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- W2165655582 abstract "The effects of endothelin-1 were studied in vitro on neurons in the hamster submandibular ganglion, using the intracellular microelectrode technique. Endothelin (1μM) caused a depolarization (5.5±1.2mV) followed by a hyperpolarization (8.5±2.8mV) of the membrane potential. Membrane conductance was increased during the endothelininduced depolarization and was decreased during the endothelin-induced hyperpolarization. The endothelin-induced depolarization was depressed (mean 43.6%) in a Krebs solution containing zero calcium and high magnesium. The results suggested that the predominant component of the depolarization was mediated by calcium ions. The calcium-insensitive component of depolarization was carried by chloride ions. Endothelin-induced slow rhythmic hyperpolarizations were probably induced by a decrease in chloride ion conductance." @default.
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- W2165655582 date "2004-01-01" @default.
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- W2165655582 title "ENDOTHELIN-1-INDUCED DEPOLARIZATION AND HYPERPOLARIZATION IN SUBMANDIBULAR GANGLION NEURONS" @default.
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- W2165655582 doi "https://doi.org/10.2209/tdcpublication.45.189" @default.
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