Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165510902> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2165510902 endingPage "363" @default.
- W2165510902 startingPage "363" @default.
- W2165510902 abstract "Volatile anesthetics have been shown to decrease baroreflex. In humans, cardiovagal baroreflex curve is best described to be sigmoidal and analysis of sigmoid model can provide more information, such as threshold (THR), saturation (SAT), maximal gain (Gmax), operating range (OR, difference between THR and SAT), operational point (OP, relative position of resting set point within the OR) in addition to the linear gain. We compared the changes in the sigmoid model of the systolic blood pressure (SBP)-RR interval relation between awake state and general anesthesia.Sigmoid curve was obtained using the 'modified Oxford technique' (bolus sodium nitroprusside followed by bolus phenylephrine) to perturb SBP in awake group and 2 vol% sevoflurane anesthesia group. Radial arterial beat-by-beat SBP and raw RR interval data points were plotted and then binned in 2 mmHg SBP increments. Curve fittings were performed using symmetric four-parameter sigmoid model and asymmetric five-parameter sigmoid model. Gmax was calculated from the first derivative of the logistic function.Compared with awake control, general anesthesia caused decreases of linear gain, Gmax and OR. RR interval THR and SBP THR were unaffected, whereas SBP SAT increased and RR interval SAT decreased, resulting from reduced linear gain and curvature parameter. Resting set point fell and OP shifted significantly to THR region.Sigmoidal baroreflex curve revealed diminished gains, OR and OP during general anesthesia. Moreover, our results demonstrate that the analysis of sigmoid baroreflex arc across the entire baroreflex range provide more unique information beyond that of linear gain." @default.
- W2165510902 created "2016-06-24" @default.
- W2165510902 creator A5005135577 @default.
- W2165510902 creator A5090099540 @default.
- W2165510902 date "2009-01-01" @default.
- W2165510902 modified "2023-10-16" @default.
- W2165510902 title "Change in characteristics of human vagal sigmoidal baroreflex curve during conscious state and general anesthesia" @default.
- W2165510902 cites W1934601864 @default.
- W2165510902 cites W2011015110 @default.
- W2165510902 cites W2051008511 @default.
- W2165510902 cites W2069040953 @default.
- W2165510902 cites W2079286733 @default.
- W2165510902 cites W2092991372 @default.
- W2165510902 cites W2101831203 @default.
- W2165510902 cites W2112458144 @default.
- W2165510902 cites W2114551957 @default.
- W2165510902 cites W2119869975 @default.
- W2165510902 cites W2122393533 @default.
- W2165510902 cites W2123593024 @default.
- W2165510902 cites W2135748953 @default.
- W2165510902 cites W2138851126 @default.
- W2165510902 cites W2404865916 @default.
- W2165510902 cites W2423942202 @default.
- W2165510902 cites W2328049473 @default.
- W2165510902 doi "https://doi.org/10.4097/kjae.2009.56.4.363" @default.
- W2165510902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30625754" @default.
- W2165510902 hasPublicationYear "2009" @default.
- W2165510902 type Work @default.
- W2165510902 sameAs 2165510902 @default.
- W2165510902 citedByCount "0" @default.
- W2165510902 crossrefType "journal-article" @default.
- W2165510902 hasAuthorship W2165510902A5005135577 @default.
- W2165510902 hasAuthorship W2165510902A5090099540 @default.
- W2165510902 hasBestOaLocation W21655109021 @default.
- W2165510902 hasConcept C119857082 @default.
- W2165510902 hasConcept C126322002 @default.
- W2165510902 hasConcept C191237925 @default.
- W2165510902 hasConcept C2777952589 @default.
- W2165510902 hasConcept C2777953023 @default.
- W2165510902 hasConcept C41008148 @default.
- W2165510902 hasConcept C42219234 @default.
- W2165510902 hasConcept C43376680 @default.
- W2165510902 hasConcept C50644808 @default.
- W2165510902 hasConcept C71924100 @default.
- W2165510902 hasConcept C81388566 @default.
- W2165510902 hasConcept C84393581 @default.
- W2165510902 hasConceptScore W2165510902C119857082 @default.
- W2165510902 hasConceptScore W2165510902C126322002 @default.
- W2165510902 hasConceptScore W2165510902C191237925 @default.
- W2165510902 hasConceptScore W2165510902C2777952589 @default.
- W2165510902 hasConceptScore W2165510902C2777953023 @default.
- W2165510902 hasConceptScore W2165510902C41008148 @default.
- W2165510902 hasConceptScore W2165510902C42219234 @default.
- W2165510902 hasConceptScore W2165510902C43376680 @default.
- W2165510902 hasConceptScore W2165510902C50644808 @default.
- W2165510902 hasConceptScore W2165510902C71924100 @default.
- W2165510902 hasConceptScore W2165510902C81388566 @default.
- W2165510902 hasConceptScore W2165510902C84393581 @default.
- W2165510902 hasIssue "4" @default.
- W2165510902 hasLocation W21655109021 @default.
- W2165510902 hasLocation W21655109022 @default.
- W2165510902 hasOpenAccess W2165510902 @default.
- W2165510902 hasPrimaryLocation W21655109021 @default.
- W2165510902 hasRelatedWork W1680012226 @default.
- W2165510902 hasRelatedWork W2023610543 @default.
- W2165510902 hasRelatedWork W2049957143 @default.
- W2165510902 hasRelatedWork W2055757354 @default.
- W2165510902 hasRelatedWork W2085194324 @default.
- W2165510902 hasRelatedWork W2108711978 @default.
- W2165510902 hasRelatedWork W2129609331 @default.
- W2165510902 hasRelatedWork W2413723564 @default.
- W2165510902 hasRelatedWork W2494319584 @default.
- W2165510902 hasRelatedWork W68097435 @default.
- W2165510902 hasVolume "56" @default.
- W2165510902 isParatext "false" @default.
- W2165510902 isRetracted "false" @default.
- W2165510902 magId "2165510902" @default.
- W2165510902 workType "article" @default.