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• W2165034669 abstract "ABSTRACT The food-grade yeast Candida utilis has been engineered to confer a novel biosynthetic pathway for the production of carotenoids such as lycopene, β-carotene, and astaxanthin. The exogenous carotenoid biosynthesis genes were derived from the epiphytic bacterium Erwinia uredovora and the marine bacterium Agrobacterium aurantiacum . The carotenoid biosynthesis genes were individually modified based on the codon usage of the C. utilis glyceraldehyde 3-phosphate dehydrogenase gene and expressed in C. utilis under the control of the constitutive promoters and terminators derived from C. utilis . The resultant yeast strains accumulated lycopene, β-carotene, and astaxanthin in the cells at 1.1, 0.4, and 0.4 mg per g (dry weight) of cells, respectively. This was considered to be a result of the carbon flow into ergosterol biosynthesis being partially redirected to the nonendogenous pathway for carotenoid production." @default.
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• W2165034669 date "1998-04-01" @default.
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• W2165034669 title "Production of the Carotenoids Lycopene, β-Carotene, and Astaxanthin in the Food Yeast <i>Candida utilis</i>" @default.
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• W2165034669 doi "https://doi.org/10.1128/aem.64.4.1226-1229.1998" @default.
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