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- W2166113462 endingPage "162" @default.
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- W2166113462 abstract "Bacteria have been widely used as starter cultures in the food industry, notably for the fermentation of milk into dairy products such as cheese and yogurt. Lactic acid bacteria used in food manufacturing, such as lactobacilli, lactococci, streptococci, Leuconostoc, pediococci, and bifidobacteria, are selectively formulated based on functional characteristics that provide idiosyncratic flavor and texture attributes, as well as their ability to withstand processing and manufacturing conditions. Unfortunately, given frequent viral exposure in industrial environments, starter culture selection and development rely on defense systems that provide resistance against bacteriophage predation, including restriction-modification, abortive infection, and recently discovered CRISPRs (clustered regularly interspaced short palindromic repeats). CRISPRs, together with CRISPR-associated genes (cas), form the CRISPR/Cas immune system, which provides adaptive immunity against phages and invasive genetic elements. The immunization process is based on the incorporation of short DNA sequences from virulent phages into the CRISPR locus. Subsequently, CRISPR transcripts are processed into small interfering RNAs that guide a multifunctional protein complex to recognize and cleave matching foreign DNA. Hypervariable CRISPR loci provide insights into the phage and host population dynamics, and new avenues for enhanced phage resistance and genetic typing and tagging of industrial strains." @default.
- W2166113462 created "2016-06-24" @default.
- W2166113462 creator A5008191157 @default.
- W2166113462 creator A5085166852 @default.
- W2166113462 date "2012-04-10" @default.
- W2166113462 modified "2023-10-14" @default.
- W2166113462 title "CRISPR: New Horizons in Phage Resistance and Strain Identification" @default.
- W2166113462 cites W1495583714 @default.
- W2166113462 cites W1525072270 @default.
- W2166113462 cites W1563631267 @default.
- W2166113462 cites W1577973179 @default.
- W2166113462 cites W1926535993 @default.
- W2166113462 cites W1941776143 @default.
- W2166113462 cites W1971115321 @default.
- W2166113462 cites W1977531433 @default.
- W2166113462 cites W1978094899 @default.
- W2166113462 cites W1984164827 @default.
- W2166113462 cites W1986171241 @default.
- W2166113462 cites W1986718765 @default.
- W2166113462 cites W1989568784 @default.
- W2166113462 cites W1990487336 @default.
- W2166113462 cites W1990570898 @default.
- W2166113462 cites W1995614275 @default.
- W2166113462 cites W1995867192 @default.
- W2166113462 cites W2004311938 @default.
- W2166113462 cites W2007153971 @default.
- W2166113462 cites W2008665793 @default.
- W2166113462 cites W2008790072 @default.
- W2166113462 cites W2010986636 @default.
- W2166113462 cites W2013045685 @default.
- W2166113462 cites W2016992644 @default.
- W2166113462 cites W2017721099 @default.
- W2166113462 cites W2019197162 @default.
- W2166113462 cites W2022480099 @default.
- W2166113462 cites W2023186109 @default.
- W2166113462 cites W2027591298 @default.
- W2166113462 cites W2029647341 @default.
- W2166113462 cites W2034048377 @default.
- W2166113462 cites W2038838144 @default.
- W2166113462 cites W2039375385 @default.
- W2166113462 cites W2046985302 @default.
- W2166113462 cites W2047032063 @default.
- W2166113462 cites W2049420497 @default.
- W2166113462 cites W2051133017 @default.
- W2166113462 cites W2051745967 @default.
- W2166113462 cites W2052192736 @default.
- W2166113462 cites W2053019594 @default.
- W2166113462 cites W2057092463 @default.
- W2166113462 cites W2057964816 @default.
- W2166113462 cites W2059901968 @default.
- W2166113462 cites W2060573994 @default.
- W2166113462 cites W2061555533 @default.
- W2166113462 cites W2062008243 @default.
- W2166113462 cites W2062280978 @default.
- W2166113462 cites W2062569898 @default.
- W2166113462 cites W2063376698 @default.
- W2166113462 cites W2067853474 @default.
- W2166113462 cites W2074024632 @default.
- W2166113462 cites W2074136235 @default.
- W2166113462 cites W2074478813 @default.
- W2166113462 cites W2074862753 @default.
- W2166113462 cites W2077190448 @default.
- W2166113462 cites W2077724889 @default.
- W2166113462 cites W2078115022 @default.
- W2166113462 cites W2081209254 @default.
- W2166113462 cites W2085436536 @default.
- W2166113462 cites W2085992785 @default.
- W2166113462 cites W2086155031 @default.
- W2166113462 cites W2088128050 @default.
- W2166113462 cites W2088154229 @default.
- W2166113462 cites W2088817509 @default.
- W2166113462 cites W2090176539 @default.
- W2166113462 cites W2096162460 @default.
- W2166113462 cites W2097155272 @default.
- W2166113462 cites W2098481097 @default.
- W2166113462 cites W2098508116 @default.
- W2166113462 cites W2100226515 @default.
- W2166113462 cites W2101788140 @default.
- W2166113462 cites W2101983500 @default.
- W2166113462 cites W2102827392 @default.
- W2166113462 cites W2104549970 @default.
- W2166113462 cites W2104910883 @default.
- W2166113462 cites W2106900261 @default.
- W2166113462 cites W2108101601 @default.
- W2166113462 cites W2108563020 @default.
- W2166113462 cites W2112261922 @default.
- W2166113462 cites W2112295554 @default.
- W2166113462 cites W2116106444 @default.
- W2166113462 cites W2116924408 @default.
- W2166113462 cites W2118665281 @default.
- W2166113462 cites W2118746294 @default.
- W2166113462 cites W2119043925 @default.
- W2166113462 cites W2120503144 @default.
- W2166113462 cites W2123965484 @default.
- W2166113462 cites W2125853124 @default.
- W2166113462 cites W2126660268 @default.
- W2166113462 cites W2132026894 @default.
- W2166113462 cites W2132304324 @default.