FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165301466> ?p ?o ?g. }

• W2165301466 endingPage "310" @default.
• W2165301466 startingPage "303" @default.
• W2165301466 abstract "Psoriasis affects 2‑4% of the population worldwide and its treatment is currently far from satisfactory. Calcipotriol and Portulaca oleracea have been reported to exhibit the capacity to inhibit inflammation in psoriatic patients and improve their clinical condition. However, the efficacy of a combination regimen of these two components remains unknown. The aim of the present study was to explore the therapeutic efficacy of P. oleracea extract combined with calcipotriol on plaque psoriasis and its potential mechanism. Eleven patients with plaque psoriasis were treated with humectant containing the active ingredients of P. oleracea extract, with or without 0.005% calcipotriol ointment in a right‑left bilateral lesion self‑control study. Differences were evaluated by investigation of the clinical efficacy, adverse effects, skin barrier function, histological structure, expression and proliferation of keratinocytes, differentiation markers (cytokeratin 10, filaggrin and loricrin), inflammatory factors [tumor necrosis factor (TNF)‑α and interleukin (IL)‑8], as well as the status of the nuclear factor κB (NF‑κB) pathway. The combination of P. oleracea and calcipotriol was revealed to decrease adverse effects, reduce transepidermal water loss, potently reverse keratinocyte differentiation dysfunction, and inhibit the expression of TNF‑α and IL‑8 and the phosphorylation of the NF‑κB inhibitor IκBα. This treatment is therefore anticipated to be suitable for use as a novel adjuvant therapy for psoriatic patients." @default.
• W2165301466 created "2016-06-24" @default.
• W2165301466 creator A5025563144 @default.
• W2165301466 creator A5032346670 @default.
• W2165301466 creator A5059301860 @default.
• W2165301466 creator A5061084605 @default.
• W2165301466 creator A5066650945 @default.
• W2165301466 creator A5069097747 @default.
• W2165301466 date "2014-12-08" @default.
• W2165301466 modified "2023-09-30" @default.
• W2165301466 title "Portulaca oleracea L. aids calcipotriol in reversing keratinocyte differentiation and skin barrier dysfunction in psoriasis through inhibition of the nuclear factor κB signaling pathway" @default.
• W2165301466 cites W1538005302 @default.
• W2165301466 cites W1909680668 @default.
• W2165301466 cites W1969658448 @default.
• W2165301466 cites W1976802252 @default.
• W2165301466 cites W1986301169 @default.
• W2165301466 cites W2000953362 @default.
• W2165301466 cites W2005779622 @default.
• W2165301466 cites W2005965928 @default.
• W2165301466 cites W2008276067 @default.
• W2165301466 cites W2008522868 @default.
• W2165301466 cites W2014532026 @default.
• W2165301466 cites W2029564208 @default.
• W2165301466 cites W2042855807 @default.
• W2165301466 cites W2043195650 @default.
• W2165301466 cites W2045065875 @default.
• W2165301466 cites W2047354818 @default.
• W2165301466 cites W2054712308 @default.
• W2165301466 cites W2057564399 @default.
• W2165301466 cites W2063106526 @default.
• W2165301466 cites W2068821867 @default.
• W2165301466 cites W2073046230 @default.
• W2165301466 cites W2074427640 @default.
• W2165301466 cites W2077826751 @default.
• W2165301466 cites W2088454193 @default.
• W2165301466 cites W2092824210 @default.
• W2165301466 cites W2094220422 @default.
• W2165301466 cites W2153702132 @default.
• W2165301466 cites W2157242677 @default.
• W2165301466 cites W2161441168 @default.
• W2165301466 cites W2168510531 @default.
• W2165301466 cites W2460529012 @default.
• W2165301466 cites W2743254891 @default.
• W2165301466 cites W4237921708 @default.
• W2165301466 cites W46637170 @default.
• W2165301466 cites W91224412 @default.
• W2165301466 doi "https://doi.org/10.3892/etm.2014.2116" @default.
• W2165301466 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4280941" @default.
• W2165301466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25574190" @default.
• W2165301466 hasPublicationYear "2014" @default.
• W2165301466 type Work @default.
• W2165301466 sameAs 2165301466 @default.
• W2165301466 citedByCount "8" @default.
• W2165301466 countsByYear W21653014662016 @default.
• W2165301466 countsByYear W21653014662018 @default.
• W2165301466 countsByYear W21653014662019 @default.
• W2165301466 countsByYear W21653014662020 @default.
• W2165301466 countsByYear W21653014662022 @default.
• W2165301466 countsByYear W21653014662023 @default.
• W2165301466 crossrefType "journal-article" @default.
• W2165301466 hasAuthorship W2165301466A5025563144 @default.
• W2165301466 hasAuthorship W2165301466A5032346670 @default.
• W2165301466 hasAuthorship W2165301466A5059301860 @default.
• W2165301466 hasAuthorship W2165301466A5061084605 @default.
• W2165301466 hasAuthorship W2165301466A5066650945 @default.
• W2165301466 hasAuthorship W2165301466A5069097747 @default.
• W2165301466 hasBestOaLocation W21653014661 @default.
• W2165301466 hasConcept C202751555 @default.
• W2165301466 hasConcept C203014093 @default.
• W2165301466 hasConcept C2776009542 @default.
• W2165301466 hasConcept C2777074287 @default.
• W2165301466 hasConcept C2780564577 @default.
• W2165301466 hasConcept C2908647359 @default.
• W2165301466 hasConcept C502942594 @default.
• W2165301466 hasConcept C55493867 @default.
• W2165301466 hasConcept C71924100 @default.
• W2165301466 hasConcept C86803240 @default.
• W2165301466 hasConcept C98274493 @default.
• W2165301466 hasConcept C99454951 @default.
• W2165301466 hasConceptScore W2165301466C202751555 @default.
• W2165301466 hasConceptScore W2165301466C203014093 @default.
• W2165301466 hasConceptScore W2165301466C2776009542 @default.
• W2165301466 hasConceptScore W2165301466C2777074287 @default.
• W2165301466 hasConceptScore W2165301466C2780564577 @default.
• W2165301466 hasConceptScore W2165301466C2908647359 @default.
• W2165301466 hasConceptScore W2165301466C502942594 @default.
• W2165301466 hasConceptScore W2165301466C55493867 @default.
• W2165301466 hasConceptScore W2165301466C71924100 @default.
• W2165301466 hasConceptScore W2165301466C86803240 @default.
• W2165301466 hasConceptScore W2165301466C98274493 @default.
• W2165301466 hasConceptScore W2165301466C99454951 @default.
• W2165301466 hasIssue "2" @default.
• W2165301466 hasLocation W21653014661 @default.
• W2165301466 hasLocation W21653014662 @default.
• W2165301466 hasLocation W21653014663 @default.
• W2165301466 hasLocation W21653014664 @default.
• W2165301466 hasOpenAccess W2165301466 @default.
• W2165301466 hasPrimaryLocation W21653014661 @default.

• next