FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166108335> ?p ?o ?g. }

• W2166108335 endingPage "2503" @default.
• W2166108335 startingPage "2496" @default.
• W2166108335 abstract "Isolated uterine vascular beds from virgin and pregnant rats were used to assess vascular reactivity and the ability of nitric oxide (NO), prostanoids and endothelium-derived hyperpolarizing factor (EDHF) to modulate these responses. One uterine horn from female rats in each oestrous cycle day and gestation day 17 was removed and perfused with physiological saline solution. Tone was induced with cirazoline (1 micromol/l), and concentration-response curves to acetylcholine (ACh) generated. Responsiveness to ACh was tested in the presence of N-nitro-L-arginine (L-NA), ibuprofen (IBU) and tetrabutylammonium (TBA), to inhibit NO synthase, cyclo-oxygenase and K+ channels respectively. Cirazoline-induced tone was smaller in the pregnant compared with the proestrous group. Sensitivity to ACh was cycle day and pregnancy dependent with pregnant > dioestrous day-1 > dioestrous day-2 > proestrous and oestrous. L-NA shifted the curve to the right in all groups except dioestrous day-1. IBU inhibited the ACh response in the pregnant group only. TBA virtually abolished the response in all groups. These results suggest that in the uterine vascular bed from pregnant rats, EDHF, along with NO and a dilator prostanoid mediate ACh-induced dilatation. In contrast, in the dioestrous day-1 group, only EDHF seems to be released by ACh in this vascular bed. In the oestrous, dioestrous day-2 and proestrous groups, ACh releases both EDHF and NO." @default.
• W2166108335 created "2016-06-24" @default.
• W2166108335 creator A5023563762 @default.
• W2166108335 creator A5045999974 @default.
• W2166108335 creator A5077409895 @default.
• W2166108335 date "2000-12-01" @default.
• W2166108335 modified "2023-09-25" @default.
• W2166108335 title "Oestrous cycle and pregnancy alter the reactivity of the rat uterine vasculature" @default.
• W2166108335 cites W1876194350 @default.
• W2166108335 cites W1963945003 @default.
• W2166108335 cites W1976432295 @default.
• W2166108335 cites W1992753498 @default.
• W2166108335 cites W2008717935 @default.
• W2166108335 cites W2014727568 @default.
• W2166108335 cites W2023726214 @default.
• W2166108335 cites W2031639717 @default.
• W2166108335 cites W2061137068 @default.
• W2166108335 cites W2070083516 @default.
• W2166108335 cites W2073244888 @default.
• W2166108335 cites W2084158921 @default.
• W2166108335 cites W2085367013 @default.
• W2166108335 cites W2087004980 @default.
• W2166108335 cites W2089150892 @default.
• W2166108335 cites W2093603461 @default.
• W2166108335 cites W2094012728 @default.
• W2166108335 cites W2096678729 @default.
• W2166108335 cites W2105771239 @default.
• W2166108335 cites W2109739904 @default.
• W2166108335 cites W2112130800 @default.
• W2166108335 cites W2143751722 @default.
• W2166108335 cites W2168463231 @default.
• W2166108335 cites W2189232363 @default.
• W2166108335 cites W2326417371 @default.
• W2166108335 cites W2398681871 @default.
• W2166108335 cites W2401486916 @default.
• W2166108335 cites W2897519809 @default.
• W2166108335 cites W4230830257 @default.
• W2166108335 cites W4293586669 @default.
• W2166108335 doi "https://doi.org/10.1093/humrep/15.12.2496" @default.
• W2166108335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11098017" @default.
• W2166108335 hasPublicationYear "2000" @default.
• W2166108335 type Work @default.
• W2166108335 sameAs 2166108335 @default.
• W2166108335 citedByCount "26" @default.
• W2166108335 countsByYear W21661083352012 @default.
• W2166108335 countsByYear W21661083352013 @default.
• W2166108335 countsByYear W21661083352014 @default.
• W2166108335 countsByYear W21661083352015 @default.
• W2166108335 countsByYear W21661083352018 @default.
• W2166108335 countsByYear W21661083352019 @default.
• W2166108335 countsByYear W21661083352020 @default.
• W2166108335 countsByYear W21661083352021 @default.
• W2166108335 crossrefType "journal-article" @default.
• W2166108335 hasAuthorship W2166108335A5023563762 @default.
• W2166108335 hasAuthorship W2166108335A5045999974 @default.
• W2166108335 hasAuthorship W2166108335A5077409895 @default.
• W2166108335 hasBestOaLocation W21661083351 @default.
• W2166108335 hasConcept C126322002 @default.
• W2166108335 hasConcept C134018914 @default.
• W2166108335 hasConcept C185592680 @default.
• W2166108335 hasConcept C1998276 @default.
• W2166108335 hasConcept C2775910092 @default.
• W2166108335 hasConcept C2777622882 @default.
• W2166108335 hasConcept C2778010969 @default.
• W2166108335 hasConcept C2778227567 @default.
• W2166108335 hasConcept C2778266237 @default.
• W2166108335 hasConcept C2779066055 @default.
• W2166108335 hasConcept C2779234561 @default.
• W2166108335 hasConcept C2780664492 @default.
• W2166108335 hasConcept C2781207646 @default.
• W2166108335 hasConcept C46973012 @default.
• W2166108335 hasConcept C519581460 @default.
• W2166108335 hasConcept C54355233 @default.
• W2166108335 hasConcept C71924100 @default.
• W2166108335 hasConcept C86803240 @default.
• W2166108335 hasConceptScore W2166108335C126322002 @default.
• W2166108335 hasConceptScore W2166108335C134018914 @default.
• W2166108335 hasConceptScore W2166108335C185592680 @default.
• W2166108335 hasConceptScore W2166108335C1998276 @default.
• W2166108335 hasConceptScore W2166108335C2775910092 @default.
• W2166108335 hasConceptScore W2166108335C2777622882 @default.
• W2166108335 hasConceptScore W2166108335C2778010969 @default.
• W2166108335 hasConceptScore W2166108335C2778227567 @default.
• W2166108335 hasConceptScore W2166108335C2778266237 @default.
• W2166108335 hasConceptScore W2166108335C2779066055 @default.
• W2166108335 hasConceptScore W2166108335C2779234561 @default.
• W2166108335 hasConceptScore W2166108335C2780664492 @default.
• W2166108335 hasConceptScore W2166108335C2781207646 @default.
• W2166108335 hasConceptScore W2166108335C46973012 @default.
• W2166108335 hasConceptScore W2166108335C519581460 @default.
• W2166108335 hasConceptScore W2166108335C54355233 @default.
• W2166108335 hasConceptScore W2166108335C71924100 @default.
• W2166108335 hasConceptScore W2166108335C86803240 @default.
• W2166108335 hasIssue "12" @default.
• W2166108335 hasLocation W21661083351 @default.
• W2166108335 hasLocation W21661083352 @default.
• W2166108335 hasOpenAccess W2166108335 @default.
• W2166108335 hasPrimaryLocation W21661083351 @default.

• next