concluded that in patients collateral ventilation may account for only a small part of the increase in the alveolar plateau slope between ranges 1 and 2, and that this increase was mainly caused by unequal ventilation in combination with sequential emptying of lung units. The degree of sequential emptying, however, was modest compared with its full potential." @default.
- W2164672022 created "2016-06-24" @default.
- W2164672022 creator A5022166539 @default.
- W2164672022 creator A5031539199 @default.
- W2164672022 creator A5050530688 @default.
- W2164672022 creator A5062699123 @default.
- W2164672022 creator A5066196943 @default.
- W2164672022 date "1999-07-01" @default.
- W2164672022 modified "2023-10-16" @default.
- W2164672022 title "Intrapulmonary gas mixing and the sloping alveolar plateau in COPD patients with macroscopic emphysema" @default.
- W2164672022 cites W1757725632 @default.
- W2164672022 cites W2017350059 @default.
- W2164672022 cites W2029069060 @default.
- W2164672022 cites W2059573911 @default.
- W2164672022 cites W2071314120 @default.
- W2164672022 cites W2072415850 @default.
- W2164672022 cites W2090441655 @default.
- W2164672022 cites W2117494756 @default.
- W2164672022 cites W2175247111 @default.
- W2164672022 cites W2252935822 @default.
- W2164672022 cites W25643295 @default.
- W2164672022 cites W2994597783 @default.
- W2164672022 cites W2413900486 @default.
- W2164672022 doi "https://doi.org/10.1034/j.1399-3003.1999.14a28.x" @default.
- W2164672022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10489846" @default.
- W2164672022 hasPublicationYear "1999" @default.
- W2164672022 type Work @default.
- W2164672022 sameAs 2164672022 @default.
- W2164672022 citedByCount "7" @default.
- W2164672022 countsByYear W21646720222013 @default.
- W2164672022 countsByYear W21646720222014 @default.
- W2164672022 countsByYear W21646720222016 @default.
- W2164672022 crossrefType "journal-article" @default.
- W2164672022 hasAuthorship W2164672022A5022166539 @default.
- W2164672022 hasAuthorship W2164672022A5031539199 @default.
- W2164672022 hasAuthorship W2164672022A5050530688 @default.
- W2164672022 hasAuthorship W2164672022A5062699123 @default.
- W2164672022 hasAuthorship W2164672022A5066196943 @default.
- W2164672022 hasConcept C121332964 @default.
- W2164672022 hasConcept C126322002 @default.
- W2164672022 hasConcept C134306372 @default.
- W2164672022 hasConcept C153294291 @default.
- W2164672022 hasConcept C164705383 @default.
- W2164672022 hasConcept C200457457 @default.
- W2164672022 hasConcept C2776780178 @default.
- W2164672022 hasConcept C2777080012 @default.
- W2164672022 hasConcept C2777257755 @default.
- W2164672022 hasConcept C2777311218 @default.
- W2164672022 hasConcept C2777714996 @default.
- W2164672022 hasConcept C2777944223 @default.
- W2164672022 hasConcept C2778917391 @default.
- W2164672022 hasConcept C2780030769 @default.
- W2164672022 hasConcept C2989005 @default.
- W2164672022 hasConcept C2992779976 @default.
- W2164672022 hasConcept C33923547 @default.
- W2164672022 hasConcept C42219234 @default.
- W2164672022 hasConcept C534529494 @default.
- W2164672022 hasConcept C71924100 @default.
- W2164672022 hasConceptScore W2164672022C121332964 @default.
- W2164672022 hasConceptScore W2164672022C126322002 @default.
- W2164672022 hasConceptScore W2164672022C134306372 @default.
- W2164672022 hasConceptScore W2164672022C153294291 @default.
- W2164672022 hasConceptScore W2164672022C164705383 @default.
- W2164672022 hasConceptScore W2164672022C200457457 @default.
- W2164672022 hasConceptScore W2164672022C2776780178 @default.
- W2164672022 hasConceptScore W2164672022C2777080012 @default.
- W2164672022 hasConceptScore W2164672022C2777257755 @default.
- W2164672022 hasConceptScore W2164672022C2777311218 @default.
- W2164672022 hasConceptScore W2164672022C2777714996 @default.
- W2164672022 hasConceptScore W2164672022C2777944223 @default.
- W2164672022 hasConceptScore W2164672022C2778917391 @default.
- W2164672022 hasConceptScore W2164672022C2780030769 @default.
- W2164672022 hasConceptScore W2164672022C2989005 @default.
- W2164672022 hasConceptScore W2164672022C2992779976 @default.
- W2164672022 hasConceptScore W2164672022C33923547 @default.
- W2164672022 hasConceptScore W2164672022C42219234 @default.
- W2164672022 hasConceptScore W2164672022C534529494 @default.
- W2164672022 hasConceptScore W2164672022C71924100 @default.
- W2164672022 hasLocation W21646720221 @default.
- W2164672022 hasLocation W21646720222 @default.
- W2164672022 hasOpenAccess W2164672022 @default.
- W2164672022 hasPrimaryLocation W21646720221 @default.
- W2164672022 hasRelatedWork W2050792474 @default.
- W2164672022 hasRelatedWork W2055352203 @default.
- W2164672022 hasRelatedWork W2074720023 @default.
- W2164672022 hasRelatedWork W2089630903 @default.
- W2164672022 hasRelatedWork W2107845477 @default.
- W2164672022 hasRelatedWork W2164672022 @default.
- W2164672022 hasRelatedWork W2416686607 @default.
- W2164672022 hasRelatedWork W2606886472 @default.
- W2164672022 hasRelatedWork W2893359277 @default.
- W2164672022 hasRelatedWork W3030053427 @default.
- W2164672022 isParatext "false" @default.
- W2164672022 isRetracted "false" @default.
- W2164672022 magId "2164672022" @default.
- W2164672022 workType "article" @default.