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- W2164676915 abstract "This editorial refers to ‘Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting’[†][1], by C. Tamburino et al. , on page 1382 and ‘Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction’[‡][2], by O. Franzen et al. , on page 1373 The treatment of mitral valve regurgitation (MR) is an important clinical issue as MR represents >30% of native valve diseases.1 The results of surgery, in particular valve repair, are good, which sets a high standard for future innovative interventions.2 However, some observations suggest a potential for new interventions: (i) in current practice worldwide, surgery is denied to many patients with severe MR and symptoms;3 (ii) mitral valve repair is not always used or feasible;4 and (iii) surgical risks remain high in an important percentage of contemporary patients who are elderly with co-morbidities.Two main techniques have been introduced for percutaneous mitral valve repair: the edge to edge technique and the prosthetic ring annuloplasty.The edge to edge technique mimics the surgical procedure introduced by O. Alfieri, which creates a double mitral orifice by means of a few stitches securing the two leaflets together at their mid-part5 ( Figure 1 ). This technique has been performed percutaneously using a clip (E-valve MitraClip) made of a cobalt–chromium alloy and Dacron.6 Another design involved the use of one or two sutures deployed via a catheter-based device, but this has since been abandoned.7 The initial clinical experience with the edge to edge technique is mostly from the USA, including >500 patients; however, the reports in peer-reviewed journals are only based on the first 107 cases in the EVEREST registry.8,9 In addition, 279 patients are included in the EVEREST II … [1]: #fn-1 [2]: #fn-2" @default.
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- W2164676915 date "2010-04-11" @default.
- W2164676915 modified "2023-09-25" @default.
- W2164676915 title "'Edge to edge' percutaneous mitral valve repair in mitral regurgitation: it can be done but should it be done?" @default.
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- W2164676915 doi "https://doi.org/10.1093/eurheartj/ehq088" @default.
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