Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165624684> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2165624684 abstract "To describe the beneficial effects of estradiol in a severely asthmatic woman with premenstrual worsening of asthma.A 50-year-old white woman, with a 14-year history of severe steroid-dependent asthma and monthly premenstrual worsening of asthma, was randomized to receive estradiol 2 mg or placebo for 6 days during the late luteal phase (days 23-28) of 2 successive menstrual cycles. Despite greater prednisone and inhaled beta-agonist use during the late luteal phase of the placebo cycle, the patient exhibited improved asthma symptoms, pulmonary function, and peak expiratory flows, as well as lower values for biomarkers of airway inflammation during the same time period of the estradiol cycle.This subject's response to estradiol was in contrast to results of a randomized, controlled trial involving patients with predominantly mild asthma under excellent control. The discrepant observations for this case versus the majority of subjects in the randomized, controlled study suggest that premenstrual asthma (PMA) and a beneficial response to estradiol may be more likely in women with severe asthma.The administration of estradiol during the late luteal phase of the menstrual cycle to a woman with severe asthma with PMA was associated with improved asthma symptoms, pulmonary function, and peak expiratory flows, and lower serum eosinophil protein X and urinary leukotriene E(4) biomarker concentrations. Thus, estradiol's potential role in women with severe asthma and PMA may warrant further exploration in this subgroup." @default.
- W2165624684 created "2016-06-24" @default.
- W2165624684 creator A5021326910 @default.
- W2165624684 creator A5028315546 @default.
- W2165624684 creator A5073337287 @default.
- W2165624684 creator A5089807785 @default.
- W2165624684 date "2003-11-01" @default.
- W2165624684 modified "2023-09-27" @default.
- W2165624684 title "Estradiol in Severe Asthma with Premenstrual Worsening" @default.
- W2165624684 cites W1994994247 @default.
- W2165624684 cites W1996605427 @default.
- W2165624684 cites W2003292549 @default.
- W2165624684 cites W2011488948 @default.
- W2165624684 cites W2014539589 @default.
- W2165624684 cites W2015268712 @default.
- W2165624684 cites W2017805361 @default.
- W2165624684 cites W2028200436 @default.
- W2165624684 cites W2040390119 @default.
- W2165624684 cites W2044171379 @default.
- W2165624684 cites W2058715299 @default.
- W2165624684 cites W2065174142 @default.
- W2165624684 cites W2071410984 @default.
- W2165624684 cites W2077283768 @default.
- W2165624684 cites W2079075121 @default.
- W2165624684 cites W2090786287 @default.
- W2165624684 cites W2108298768 @default.
- W2165624684 cites W2111609315 @default.
- W2165624684 cites W2115209627 @default.
- W2165624684 cites W2159926856 @default.
- W2165624684 cites W4242530507 @default.
- W2165624684 doi "https://doi.org/10.1345/aph.1d090" @default.
- W2165624684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14565797" @default.
- W2165624684 hasPublicationYear "2003" @default.
- W2165624684 type Work @default.
- W2165624684 sameAs 2165624684 @default.
- W2165624684 citedByCount "24" @default.
- W2165624684 countsByYear W21656246842012 @default.
- W2165624684 countsByYear W21656246842013 @default.
- W2165624684 countsByYear W21656246842015 @default.
- W2165624684 countsByYear W21656246842017 @default.
- W2165624684 countsByYear W21656246842022 @default.
- W2165624684 crossrefType "journal-article" @default.
- W2165624684 hasAuthorship W2165624684A5021326910 @default.
- W2165624684 hasAuthorship W2165624684A5028315546 @default.
- W2165624684 hasAuthorship W2165624684A5073337287 @default.
- W2165624684 hasAuthorship W2165624684A5089807785 @default.
- W2165624684 hasConcept C126322002 @default.
- W2165624684 hasConcept C134018914 @default.
- W2165624684 hasConcept C142724271 @default.
- W2165624684 hasConcept C143228043 @default.
- W2165624684 hasConcept C168563851 @default.
- W2165624684 hasConcept C187785154 @default.
- W2165624684 hasConcept C204787440 @default.
- W2165624684 hasConcept C27081682 @default.
- W2165624684 hasConcept C2776042228 @default.
- W2165624684 hasConcept C2778720950 @default.
- W2165624684 hasConcept C2779058012 @default.
- W2165624684 hasConcept C71315377 @default.
- W2165624684 hasConcept C71924100 @default.
- W2165624684 hasConceptScore W2165624684C126322002 @default.
- W2165624684 hasConceptScore W2165624684C134018914 @default.
- W2165624684 hasConceptScore W2165624684C142724271 @default.
- W2165624684 hasConceptScore W2165624684C143228043 @default.
- W2165624684 hasConceptScore W2165624684C168563851 @default.
- W2165624684 hasConceptScore W2165624684C187785154 @default.
- W2165624684 hasConceptScore W2165624684C204787440 @default.
- W2165624684 hasConceptScore W2165624684C27081682 @default.
- W2165624684 hasConceptScore W2165624684C2776042228 @default.
- W2165624684 hasConceptScore W2165624684C2778720950 @default.
- W2165624684 hasConceptScore W2165624684C2779058012 @default.
- W2165624684 hasConceptScore W2165624684C71315377 @default.
- W2165624684 hasConceptScore W2165624684C71924100 @default.
- W2165624684 hasLocation W21656246841 @default.
- W2165624684 hasLocation W21656246842 @default.
- W2165624684 hasOpenAccess W2165624684 @default.
- W2165624684 hasPrimaryLocation W21656246841 @default.
- W2165624684 hasRelatedWork W1566419909 @default.
- W2165624684 hasRelatedWork W1996116232 @default.
- W2165624684 hasRelatedWork W2014724895 @default.
- W2165624684 hasRelatedWork W2023858769 @default.
- W2165624684 hasRelatedWork W2043899786 @default.
- W2165624684 hasRelatedWork W2083415808 @default.
- W2165624684 hasRelatedWork W2090757166 @default.
- W2165624684 hasRelatedWork W2099602943 @default.
- W2165624684 hasRelatedWork W2112207893 @default.
- W2165624684 hasRelatedWork W2157714373 @default.
- W2165624684 isParatext "false" @default.
- W2165624684 isRetracted "false" @default.
- W2165624684 magId "2165624684" @default.
- W2165624684 workType "article" @default.