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• W2166195924 abstract "Many pathogenic bacteria use cell-cell signaling to regulate the expression of factors contributing to virulence. Bacteria produce signals of diverse structural classes. The signal molecule known as diffusible signal factor (DSF) is a cis-unsaturated fatty acid that was first described in the plant pathogen Xanthomonas campestris. Recent work has shown that structurally related molecules produced by the unrelated bacteria Burkholderia cenocepacia and Pseudomonas aeruginosa regulate virulence, biofilm formation and antibiotic tolerance in these important human pathogens. Furthermore, DSF family signals have been shown to be involved in interspecies signaling that modulates bacterial behavior. An understanding of these diverse signaling mechanisms could suggest strategies for interference, with consequences for disease control." @default.
• W2166195924 created "2016-06-24" @default.
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• W2166195924 date "2011-03-01" @default.
• W2166195924 modified "2023-09-29" @default.
• W2166195924 title "Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria" @default.
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• W2166195924 doi "https://doi.org/10.1016/j.tim.2010.12.003" @default.
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