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- W2165364489 abstract "Thymuses of mice of the C57B1/6 and AKR strains from ten-day-old embryos through one day after birth were studied histologically and histochemically. New evidence is presented of the penetration of the endodermal epithelium of the third pharyngeal pouch of ten-day-old embryos by basophilic lymphoblasts. Both alkaline and acid phosphatases showed different distributions in the thymuses of the two strains at 12 and 13 days. By 15 and 16 days, alkaline phosphatase activity in thymuses of the C57B1/6 strain was peripheral; in thymuses of AKR mice, it was present throughout the lobes. In the C57B1/6 lobes, little acid phosphatase activity was observed; however, in the AKR thymuses, activity was strong and was located especially in the cortex. The characteristic patterns of enzymatic activities of the postnatal thymuses were well established at 17–18 days. Prenatally the medullae of the thymuses of both strains contained esterase-rich inclusion cells and epithelial reticular cells which occurred singly or as nests of cells. The inclusion cells also possessed alkaline phosphatase activity. It is suggested that these cells may contain the precursors of the humoral factor(s) of the thymus. The thymuses were also studied after treatment with the periodic acid-Schiff technique for glycogen and the procedure for showing sites of adenosine triphosphatase activity." @default.
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- W2165364489 date "1965-05-01" @default.
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- W2165364489 title "Studies on the thymus of the mammal. XIV. Histology and histochemistry of embryonic and early postnatal thymuses of C57Bl/6 and AKR strain mice" @default.
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- W2165364489 doi "https://doi.org/10.1002/aja.1001160307" @default.
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