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- W2165820003 abstract "Calorie restriction (CR) is a lifestyle intervention employed to reduce body weight and improve metabolic functions primarily via reduction of ingested carbohydrates and fats. Taste perception is highly related to functional metabolic status and body adiposity. We have previously shown that sweet taste perception diminishes with age; however, relatively little is known about the effects of various lengths of CR upon taste cell morphology and function. We investigated the effects of CR on taste bud morphology and expression of sweet taste-related modulators in 5-, 17-, and 30-month-old rats. In ad libitum (AL) and CR rats, we consistently found the following parameters altered significantly with advancing age: reduction of taste bud size and taste cell numbers per taste bud and reduced expression of sonic hedgehog, type 1 taste receptor 3 (T1r3), α-gustducin, and glucagon-like peptide-1 (GLP-1). In the oldest rats, CR affected a significant reduction of tongue T1r3, GLP-1, and α-gustducin expression compared with age-matched AL rats. Leptin receptor immunopositive cells were elevated in 17- and 30-month-old CR rats compared with age-matched AL rats. These alterations of sweet taste-related modulators, specifically during advanced aging, suggest that sweet taste perception may be altered in response to different lengths of CR." @default.
- W2165820003 created "2016-06-24" @default.
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- W2165820003 date "2013-09-28" @default.
- W2165820003 modified "2023-09-27" @default.
- W2165820003 title "Longitudinal Analysis of Calorie Restriction on Rat Taste Bud Morphology and Expression of Sweet Taste Modulators" @default.
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- W2165820003 cites W1973045418 @default.
- W2165820003 cites W1975625687 @default.
- W2165820003 cites W1976214195 @default.
- W2165820003 cites W1978626582 @default.
- W2165820003 cites W1978966909 @default.
- W2165820003 cites W1982008547 @default.
- W2165820003 cites W1982455282 @default.
- W2165820003 cites W1982457556 @default.
- W2165820003 cites W1996827810 @default.
- W2165820003 cites W1998043974 @default.
- W2165820003 cites W2010251404 @default.
- W2165820003 cites W2012848916 @default.
- W2165820003 cites W2018973834 @default.
- W2165820003 cites W2020053294 @default.
- W2165820003 cites W2023939486 @default.
- W2165820003 cites W2026251382 @default.
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- W2165820003 cites W2034780781 @default.
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- W2165820003 cites W2081923532 @default.
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- W2165820003 cites W2141809387 @default.
- W2165820003 cites W2151566575 @default.
- W2165820003 cites W2151798163 @default.
- W2165820003 cites W2152516819 @default.
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- W2165820003 doi "https://doi.org/10.1093/gerona/glt129" @default.
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