FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165725306> ?p ?o ?g. }

• W2165725306 endingPage "6" @default.
• W2165725306 startingPage "341" @default.
• W2165725306 abstract "Thyroid hormones affect gastric acid secretion. As the mechanism of this effect has not been fully known, in this experimental study the isolated gastric acid secretion of hypothyroid and hyperthyroid rats were compared with control group by the administration of different doses of pentagastrin, histamine and carbachol as gastric acid secretion stimulators.This study was carried out in Ahwaz University of Medical Sciences, Ahwaz, Iran in the year 2000. Each group were consisted of 8 rats (N-mari) of both sexes with a mean weight of 246 +/- 5 grams. Hypothyroid and hyperthyroid states were induced respectively by adding methimazole (500 mg/liter) for 20 days and thyroxin (500 microg/liter) for 35 days in animals drinking water. After general anesthesia, by intraperitoneal injection of sodium thiopental (50 mg/kg body weight), celiotomy was carried out quickly. The end of esophagus was tied and a silicon tube (2-2.5 mm) was entered into the stomach via duodenum and fasted in pylor region. The stomach was isolated by cutting the esophagus proximal to the tied region and the proximal part of duodenum and put into cold serous solution. After washing the serous and mucus surfaces by serous and mucus solutions, the stomach was transferred immediately to a tissue bath containing warm serous solution (V= 40 ml, T= 37 degrees C). Gastric acid secretion in isolated stomach stimulated by pentagastrin, carbachol and histamine was measured by wash out technique and automatic titrator. Moreover, to study the effect of thyroid hormones on gastric acid secretion a number of dose-dependent experiments after the administration of different doses of histamine (50, 100, 150, 200 micromol), carbachol (50, 100, 150, 200 micromol), and pentagastrin (30, 60, 90, 120 ug/kg body weight) were performed.Both basal and histamine, carbachol, pentagastrin stimulated-acid secretion decreased and increased in hypothyroid and hyperthyroid groups compared with control group.It seems that thyroid hormones have not exert their effects by changing the cholinergic, gastrin and histamine receptors but probably by alerting the number or size of the secretory cells in stomach." @default.
• W2165725306 created "2016-06-24" @default.
• W2165725306 creator A5002324737 @default.
• W2165725306 creator A5003392368 @default.
• W2165725306 creator A5023871400 @default.
• W2165725306 creator A5088874168 @default.
• W2165725306 date "2003-04-01" @default.
• W2165725306 modified "2023-10-18" @default.
• W2165725306 title "Effects of thyroid hormones on basal and stimulated gastric acid secretion due to histamine, carbachol and pentagastrin in rats." @default.
• W2165725306 cites W130330389 @default.
• W2165725306 cites W1865924587 @default.
• W2165725306 cites W1968215660 @default.
• W2165725306 cites W1979410451 @default.
• W2165725306 cites W1984685418 @default.
• W2165725306 cites W1995959790 @default.
• W2165725306 cites W2008871122 @default.
• W2165725306 cites W2022750331 @default.
• W2165725306 cites W2049073723 @default.
• W2165725306 cites W2054297906 @default.
• W2165725306 cites W2059116031 @default.
• W2165725306 cites W2066507264 @default.
• W2165725306 cites W2075729269 @default.
• W2165725306 cites W2088104087 @default.
• W2165725306 cites W2098990824 @default.
• W2165725306 cites W2113625902 @default.
• W2165725306 cites W2115400113 @default.
• W2165725306 cites W2148023044 @default.
• W2165725306 cites W2154824522 @default.
• W2165725306 cites W2160328850 @default.
• W2165725306 cites W2179872398 @default.
• W2165725306 cites W2184800394 @default.
• W2165725306 cites W2254481419 @default.
• W2165725306 cites W2280262299 @default.
• W2165725306 cites W2310885743 @default.
• W2165725306 cites W2337078160 @default.
• W2165725306 cites W2407709156 @default.
• W2165725306 cites W2408461146 @default.
• W2165725306 cites W2414503004 @default.
• W2165725306 cites W2417248700 @default.
• W2165725306 cites W2016145801 @default.
• W2165725306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12754530" @default.
• W2165725306 hasPublicationYear "2003" @default.
• W2165725306 type Work @default.
• W2165725306 sameAs 2165725306 @default.
• W2165725306 citedByCount "7" @default.
• W2165725306 countsByYear W21657253062020 @default.
• W2165725306 crossrefType "journal-article" @default.
• W2165725306 hasAuthorship W2165725306A5002324737 @default.
• W2165725306 hasAuthorship W2165725306A5003392368 @default.
• W2165725306 hasAuthorship W2165725306A5023871400 @default.
• W2165725306 hasAuthorship W2165725306A5088874168 @default.
• W2165725306 hasConcept C1122143 @default.
• W2165725306 hasConcept C126322002 @default.
• W2165725306 hasConcept C134018914 @default.
• W2165725306 hasConcept C150173356 @default.
• W2165725306 hasConcept C24998067 @default.
• W2165725306 hasConcept C2776809568 @default.
• W2165725306 hasConcept C2777504413 @default.
• W2165725306 hasConcept C2778988552 @default.
• W2165725306 hasConcept C2779377912 @default.
• W2165725306 hasConcept C2779422922 @default.
• W2165725306 hasConcept C526584372 @default.
• W2165725306 hasConcept C71924100 @default.
• W2165725306 hasConceptScore W2165725306C1122143 @default.
• W2165725306 hasConceptScore W2165725306C126322002 @default.
• W2165725306 hasConceptScore W2165725306C134018914 @default.
• W2165725306 hasConceptScore W2165725306C150173356 @default.
• W2165725306 hasConceptScore W2165725306C24998067 @default.
• W2165725306 hasConceptScore W2165725306C2776809568 @default.
• W2165725306 hasConceptScore W2165725306C2777504413 @default.
• W2165725306 hasConceptScore W2165725306C2778988552 @default.
• W2165725306 hasConceptScore W2165725306C2779377912 @default.
• W2165725306 hasConceptScore W2165725306C2779422922 @default.
• W2165725306 hasConceptScore W2165725306C526584372 @default.
• W2165725306 hasConceptScore W2165725306C71924100 @default.
• W2165725306 hasIssue "4" @default.
• W2165725306 hasLocation W21657253061 @default.
• W2165725306 hasOpenAccess W2165725306 @default.
• W2165725306 hasPrimaryLocation W21657253061 @default.
• W2165725306 hasRelatedWork W1966448777 @default.
• W2165725306 hasRelatedWork W1992788434 @default.
• W2165725306 hasRelatedWork W1999581759 @default.
• W2165725306 hasRelatedWork W2053006972 @default.
• W2165725306 hasRelatedWork W2063428427 @default.
• W2165725306 hasRelatedWork W2128755245 @default.
• W2165725306 hasRelatedWork W2165725306 @default.
• W2165725306 hasRelatedWork W2400561641 @default.
• W2165725306 hasRelatedWork W2417235576 @default.
• W2165725306 hasRelatedWork W2577312838 @default.
• W2165725306 hasVolume "24" @default.
• W2165725306 isParatext "false" @default.
• W2165725306 isRetracted "false" @default.
• W2165725306 magId "2165725306" @default.
• W2165725306 workType "article" @default.