Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165931988> ?p ?o ?g. }
- W2165931988 endingPage "992" @default.
- W2165931988 startingPage "982" @default.
- W2165931988 abstract "In cardiovascular computational physiology the importance of understanding cardiac contraction as a multi-scale process is of paramount importance to understand causality across different scales. Within this study, a multi-scale and multi-physics model of the left ventricle that connects the process of cardiac excitation and contraction from the protein to the organ level is presented in a novel way. The model presented here includes the functional description of a cardiomyocyte (cellular scale), which explains the dynamic behaviour of the calcium concentration within the cell whilst an action potential develops. The cell domain is coupled to a domain that determines the kinetics of the sliding filament mechanism (protein level), which is at the basis of cardiac contraction. These processes are then linked to the generation of muscular force and from there to the generation of pressure inside the ventricle. This multi-scale model presents a coherent and unified way to describe cardiac contraction from the protein to the organ level." @default.
- W2165931988 created "2016-06-24" @default.
- W2165931988 creator A5002800973 @default.
- W2165931988 creator A5013642105 @default.
- W2165931988 creator A5026601290 @default.
- W2165931988 date "2012-10-01" @default.
- W2165931988 modified "2023-09-27" @default.
- W2165931988 title "A multi-physics and multi-scale lumped parameter model of cardiac contraction of the left ventricle: A conceptual model from the protein to the organ scale" @default.
- W2165931988 cites W1499122117 @default.
- W2165931988 cites W1600162423 @default.
- W2165931988 cites W1964430604 @default.
- W2165931988 cites W1966543040 @default.
- W2165931988 cites W1985940938 @default.
- W2165931988 cites W1987584482 @default.
- W2165931988 cites W1993414665 @default.
- W2165931988 cites W2019201408 @default.
- W2165931988 cites W2021622307 @default.
- W2165931988 cites W2028146834 @default.
- W2165931988 cites W2031742432 @default.
- W2165931988 cites W2054260653 @default.
- W2165931988 cites W2060100056 @default.
- W2165931988 cites W2064439175 @default.
- W2165931988 cites W2069051817 @default.
- W2165931988 cites W2074520327 @default.
- W2165931988 cites W2084421529 @default.
- W2165931988 cites W2085437800 @default.
- W2165931988 cites W2099767007 @default.
- W2165931988 cites W2104449065 @default.
- W2165931988 cites W2105757663 @default.
- W2165931988 cites W2107954466 @default.
- W2165931988 cites W2113586457 @default.
- W2165931988 cites W2132561989 @default.
- W2165931988 cites W2132642267 @default.
- W2165931988 cites W2133011107 @default.
- W2165931988 cites W2142046499 @default.
- W2165931988 cites W2144456050 @default.
- W2165931988 cites W2149002598 @default.
- W2165931988 cites W2152611452 @default.
- W2165931988 cites W2155900093 @default.
- W2165931988 cites W2169400659 @default.
- W2165931988 cites W4230472630 @default.
- W2165931988 doi "https://doi.org/10.1016/j.compbiomed.2012.07.010" @default.
- W2165931988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22921613" @default.
- W2165931988 hasPublicationYear "2012" @default.
- W2165931988 type Work @default.
- W2165931988 sameAs 2165931988 @default.
- W2165931988 citedByCount "8" @default.
- W2165931988 countsByYear W21659319882013 @default.
- W2165931988 countsByYear W21659319882014 @default.
- W2165931988 countsByYear W21659319882017 @default.
- W2165931988 crossrefType "journal-article" @default.
- W2165931988 hasAuthorship W2165931988A5002800973 @default.
- W2165931988 hasAuthorship W2165931988A5013642105 @default.
- W2165931988 hasAuthorship W2165931988A5026601290 @default.
- W2165931988 hasConcept C105702510 @default.
- W2165931988 hasConcept C121332964 @default.
- W2165931988 hasConcept C126322002 @default.
- W2165931988 hasConcept C163415756 @default.
- W2165931988 hasConcept C164705383 @default.
- W2165931988 hasConcept C186060115 @default.
- W2165931988 hasConcept C2778755073 @default.
- W2165931988 hasConcept C2778921608 @default.
- W2165931988 hasConcept C2778996579 @default.
- W2165931988 hasConcept C2910288590 @default.
- W2165931988 hasConcept C41008148 @default.
- W2165931988 hasConcept C62520636 @default.
- W2165931988 hasConcept C71924100 @default.
- W2165931988 hasConcept C86803240 @default.
- W2165931988 hasConcept C99398487 @default.
- W2165931988 hasConceptScore W2165931988C105702510 @default.
- W2165931988 hasConceptScore W2165931988C121332964 @default.
- W2165931988 hasConceptScore W2165931988C126322002 @default.
- W2165931988 hasConceptScore W2165931988C163415756 @default.
- W2165931988 hasConceptScore W2165931988C164705383 @default.
- W2165931988 hasConceptScore W2165931988C186060115 @default.
- W2165931988 hasConceptScore W2165931988C2778755073 @default.
- W2165931988 hasConceptScore W2165931988C2778921608 @default.
- W2165931988 hasConceptScore W2165931988C2778996579 @default.
- W2165931988 hasConceptScore W2165931988C2910288590 @default.
- W2165931988 hasConceptScore W2165931988C41008148 @default.
- W2165931988 hasConceptScore W2165931988C62520636 @default.
- W2165931988 hasConceptScore W2165931988C71924100 @default.
- W2165931988 hasConceptScore W2165931988C86803240 @default.
- W2165931988 hasConceptScore W2165931988C99398487 @default.
- W2165931988 hasIssue "10" @default.
- W2165931988 hasLocation W21659319881 @default.
- W2165931988 hasLocation W21659319882 @default.
- W2165931988 hasOpenAccess W2165931988 @default.
- W2165931988 hasPrimaryLocation W21659319881 @default.
- W2165931988 hasRelatedWork W11150561 @default.
- W2165931988 hasRelatedWork W1977297164 @default.
- W2165931988 hasRelatedWork W2018687056 @default.
- W2165931988 hasRelatedWork W2036850627 @default.
- W2165931988 hasRelatedWork W2107302341 @default.
- W2165931988 hasRelatedWork W2165931988 @default.
- W2165931988 hasRelatedWork W2418950109 @default.
- W2165931988 hasRelatedWork W2474149440 @default.
- W2165931988 hasRelatedWork W3151559333 @default.