Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166011196> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2166011196 endingPage "246" @default.
- W2166011196 startingPage "237" @default.
- W2166011196 abstract "Background and Objectives G‐CSF mobilized peripheral blood stem/progenitor cells are frequently used for allogeneic transplantation. Available manual apheresis systems generate stem cell products of consistently high quality. Short‐comings include need for continuous interface monitoring/adjustment, interface instability in donors with inconsistent blood flow, high collection variability, high platelet loss, and failure to electronically document apheresis parameters. Material and Methods A fundamentally different, novel apheresis system, Spectra Optia v.5·0, featuring optical sensors, which provide real‐time automatic interface and product collect line control, and newly developed tubing sets, was designed to address these short‐comings. In a prospective validation study, 30 healthy volunteer stem cell donors were subjected to apheresis with Spectra Optia to test feasibility and effectiveness. Results were compared to 608 historic first‐day allogeneic aphereses with COBE Spectra MNC. Results Usability and function of automatic interface control of Spectra Optia were good. Most collection parameters, including collection efficiency and product size, were similar. Cells were viable and provided timely engraftment. Platelet loss with Spectra Optia was 25% less than with COBE Spectra MNC. Products contained fewer erythrocytes, but more granulocytes. Conclusion The automatic apheresis system Spectra Optia is functional and user‐friendly. Thus Spectra Optia aphereses are associated with similar, and equally variable, collection efficiencies as COBE Spectra MNC." @default.
- W2166011196 created "2016-06-24" @default.
- W2166011196 creator A5025072735 @default.
- W2166011196 creator A5063233840 @default.
- W2166011196 creator A5073921472 @default.
- W2166011196 creator A5081650438 @default.
- W2166011196 creator A5088797832 @default.
- W2166011196 date "2011-04-25" @default.
- W2166011196 modified "2023-10-15" @default.
- W2166011196 title "Mobilized allogeneic peripheral stem/progenitor cell apheresis with Spectra Optia v.5·0, a novel, automatic interface-controlled apheresis system: results from the first feasibility trial" @default.
- W2166011196 cites W1964551219 @default.
- W2166011196 cites W1981437109 @default.
- W2166011196 cites W1982214476 @default.
- W2166011196 cites W1982986673 @default.
- W2166011196 cites W2007342088 @default.
- W2166011196 cites W2007891374 @default.
- W2166011196 cites W2012053567 @default.
- W2166011196 cites W2032497904 @default.
- W2166011196 cites W2034768868 @default.
- W2166011196 cites W2038106134 @default.
- W2166011196 cites W2039714185 @default.
- W2166011196 cites W2040582241 @default.
- W2166011196 cites W2057569435 @default.
- W2166011196 cites W2059860297 @default.
- W2166011196 cites W2067189365 @default.
- W2166011196 cites W2087975071 @default.
- W2166011196 cites W2100496841 @default.
- W2166011196 cites W2112692705 @default.
- W2166011196 cites W2149009249 @default.
- W2166011196 cites W2157117178 @default.
- W2166011196 cites W2337680764 @default.
- W2166011196 cites W3212182878 @default.
- W2166011196 doi "https://doi.org/10.1111/j.1423-0410.2011.01484.x" @default.
- W2166011196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21517897" @default.
- W2166011196 hasPublicationYear "2011" @default.
- W2166011196 type Work @default.
- W2166011196 sameAs 2166011196 @default.
- W2166011196 citedByCount "49" @default.
- W2166011196 countsByYear W21660111962012 @default.
- W2166011196 countsByYear W21660111962013 @default.
- W2166011196 countsByYear W21660111962014 @default.
- W2166011196 countsByYear W21660111962015 @default.
- W2166011196 countsByYear W21660111962016 @default.
- W2166011196 countsByYear W21660111962017 @default.
- W2166011196 countsByYear W21660111962018 @default.
- W2166011196 countsByYear W21660111962019 @default.
- W2166011196 countsByYear W21660111962020 @default.
- W2166011196 countsByYear W21660111962023 @default.
- W2166011196 crossrefType "journal-article" @default.
- W2166011196 hasAuthorship W2166011196A5025072735 @default.
- W2166011196 hasAuthorship W2166011196A5063233840 @default.
- W2166011196 hasAuthorship W2166011196A5073921472 @default.
- W2166011196 hasAuthorship W2166011196A5081650438 @default.
- W2166011196 hasAuthorship W2166011196A5088797832 @default.
- W2166011196 hasConcept C126322002 @default.
- W2166011196 hasConcept C126894567 @default.
- W2166011196 hasConcept C136229726 @default.
- W2166011196 hasConcept C141071460 @default.
- W2166011196 hasConcept C201750760 @default.
- W2166011196 hasConcept C2776738589 @default.
- W2166011196 hasConcept C28328180 @default.
- W2166011196 hasConcept C2911091166 @default.
- W2166011196 hasConcept C54355233 @default.
- W2166011196 hasConcept C71924100 @default.
- W2166011196 hasConcept C86803240 @default.
- W2166011196 hasConcept C89560881 @default.
- W2166011196 hasConceptScore W2166011196C126322002 @default.
- W2166011196 hasConceptScore W2166011196C126894567 @default.
- W2166011196 hasConceptScore W2166011196C136229726 @default.
- W2166011196 hasConceptScore W2166011196C141071460 @default.
- W2166011196 hasConceptScore W2166011196C201750760 @default.
- W2166011196 hasConceptScore W2166011196C2776738589 @default.
- W2166011196 hasConceptScore W2166011196C28328180 @default.
- W2166011196 hasConceptScore W2166011196C2911091166 @default.
- W2166011196 hasConceptScore W2166011196C54355233 @default.
- W2166011196 hasConceptScore W2166011196C71924100 @default.
- W2166011196 hasConceptScore W2166011196C86803240 @default.
- W2166011196 hasConceptScore W2166011196C89560881 @default.
- W2166011196 hasIssue "3" @default.
- W2166011196 hasLocation W21660111961 @default.
- W2166011196 hasLocation W21660111962 @default.
- W2166011196 hasOpenAccess W2166011196 @default.
- W2166011196 hasPrimaryLocation W21660111961 @default.
- W2166011196 hasRelatedWork W1982214476 @default.
- W2166011196 hasRelatedWork W2000793674 @default.
- W2166011196 hasRelatedWork W2062500024 @default.
- W2166011196 hasRelatedWork W2071719482 @default.
- W2166011196 hasRelatedWork W2079426199 @default.
- W2166011196 hasRelatedWork W2330128180 @default.
- W2166011196 hasRelatedWork W249915236 @default.
- W2166011196 hasRelatedWork W3000384862 @default.
- W2166011196 hasRelatedWork W4205608766 @default.
- W2166011196 hasRelatedWork W4232556345 @default.
- W2166011196 hasVolume "101" @default.
- W2166011196 isParatext "false" @default.
- W2166011196 isRetracted "false" @default.
- W2166011196 magId "2166011196" @default.
- W2166011196 workType "article" @default.