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- W2165146370 abstract "Homosexuality is a common occurrence in humans and other species, yet its genetic and evolutionary basis is poorly understood. Here, we formulate and study a series of simple mathematical models for the purpose of predicting empirical patterns that can be used to determine the form of selection that leads to polymorphism of genes influencing homosexuality. Specifically, we develop theory to make contrasting predictions about the genetic characteristics of genes influencing homosexuality including: (i) chromosomal location, (ii) dominance among segregating alleles and (iii) effect sizes that distinguish between the two major models for their polymorphism: the overdominance and sexual antagonism models. We conclude that the measurement of the genetic characteristics of quantitative trait loci (QTLs) found in genomic screens for genes influencing homosexuality can be highly informative in resolving the form of natural selection maintaining their polymorphism." @default.
- W2165146370 created "2016-06-24" @default.
- W2165146370 creator A5049094681 @default.
- W2165146370 creator A5086869086 @default.
- W2165146370 date "2006-09-26" @default.
- W2165146370 modified "2023-10-14" @default.
- W2165146370 title "Genetic models of homosexuality: generating testable predictions" @default.
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- W2165146370 doi "https://doi.org/10.1098/rspb.2006.3684" @default.
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