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- W2165002009 abstract "▴ Maruyama R, Sugio K, Yoshino I, et al . Hypermethylation of FHIT as a prognostic marker in non-small cell lung carcinoma. Cancer2004;100:1472–7. [OpenUrl][1][CrossRef][2][PubMed][3] DNA methylation of CpG sites in the promoter regions of tumour suppressor genes is a frequently acquired epigenetic event in the pathogenesis of many human cancers. The fragile histidine triad (FHIT) gene, located at chromosome 3p14.2, is a tumour suppressor gene. Methylation results in … [1]: {openurl}?query=rft.jtitle%253DCancer%26rft.stitle%253DCancer%26rft.aulast%253DMaruyama%26rft.auinit1%253DR.%26rft.volume%253D100%26rft.issue%253D7%26rft.spage%253D1472%26rft.epage%253D1477%26rft.atitle%253DHypermethylation%2Bof%2BFHIT%2Bas%2Ba%2Bprognostic%2Bmarker%2Bin%2Bnonsmall%2Bcell%2Blung%2Bcarcinoma.%26rft_id%253Dinfo%253Adoi%252F10.1002%252Fcncr.20144%26rft_id%253Dinfo%253Apmid%252F15042681%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1002/cncr.20144&link_type=DOI [3]: /lookup/external-ref?access_num=15042681&link_type=MED&atom=%2Fthoraxjnl%2F59%2F6%2F511.2.atom" @default.
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- W2165002009 date "2004-06-01" @default.
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- W2165002009 title "Hypermethylation of FHIT predicts poor prognosis in NSCLC" @default.
- W2165002009 doi "https://doi.org/10.1136/thx.2004.la0094" @default.
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