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• W2165774810 abstract "<b>Introduction:</b> Hypoxemia during airway management remains an important cause of morbidity and mortality. Oxygenation during intubation via nasal prongs may prevent critical desaturations (Anesthesiology 1988, J Korean Med Sci 1998). We evaluated the effectiveness of oxygen administration via nasal prongs during apneic period following induction of general anesthesia. <b>Methods:</b> We conducted a randomized, controlled, double-blind study in patients without significant cardiac or respiratory disease undergoing elective surgery (age 18-65, ASA I-III). Patients randomly received oxygen via nasal prongs at 0, 5, or 10 L/min. Following preoxygenation, general anesthesia was induced. At 90 seconds after induction, nasal prongs were applied and oxygen was delivered according to the experimental group. At 4.5 minutes post-induction the patients were intubated. <b>Results:</b> The study population consisted of 41 individuals, 14 in the 0 L group, 13 in the 5 L group, and 14 in the 10 L group. Significant difference occurred between the three treatments (p=0.030), across time (p=0.028), and the treatment effect across time (p=0.017). Mean PaO₂was higher in the 10 L group than the 5 L group (p=0.001) and 0 L group at 4 minutes (p=0.004). <b>Conclusion:</b> Apneic oxygenation with 10 L/min compared to 5 L/min via nasal prongs demonstrated delay of desaturation and maintenance of higher PaO₂ levels during elective intubation." @default.
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• W2165774810 date "1998-02-01" @default.
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• W2165774810 title "Adult myeloid leukaemia, geology, and domestic exposure to radon and gamma radiation: a case control study in central Italy" @default.
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• W2165774810 doi "https://doi.org/10.1136/oem.55.2.106" @default.
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