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- W2165469062 abstract "<i>Background/Aims:</i> To evaluate the long-term outcome of surgical and non-surgical local treatments of patients with hepatocellular carcinoma (HCC). <i>Methods:</i> We stratified a cohort of 278 HCC patients using six independent predictors of survival according to the Vienna survival model for HCC (VISUM-HCC). <i>Results:</i> Prior to therapy, 224 HCC patients presented with VISUM stage 1 (median survival 18 months) while 29 patients were classified as VISUM stage 2 (median survival 4 months) and 25 patients as VISUM stage 3 (median survival 3 months). A highly significant (p < 0.001) improved survival time was observed in VISUM stage 1 patients treated with liver resection (n = 52; median survival 37 months) or chemoembolization (TACE) and subsequent radiofrequency ablation (RFA) (n = 44; median survival 45 months) as compared to patients receiving chemoembolization alone (n = 107; median survival 13 months) or patients treated by tamoxifen only (n = 21; median survival 6 months). Chemoembolization alone significantly (p ≤ 0.004) improved survival time in VISUM stage 1–2 patients but not (p = 0.341) in VISUM stage 3 patients in comparison to those treated by tamoxifen. <i>Conclusion:</i> Both liver resection or combined chemoembolization and RFA improve markedly the survival of patients with HCC." @default.
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- W2165469062 date "2007-01-01" @default.
- W2165469062 modified "2023-10-18" @default.
- W2165469062 title "Liver Resection or Combined Chemoembolization and Radiofrequency Ablation Improve Survival in Patients with Hepatocellular Carcinoma" @default.
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- W2165469062 doi "https://doi.org/10.1159/000104730" @default.
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