FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2165995004> ?p ?o ?g. }

• W2165995004 endingPage "1082" @default.
• W2165995004 startingPage "1073" @default.
• W2165995004 abstract "The protandrous black porgy, Acanthopagrus schlegeli, has a striking life cycle with sex differentiation at the juvenile stage, mono-male development, and male-to-female sex change (with vitellogenic oocytes) at age 3 yr. In the present study, we investigated the possible roles of wnt4 in gonadal development in a nonmammalian model organism (protandrous black porgy), especially in relation to sex differentiation, ovarian growth, and sex change. Fish of various ages were treated with estradiol (E2) or aromatase inhibitor (AI) to determine whether manipulation of the hormonal environment had an effect on these processes. Furthermore, a natural sex change (≥2-yr-old fish) and a nonchemical method to induce an early sex change (≥1-yr-old fish) via the removal of testicular tissue were examined in this study. We present herein an integrative immunohistochemical, cellular, and molecular data set describing these phenomena. During gonadal sex differentiation, no increase in wnt4 expression was detected. A profile of increased wnt4 expression and decreased cyp19a1a expression was associated with ovarian growth (proliferation of oogonia and development of ovarian lamellae) in ≥1-yr-old fish. Both E2 and AI induced an increase in wnt4 transcripts and resulted in ovarian development in ≥0-yr-old and ≥1-yr-old fish. Increased wnt4 transcripts were found in ovarian tissue undergoing development from primary oocytes to vitellogenic oocytes during the natural sex change in ≥2-yr-old fish. Removal of testicular tissue in ≥1-yr-old fish resulted in successful early sex change (with vitellogenic oocytes) 6 mo after the excision. During the process of the early sex change (3 mo after testis excision), the fish ovary became active and had increased diameter of the primary oocytes; this was in accord with increased ovarian wnt4 expression but not sf1, foxl2, and genes in the steroidogenic pathway, including cyp19a1a. Wnt4 staining further confirmed the profile of wnt4 expression associated with ovarian development. The results of the present study suggest that wnt4 has important roles in late ovarian growth (e.g., oogonia proliferation and structure of ovarian lamellae) and the natural sex change (vitellogenic oocytes) in the protandrous black porgy." @default.
• W2165995004 created "2016-06-24" @default.
• W2165995004 creator A5017598017 @default.
• W2165995004 creator A5071756225 @default.
• W2165995004 date "2009-12-01" @default.
• W2165995004 modified "2023-09-24" @default.
• W2165995004 title "wnt4 Is Associated with the Development of Ovarian Tissue in the Protandrous Black Porgy, Acanthopagrus schlegeli1" @default.
• W2165995004 cites W1498970130 @default.
• W2165995004 cites W1586715008 @default.
• W2165995004 cites W1964315134 @default.
• W2165995004 cites W1965850432 @default.
• W2165995004 cites W1966396293 @default.
• W2165995004 cites W1975161421 @default.
• W2165995004 cites W1991026868 @default.
• W2165995004 cites W1992296314 @default.
• W2165995004 cites W2000113246 @default.
• W2165995004 cites W2001459984 @default.
• W2165995004 cites W2011617862 @default.
• W2165995004 cites W2018708589 @default.
• W2165995004 cites W2020617101 @default.
• W2165995004 cites W2021163527 @default.
• W2165995004 cites W2021544762 @default.
• W2165995004 cites W2026454378 @default.
• W2165995004 cites W2029841586 @default.
• W2165995004 cites W2034650806 @default.
• W2165995004 cites W2038649350 @default.
• W2165995004 cites W2042446343 @default.
• W2165995004 cites W2046104690 @default.
• W2165995004 cites W2046935125 @default.
• W2165995004 cites W2070430623 @default.
• W2165995004 cites W2077427712 @default.
• W2165995004 cites W2085246071 @default.
• W2165995004 cites W2087868680 @default.
• W2165995004 cites W2091123620 @default.
• W2165995004 cites W2092379587 @default.
• W2165995004 cites W2106235028 @default.
• W2165995004 cites W2109458831 @default.
• W2165995004 cites W2111623931 @default.
• W2165995004 cites W2113265133 @default.
• W2165995004 cites W2120682981 @default.
• W2165995004 cites W2123046711 @default.
• W2165995004 cites W2148663279 @default.
• W2165995004 cites W2157630690 @default.
• W2165995004 cites W2171410951 @default.
• W2165995004 cites W2171932920 @default.
• W2165995004 doi "https://doi.org/10.1095/biolreprod.109.077362" @default.
• W2165995004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19605791" @default.
• W2165995004 hasPublicationYear "2009" @default.
• W2165995004 type Work @default.
• W2165995004 sameAs 2165995004 @default.
• W2165995004 citedByCount "66" @default.
• W2165995004 countsByYear W21659950042012 @default.
• W2165995004 countsByYear W21659950042013 @default.
• W2165995004 countsByYear W21659950042014 @default.
• W2165995004 countsByYear W21659950042015 @default.
• W2165995004 countsByYear W21659950042016 @default.
• W2165995004 countsByYear W21659950042017 @default.
• W2165995004 countsByYear W21659950042018 @default.
• W2165995004 countsByYear W21659950042019 @default.
• W2165995004 countsByYear W21659950042020 @default.
• W2165995004 countsByYear W21659950042021 @default.
• W2165995004 countsByYear W21659950042022 @default.
• W2165995004 countsByYear W21659950042023 @default.
• W2165995004 crossrefType "journal-article" @default.
• W2165995004 hasAuthorship W2165995004A5017598017 @default.
• W2165995004 hasAuthorship W2165995004A5071756225 @default.
• W2165995004 hasBestOaLocation W21659950041 @default.
• W2165995004 hasConcept C104317684 @default.
• W2165995004 hasConcept C126322002 @default.
• W2165995004 hasConcept C134018914 @default.
• W2165995004 hasConcept C137487509 @default.
• W2165995004 hasConcept C150194340 @default.
• W2165995004 hasConcept C16685009 @default.
• W2165995004 hasConcept C196843134 @default.
• W2165995004 hasConcept C2776290222 @default.
• W2165995004 hasConcept C2776690073 @default.
• W2165995004 hasConcept C2778324911 @default.
• W2165995004 hasConcept C2781430442 @default.
• W2165995004 hasConcept C2781471917 @default.
• W2165995004 hasConcept C2909208804 @default.
• W2165995004 hasConcept C505870484 @default.
• W2165995004 hasConcept C54355233 @default.
• W2165995004 hasConcept C56366318 @default.
• W2165995004 hasConcept C63405245 @default.
• W2165995004 hasConcept C71924100 @default.
• W2165995004 hasConcept C86803240 @default.
• W2165995004 hasConcept C90856448 @default.
• W2165995004 hasConcept C95444343 @default.
• W2165995004 hasConceptScore W2165995004C104317684 @default.
• W2165995004 hasConceptScore W2165995004C126322002 @default.
• W2165995004 hasConceptScore W2165995004C134018914 @default.
• W2165995004 hasConceptScore W2165995004C137487509 @default.
• W2165995004 hasConceptScore W2165995004C150194340 @default.
• W2165995004 hasConceptScore W2165995004C16685009 @default.
• W2165995004 hasConceptScore W2165995004C196843134 @default.
• W2165995004 hasConceptScore W2165995004C2776290222 @default.
• W2165995004 hasConceptScore W2165995004C2776690073 @default.
• W2165995004 hasConceptScore W2165995004C2778324911 @default.

• next