Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165563873> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2165563873 abstract "Guppies pretreated with 1.1 μmol/L diazinon (0.5 times the LC50 with the guppy) for 7 d were less susceptible to the toxicity of the compound. The LC50 in these fish was about five times higher than that in nonpretreated animals. The lethal body burden and the slope of the concentration-response curve of diazinon in pretreated guppies were similar to those in zebra fish. The 7-d pretreatment of zebra fish with 12 μmol/L diazinon (0.5 times the LC50 with the zebra fish) did not affect the susceptibility of this species to diazinon. The pretreatment of guppies resulted in a strong inhibition of the formation of diazoxon and pyrimidinol during incubations of diazinon with the hepatic postmitochondrial supernatant. During exposure of guppies and zebra fish to diazinon, the tissue concentration of the metabolite, pyrimidinol, initially increased and then declined to very low levels. In the guppy, concurrently with the decrease of the metabolite concentration, the parent compound began accumulating again after a temporary steady state. The hypotheses of this paper are that the toxicity of diazinon in the guppy is due to its metabolism to a highly toxic metabolite, likely diazoxon; and in zebra fish or pretreated guppies having low rates of diazinon metabolism toxicity is due to the accumulation of the parent compound." @default.
- W2165563873 created "2016-06-24" @default.
- W2165563873 creator A5020213297 @default.
- W2165563873 creator A5020948443 @default.
- W2165563873 creator A5028362037 @default.
- W2165563873 creator A5088259377 @default.
- W2165563873 creator A5090781057 @default.
- W2165563873 date "1993-07-01" @default.
- W2165563873 modified "2023-10-04" @default.
- W2165563873 title "Comparative diazinon toxicity in guppy and zebra fish: Different role of oxidative metabolism" @default.
- W2165563873 cites W1968134217 @default.
- W2165563873 cites W1969263844 @default.
- W2165563873 cites W1971832407 @default.
- W2165563873 cites W1975168714 @default.
- W2165563873 cites W1998194919 @default.
- W2165563873 cites W2010434464 @default.
- W2165563873 cites W2012453440 @default.
- W2165563873 cites W2017094110 @default.
- W2165563873 cites W2024339512 @default.
- W2165563873 cites W2040851924 @default.
- W2165563873 cites W2044366000 @default.
- W2165563873 cites W2051883830 @default.
- W2165563873 cites W2057355570 @default.
- W2165563873 cites W2058160747 @default.
- W2165563873 cites W2060485402 @default.
- W2165563873 cites W2064281959 @default.
- W2165563873 cites W2089305527 @default.
- W2165563873 cites W2094433444 @default.
- W2165563873 cites W2161393112 @default.
- W2165563873 cites W2172064893 @default.
- W2165563873 cites W83672363 @default.
- W2165563873 doi "https://doi.org/10.1002/etc.5620120713" @default.
- W2165563873 hasPublicationYear "1993" @default.
- W2165563873 type Work @default.
- W2165563873 sameAs 2165563873 @default.
- W2165563873 citedByCount "30" @default.
- W2165563873 countsByYear W21655638732012 @default.
- W2165563873 countsByYear W21655638732013 @default.
- W2165563873 countsByYear W21655638732019 @default.
- W2165563873 crossrefType "journal-article" @default.
- W2165563873 hasAuthorship W2165563873A5020213297 @default.
- W2165563873 hasAuthorship W2165563873A5020948443 @default.
- W2165563873 hasAuthorship W2165563873A5028362037 @default.
- W2165563873 hasAuthorship W2165563873A5088259377 @default.
- W2165563873 hasAuthorship W2165563873A5090781057 @default.
- W2165563873 hasConcept C161176658 @default.
- W2165563873 hasConcept C178790620 @default.
- W2165563873 hasConcept C185592680 @default.
- W2165563873 hasConcept C18903297 @default.
- W2165563873 hasConcept C2777477808 @default.
- W2165563873 hasConcept C2779762703 @default.
- W2165563873 hasConcept C2779842916 @default.
- W2165563873 hasConcept C2909208804 @default.
- W2165563873 hasConcept C29730261 @default.
- W2165563873 hasConcept C33070731 @default.
- W2165563873 hasConcept C505870484 @default.
- W2165563873 hasConcept C55493867 @default.
- W2165563873 hasConcept C86803240 @default.
- W2165563873 hasConceptScore W2165563873C161176658 @default.
- W2165563873 hasConceptScore W2165563873C178790620 @default.
- W2165563873 hasConceptScore W2165563873C185592680 @default.
- W2165563873 hasConceptScore W2165563873C18903297 @default.
- W2165563873 hasConceptScore W2165563873C2777477808 @default.
- W2165563873 hasConceptScore W2165563873C2779762703 @default.
- W2165563873 hasConceptScore W2165563873C2779842916 @default.
- W2165563873 hasConceptScore W2165563873C2909208804 @default.
- W2165563873 hasConceptScore W2165563873C29730261 @default.
- W2165563873 hasConceptScore W2165563873C33070731 @default.
- W2165563873 hasConceptScore W2165563873C505870484 @default.
- W2165563873 hasConceptScore W2165563873C55493867 @default.
- W2165563873 hasConceptScore W2165563873C86803240 @default.
- W2165563873 hasLocation W21655638731 @default.
- W2165563873 hasOpenAccess W2165563873 @default.
- W2165563873 hasPrimaryLocation W21655638731 @default.
- W2165563873 hasRelatedWork W1133211749 @default.
- W2165563873 hasRelatedWork W1971832407 @default.
- W2165563873 hasRelatedWork W1982532750 @default.
- W2165563873 hasRelatedWork W1991001716 @default.
- W2165563873 hasRelatedWork W1992481889 @default.
- W2165563873 hasRelatedWork W2038241119 @default.
- W2165563873 hasRelatedWork W2073153941 @default.
- W2165563873 hasRelatedWork W2089305527 @default.
- W2165563873 hasRelatedWork W2094022965 @default.
- W2165563873 hasRelatedWork W2094433444 @default.
- W2165563873 hasRelatedWork W2107780630 @default.
- W2165563873 hasRelatedWork W2115300036 @default.
- W2165563873 hasRelatedWork W2119058076 @default.
- W2165563873 hasRelatedWork W2150421202 @default.
- W2165563873 hasRelatedWork W2265328128 @default.
- W2165563873 hasRelatedWork W2610111452 @default.
- W2165563873 hasRelatedWork W2766960049 @default.
- W2165563873 hasRelatedWork W2936178024 @default.
- W2165563873 hasRelatedWork W2313411183 @default.
- W2165563873 hasRelatedWork W3120228954 @default.
- W2165563873 isParatext "false" @default.
- W2165563873 isRetracted "false" @default.
- W2165563873 magId "2165563873" @default.
- W2165563873 workType "article" @default.