FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165607262> ?p ?o ?g. }

• W2165607262 endingPage "1198" @default.
• W2165607262 startingPage "1191" @default.
• W2165607262 abstract "Abstract Rationale: The growing recognition of the importance of splicing, together with rapidly accumulating RNA-sequencing data, demand robust high-throughput approaches, which efficiently analyze experimentally derived whole-transcriptome splice profiles. Results: We have developed a computational approach, called SNPlice, for identifying cis-acting, splice-modulating variants from RNA-seq datasets. SNPlice mines RNA-seq datasets to find reads that span single-nucleotide variant (SNV) loci and nearby splice junctions, assessing the co-occurrence of variants and molecules that remain unspliced at nearby exon–intron boundaries. Hence, SNPlice highlights variants preferentially occurring on intron-containing molecules, possibly resulting from altered splicing. To illustrate co-occurrence of variant nucleotide and exon–intron boundary, allele-specific sequencing was used. SNPlice results are generally consistent with splice-prediction tools, but also indicate splice-modulating elements missed by other algorithms. SNPlice can be applied to identify variants that correlate with unexpected splicing events, and to measure the splice-modulating potential of canonical splice-site SNVs. Availability and implementation: SNPlice is freely available for download from https://code.google.com/p/snplice/ as a self-contained binary package for 64-bit Linux computers and as python source-code. Contact: pmudvari@gwu.edu or horvatha@gwu.edu Supplementary information: Supplementary data are available at Bioinformatics online." @default.
• W2165607262 created "2016-06-24" @default.
• W2165607262 creator A5001354047 @default.
• W2165607262 creator A5009587295 @default.
• W2165607262 creator A5030754052 @default.
• W2165607262 creator A5037409857 @default.
• W2165607262 creator A5047818946 @default.
• W2165607262 creator A5058471533 @default.
• W2165607262 creator A5072196170 @default.
• W2165607262 creator A5073568865 @default.
• W2165607262 date "2014-12-06" @default.
• W2165607262 modified "2023-10-14" @default.
• W2165607262 title "SNPlice: variants that modulate Intron retention from RNA-sequencing data" @default.
• W2165607262 cites W1968569455 @default.
• W2165607262 cites W1973002047 @default.
• W2165607262 cites W1973207504 @default.
• W2165607262 cites W1977019675 @default.
• W2165607262 cites W1978883675 @default.
• W2165607262 cites W1987374058 @default.
• W2165607262 cites W1988201451 @default.
• W2165607262 cites W1998122962 @default.
• W2165607262 cites W2007872099 @default.
• W2165607262 cites W2011920499 @default.
• W2165607262 cites W2014181394 @default.
• W2165607262 cites W2016699802 @default.
• W2165607262 cites W2024122679 @default.
• W2165607262 cites W2034691490 @default.
• W2165607262 cites W2042877132 @default.
• W2165607262 cites W2051604556 @default.
• W2165607262 cites W2052952075 @default.
• W2165607262 cites W2058737848 @default.
• W2165607262 cites W2060181803 @default.
• W2165607262 cites W2060745559 @default.
• W2165607262 cites W2061657172 @default.
• W2165607262 cites W2073954801 @default.
• W2165607262 cites W2092756750 @default.
• W2165607262 cites W2095998476 @default.
• W2165607262 cites W2097617881 @default.
• W2165607262 cites W2106685977 @default.
• W2165607262 cites W2108234281 @default.
• W2165607262 cites W2110400205 @default.
• W2165607262 cites W2116220051 @default.
• W2165607262 cites W2117131162 @default.
• W2165607262 cites W2118994793 @default.
• W2165607262 cites W2135577623 @default.
• W2165607262 cites W2136549268 @default.
• W2165607262 cites W2140729960 @default.
• W2165607262 cites W2141458291 @default.
• W2165607262 cites W2141602707 @default.
• W2165607262 cites W2144655298 @default.
• W2165607262 cites W2147491566 @default.
• W2165607262 cites W2151462466 @default.
• W2165607262 cites W2156410844 @default.
• W2165607262 cites W2161839829 @default.
• W2165607262 cites W2162338462 @default.
• W2165607262 cites W2166960413 @default.
• W2165607262 cites W2259938310 @default.
• W2165607262 cites W4238325202 @default.
• W2165607262 doi "https://doi.org/10.1093/bioinformatics/btu804" @default.
• W2165607262 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4393518" @default.
• W2165607262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25481010" @default.
• W2165607262 hasPublicationYear "2014" @default.
• W2165607262 type Work @default.
• W2165607262 sameAs 2165607262 @default.
• W2165607262 citedByCount "17" @default.
• W2165607262 countsByYear W21656072622015 @default.
• W2165607262 countsByYear W21656072622016 @default.
• W2165607262 countsByYear W21656072622017 @default.
• W2165607262 countsByYear W21656072622018 @default.
• W2165607262 countsByYear W21656072622019 @default.
• W2165607262 countsByYear W21656072622020 @default.
• W2165607262 countsByYear W21656072622022 @default.
• W2165607262 countsByYear W21656072622023 @default.
• W2165607262 crossrefType "journal-article" @default.
• W2165607262 hasAuthorship W2165607262A5001354047 @default.
• W2165607262 hasAuthorship W2165607262A5009587295 @default.
• W2165607262 hasAuthorship W2165607262A5030754052 @default.
• W2165607262 hasAuthorship W2165607262A5037409857 @default.
• W2165607262 hasAuthorship W2165607262A5047818946 @default.
• W2165607262 hasAuthorship W2165607262A5058471533 @default.
• W2165607262 hasAuthorship W2165607262A5072196170 @default.
• W2165607262 hasAuthorship W2165607262A5073568865 @default.
• W2165607262 hasBestOaLocation W21656072621 @default.
• W2165607262 hasConcept C104317684 @default.
• W2165607262 hasConcept C107397762 @default.
• W2165607262 hasConcept C150194340 @default.
• W2165607262 hasConcept C162317418 @default.
• W2165607262 hasConcept C2780989783 @default.
• W2165607262 hasConcept C36823959 @default.
• W2165607262 hasConcept C54355233 @default.
• W2165607262 hasConcept C54458228 @default.
• W2165607262 hasConcept C67705224 @default.
• W2165607262 hasConcept C70721500 @default.
• W2165607262 hasConcept C86803240 @default.
• W2165607262 hasConcept C94671646 @default.
• W2165607262 hasConceptScore W2165607262C104317684 @default.
• W2165607262 hasConceptScore W2165607262C107397762 @default.
• W2165607262 hasConceptScore W2165607262C150194340 @default.

• next