Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165284990> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2165284990 endingPage "29" @default.
- W2165284990 startingPage "23" @default.
- W2165284990 abstract "Hormone therapy (HT) is the most effective treatment at present available for climacteric symptoms. As harmful effects were highlighted in recent randomized clinical trials, the risk-benefit ratio does not favor the use of HT for prevention of cardiovascular diseases and bone fractures in postmenopausal women. Nevertheless, experimental and clinical trials suggest that adverse effects of HT basically depend on the estrogen and progestin formulation, dosage, route of administration, patient's age, associated diseases, and duration of treatment. All estrogen formulations and routes of administration have comparable beneficial effects on vasomotor and urogenital symptoms and on bone structure. But adverse effects may differ. Thus, cardiovascular and invasive breast cancer risks are higher with oral estrogen than with transdermal estradiol. However, transdermal estradiol is not free of inconveniences such as differences among individuals in absorption rates, loss of patches due to poor adhesion, and skin irritation. HT requires careful adjustment to each individual patient and continuous monitoring of clinical evolution. In the future, this adjustment and maybe the use of alternative routes such as intranasal could benefit from genetic screening to maximize in each individual the ratio between positive and adverse effects of HT." @default.
- W2165284990 created "2016-06-24" @default.
- W2165284990 creator A5046578855 @default.
- W2165284990 creator A5057850889 @default.
- W2165284990 date "2009-12-11" @default.
- W2165284990 modified "2023-09-25" @default.
- W2165284990 title "The role of intranasal estradiol spray in the management of moderate to severe vasomotor symptoms in menopausal women" @default.
- W2165284990 cites W1966638782 @default.
- W2165284990 cites W1976879422 @default.
- W2165284990 cites W1987997623 @default.
- W2165284990 cites W1998678464 @default.
- W2165284990 cites W2002770384 @default.
- W2165284990 cites W2034407896 @default.
- W2165284990 cites W2041476585 @default.
- W2165284990 cites W2050369644 @default.
- W2165284990 cites W2051790946 @default.
- W2165284990 cites W2054052966 @default.
- W2165284990 cites W2054850880 @default.
- W2165284990 cites W2073405962 @default.
- W2165284990 cites W2078747972 @default.
- W2165284990 cites W2087726976 @default.
- W2165284990 cites W2114607297 @default.
- W2165284990 cites W2134372734 @default.
- W2165284990 cites W2157863063 @default.
- W2165284990 cites W2170563960 @default.
- W2165284990 cites W4240296991 @default.
- W2165284990 doi "https://doi.org/10.3109/09513590903159698" @default.
- W2165284990 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19639494" @default.
- W2165284990 hasPublicationYear "2009" @default.
- W2165284990 type Work @default.
- W2165284990 sameAs 2165284990 @default.
- W2165284990 citedByCount "6" @default.
- W2165284990 countsByYear W21652849902014 @default.
- W2165284990 countsByYear W21652849902016 @default.
- W2165284990 countsByYear W21652849902020 @default.
- W2165284990 crossrefType "journal-article" @default.
- W2165284990 hasAuthorship W2165284990A5046578855 @default.
- W2165284990 hasAuthorship W2165284990A5057850889 @default.
- W2165284990 hasConcept C126322002 @default.
- W2165284990 hasConcept C168563851 @default.
- W2165284990 hasConcept C177713679 @default.
- W2165284990 hasConcept C197934379 @default.
- W2165284990 hasConcept C205679159 @default.
- W2165284990 hasConcept C2776093070 @default.
- W2165284990 hasConcept C2776214587 @default.
- W2165284990 hasConcept C2776607906 @default.
- W2165284990 hasConcept C2777164284 @default.
- W2165284990 hasConcept C2778562196 @default.
- W2165284990 hasConcept C2779279991 @default.
- W2165284990 hasConcept C2780159708 @default.
- W2165284990 hasConcept C29456083 @default.
- W2165284990 hasConcept C42407357 @default.
- W2165284990 hasConcept C535046627 @default.
- W2165284990 hasConcept C71924100 @default.
- W2165284990 hasConcept C98274493 @default.
- W2165284990 hasConceptScore W2165284990C126322002 @default.
- W2165284990 hasConceptScore W2165284990C168563851 @default.
- W2165284990 hasConceptScore W2165284990C177713679 @default.
- W2165284990 hasConceptScore W2165284990C197934379 @default.
- W2165284990 hasConceptScore W2165284990C205679159 @default.
- W2165284990 hasConceptScore W2165284990C2776093070 @default.
- W2165284990 hasConceptScore W2165284990C2776214587 @default.
- W2165284990 hasConceptScore W2165284990C2776607906 @default.
- W2165284990 hasConceptScore W2165284990C2777164284 @default.
- W2165284990 hasConceptScore W2165284990C2778562196 @default.
- W2165284990 hasConceptScore W2165284990C2779279991 @default.
- W2165284990 hasConceptScore W2165284990C2780159708 @default.
- W2165284990 hasConceptScore W2165284990C29456083 @default.
- W2165284990 hasConceptScore W2165284990C42407357 @default.
- W2165284990 hasConceptScore W2165284990C535046627 @default.
- W2165284990 hasConceptScore W2165284990C71924100 @default.
- W2165284990 hasConceptScore W2165284990C98274493 @default.
- W2165284990 hasIssue "1" @default.
- W2165284990 hasLocation W21652849901 @default.
- W2165284990 hasLocation W21652849902 @default.
- W2165284990 hasOpenAccess W2165284990 @default.
- W2165284990 hasPrimaryLocation W21652849901 @default.
- W2165284990 hasRelatedWork W1725742191 @default.
- W2165284990 hasRelatedWork W2016223312 @default.
- W2165284990 hasRelatedWork W2018360494 @default.
- W2165284990 hasRelatedWork W2094635093 @default.
- W2165284990 hasRelatedWork W2097715290 @default.
- W2165284990 hasRelatedWork W2105436464 @default.
- W2165284990 hasRelatedWork W2159229378 @default.
- W2165284990 hasRelatedWork W2318392287 @default.
- W2165284990 hasRelatedWork W4365443974 @default.
- W2165284990 hasRelatedWork W2182719101 @default.
- W2165284990 hasVolume "26" @default.
- W2165284990 isParatext "false" @default.
- W2165284990 isRetracted "false" @default.
- W2165284990 magId "2165284990" @default.
- W2165284990 workType "article" @default.