FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165475498> ?p ?o ?g. }

• W2165475498 abstract "Extensive studies of BRCA1- and BRCA2-associated breast tumours have been carried out in the few years since the identification of these familial breast cancer predisposing genes. The morphological studies suggest that BRCA1 tumours differ from BRCA2 tumours and from sporadic breast cancers. Recent progress in immunohistochemistry and molecular biology techniques has enabled in-depth investigation of molecular pathology of these tumours. Studies to date have investigated issues such as steroid hormone receptor expression, mutation status of tumour suppressor genes TP53 and c-erbB2, and expression profiles of cell cycle proteins p21, p27 and cyclin D1. Despite relative paucity of data, strong evidence of unique biological characteristics of BRCA1-associated breast cancer is accumulating. BRCA1-associated tumours appear to show an increased frequency of TP53 mutations, frequent p53 protein stabilization and absence of imunoreactivity for steroid hormone receptors. Further studies of larger number of samples of both BRCA1- and BRCA2-associated tumours are necessary to clarify and confirm these observations." @default.
• W2165475498 created "2016-06-24" @default.
• W2165475498 creator A5047329745 @default.
• W2165475498 creator A5059866043 @default.
• W2165475498 date "1999-12-01" @default.
• W2165475498 modified "2023-10-13" @default.
• W2165475498 title "The pathology of familial breast cancer: Immunohistochemistry and molecular analysis" @default.
• W2165475498 cites W112854329 @default.
• W2165475498 cites W1531559622 @default.
• W2165475498 cites W1650185154 @default.
• W2165475498 cites W1651458958 @default.
• W2165475498 cites W1881645183 @default.
• W2165475498 cites W1964618450 @default.
• W2165475498 cites W1967080458 @default.
• W2165475498 cites W1975384399 @default.
• W2165475498 cites W1997201436 @default.
• W2165475498 cites W2013309931 @default.
• W2165475498 cites W2017420193 @default.
• W2165475498 cites W2024226643 @default.
• W2165475498 cites W2027304309 @default.
• W2165475498 cites W2037327253 @default.
• W2165475498 cites W2039137615 @default.
• W2165475498 cites W2054139127 @default.
• W2165475498 cites W2062329553 @default.
• W2165475498 cites W2063335267 @default.
• W2165475498 cites W2078783773 @default.
• W2165475498 cites W2089454614 @default.
• W2165475498 cites W2095632857 @default.
• W2165475498 cites W2097384171 @default.
• W2165475498 cites W2112187879 @default.
• W2165475498 cites W2123933505 @default.
• W2165475498 cites W2135188842 @default.
• W2165475498 cites W2135535670 @default.
• W2165475498 cites W2138798180 @default.
• W2165475498 cites W2142874345 @default.
• W2165475498 cites W2160459637 @default.
• W2165475498 cites W2318491945 @default.
• W2165475498 cites W2332724067 @default.
• W2165475498 cites W4302510291 @default.
• W2165475498 cites W58216398 @default.
• W2165475498 doi "https://doi.org/10.1186/bcr11" @default.
• W2165475498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/138499" @default.
• W2165475498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11250681" @default.
• W2165475498 hasPublicationYear "1999" @default.
• W2165475498 type Work @default.
• W2165475498 sameAs 2165475498 @default.
• W2165475498 citedByCount "64" @default.
• W2165475498 countsByYear W21654754982012 @default.
• W2165475498 countsByYear W21654754982013 @default.
• W2165475498 countsByYear W21654754982014 @default.
• W2165475498 countsByYear W21654754982015 @default.
• W2165475498 countsByYear W21654754982016 @default.
• W2165475498 countsByYear W21654754982017 @default.
• W2165475498 countsByYear W21654754982018 @default.
• W2165475498 countsByYear W21654754982019 @default.
• W2165475498 countsByYear W21654754982020 @default.
• W2165475498 crossrefType "journal-article" @default.
• W2165475498 hasAuthorship W2165475498A5047329745 @default.
• W2165475498 hasAuthorship W2165475498A5059866043 @default.
• W2165475498 hasBestOaLocation W21654754981 @default.
• W2165475498 hasConcept C104317684 @default.
• W2165475498 hasConcept C121608353 @default.
• W2165475498 hasConcept C126322002 @default.
• W2165475498 hasConcept C142724271 @default.
• W2165475498 hasConcept C143998085 @default.
• W2165475498 hasConcept C199835354 @default.
• W2165475498 hasConcept C204232928 @default.
• W2165475498 hasConcept C23589133 @default.
• W2165475498 hasConcept C2779544216 @default.
• W2165475498 hasConcept C2780140570 @default.
• W2165475498 hasConcept C29537977 @default.
• W2165475498 hasConcept C502942594 @default.
• W2165475498 hasConcept C530470458 @default.
• W2165475498 hasConcept C54355233 @default.
• W2165475498 hasConcept C71924100 @default.
• W2165475498 hasConcept C74092355 @default.
• W2165475498 hasConcept C84606932 @default.
• W2165475498 hasConcept C86803240 @default.
• W2165475498 hasConceptScore W2165475498C104317684 @default.
• W2165475498 hasConceptScore W2165475498C121608353 @default.
• W2165475498 hasConceptScore W2165475498C126322002 @default.
• W2165475498 hasConceptScore W2165475498C142724271 @default.
• W2165475498 hasConceptScore W2165475498C143998085 @default.
• W2165475498 hasConceptScore W2165475498C199835354 @default.
• W2165475498 hasConceptScore W2165475498C204232928 @default.
• W2165475498 hasConceptScore W2165475498C23589133 @default.
• W2165475498 hasConceptScore W2165475498C2779544216 @default.
• W2165475498 hasConceptScore W2165475498C2780140570 @default.
• W2165475498 hasConceptScore W2165475498C29537977 @default.
• W2165475498 hasConceptScore W2165475498C502942594 @default.
• W2165475498 hasConceptScore W2165475498C530470458 @default.
• W2165475498 hasConceptScore W2165475498C54355233 @default.
• W2165475498 hasConceptScore W2165475498C71924100 @default.
• W2165475498 hasConceptScore W2165475498C74092355 @default.
• W2165475498 hasConceptScore W2165475498C84606932 @default.
• W2165475498 hasConceptScore W2165475498C86803240 @default.
• W2165475498 hasIssue "1" @default.
• W2165475498 hasLocation W21654754981 @default.
• W2165475498 hasLocation W21654754982 @default.
• W2165475498 hasLocation W21654754983 @default.

• next