Matches in SemOpenAlex for { <https://semopenalex.org/work/W2164827258> ?p ?o ?g. }
- W2164827258 endingPage "77" @default.
- W2164827258 startingPage "65" @default.
- W2164827258 abstract "Information about histiocytic disease in cats is limited. The aim of this study was to document clinical findings and outcome in feline histiocytic disorders, and characterize the expression of PDGFRβ and KIT in order to identify potential treatment targets. Morphologically diagnosed feline histiocytic tumours were reviewed and characterized by immunohistochemistry (IHC). Five cases of feline progressive histiocytosis (FPH), eight histiocytic sarcomas (HS) and two haemophagocytic histiocytic sarcomas (HaeHS) were confirmed. PDGFRβ was variably positive in most histiocytic cases, while KIT was negative in all. Clinical presentation, treatment and outcome were also evaluated. Partial responses were recorded in measurable disease with tyrosine kinase inhibitors and lomustine, and radiotherapy achieved long-term control in some cases. Survival times were shortest in HaeHS and disseminated disease. PDGFRβ, but not KIT, may represent a therapeutic target in feline histiocytic disorders but more studies are needed to investigate other potential treatment targets." @default.
- W2164827258 created "2016-06-24" @default.
- W2164827258 creator A5024806593 @default.
- W2164827258 creator A5034852952 @default.
- W2164827258 creator A5044093712 @default.
- W2164827258 creator A5047147481 @default.
- W2164827258 creator A5073269661 @default.
- W2164827258 creator A5078706491 @default.
- W2164827258 date "2015-02-09" @default.
- W2164827258 modified "2023-10-03" @default.
- W2164827258 title "Clinical outcome, PDGFRβ and KIT expression in feline histiocytic disorders: a multicentre study" @default.
- W2164827258 cites W1517503932 @default.
- W2164827258 cites W1566005668 @default.
- W2164827258 cites W1963946178 @default.
- W2164827258 cites W1963975310 @default.
- W2164827258 cites W1967972996 @default.
- W2164827258 cites W1973950530 @default.
- W2164827258 cites W1974095449 @default.
- W2164827258 cites W1990160948 @default.
- W2164827258 cites W1995288911 @default.
- W2164827258 cites W1998446119 @default.
- W2164827258 cites W2009483016 @default.
- W2164827258 cites W2009619803 @default.
- W2164827258 cites W2019607817 @default.
- W2164827258 cites W2024173292 @default.
- W2164827258 cites W2028300826 @default.
- W2164827258 cites W2046338980 @default.
- W2164827258 cites W2048808545 @default.
- W2164827258 cites W2055522377 @default.
- W2164827258 cites W2056055966 @default.
- W2164827258 cites W2057215515 @default.
- W2164827258 cites W2063474895 @default.
- W2164827258 cites W2066898100 @default.
- W2164827258 cites W2075879542 @default.
- W2164827258 cites W2079734818 @default.
- W2164827258 cites W2091584836 @default.
- W2164827258 cites W2099782905 @default.
- W2164827258 cites W2104348422 @default.
- W2164827258 cites W2107665885 @default.
- W2164827258 cites W2110444317 @default.
- W2164827258 cites W2144690303 @default.
- W2164827258 cites W2168030213 @default.
- W2164827258 cites W2168526718 @default.
- W2164827258 cites W2314914316 @default.
- W2164827258 cites W4249255628 @default.
- W2164827258 doi "https://doi.org/10.1111/vco.12142" @default.
- W2164827258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25665137" @default.
- W2164827258 hasPublicationYear "2015" @default.
- W2164827258 type Work @default.
- W2164827258 sameAs 2164827258 @default.
- W2164827258 citedByCount "14" @default.
- W2164827258 countsByYear W21648272582017 @default.
- W2164827258 countsByYear W21648272582018 @default.
- W2164827258 countsByYear W21648272582019 @default.
- W2164827258 countsByYear W21648272582020 @default.
- W2164827258 countsByYear W21648272582021 @default.
- W2164827258 countsByYear W21648272582022 @default.
- W2164827258 countsByYear W21648272582023 @default.
- W2164827258 crossrefType "journal-article" @default.
- W2164827258 hasAuthorship W2164827258A5024806593 @default.
- W2164827258 hasAuthorship W2164827258A5034852952 @default.
- W2164827258 hasAuthorship W2164827258A5044093712 @default.
- W2164827258 hasAuthorship W2164827258A5047147481 @default.
- W2164827258 hasAuthorship W2164827258A5073269661 @default.
- W2164827258 hasAuthorship W2164827258A5078706491 @default.
- W2164827258 hasConcept C126322002 @default.
- W2164827258 hasConcept C142724271 @default.
- W2164827258 hasConcept C204232928 @default.
- W2164827258 hasConcept C2776310896 @default.
- W2164827258 hasConcept C2777578932 @default.
- W2164827258 hasConcept C2779134260 @default.
- W2164827258 hasConcept C2780174970 @default.
- W2164827258 hasConcept C43100952 @default.
- W2164827258 hasConcept C71924100 @default.
- W2164827258 hasConceptScore W2164827258C126322002 @default.
- W2164827258 hasConceptScore W2164827258C142724271 @default.
- W2164827258 hasConceptScore W2164827258C204232928 @default.
- W2164827258 hasConceptScore W2164827258C2776310896 @default.
- W2164827258 hasConceptScore W2164827258C2777578932 @default.
- W2164827258 hasConceptScore W2164827258C2779134260 @default.
- W2164827258 hasConceptScore W2164827258C2780174970 @default.
- W2164827258 hasConceptScore W2164827258C43100952 @default.
- W2164827258 hasConceptScore W2164827258C71924100 @default.
- W2164827258 hasFunder F4320320323 @default.
- W2164827258 hasIssue "1" @default.
- W2164827258 hasLocation W21648272581 @default.
- W2164827258 hasLocation W21648272582 @default.
- W2164827258 hasOpenAccess W2164827258 @default.
- W2164827258 hasPrimaryLocation W21648272581 @default.
- W2164827258 hasRelatedWork W1967164488 @default.
- W2164827258 hasRelatedWork W1974812484 @default.
- W2164827258 hasRelatedWork W2016647786 @default.
- W2164827258 hasRelatedWork W2104829374 @default.
- W2164827258 hasRelatedWork W2148576453 @default.
- W2164827258 hasRelatedWork W2315196178 @default.
- W2164827258 hasRelatedWork W2399393350 @default.
- W2164827258 hasRelatedWork W2468042209 @default.
- W2164827258 hasRelatedWork W3194971048 @default.