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• W2166404547 startingPage "49" @default.
• W2166404547 abstract "Arguably, the main challenge for contemporary genetics is to understand the function of every gene in a mammalian genome. The mouse has emerged as a model for this task because its genome can be manipulated in a number of ways to study gene function or mimic disease states. Two complementary genetic approaches can be used to generate mouse models. A reverse genetics or gene-driven approach (gene to phenotype) starts from a known gene and manipulates the genome to create genetically modified mice, such as knockouts. Alternatively, a forward genetics or phenotype-driven approach (phenotype to gene) involves screening mice for mutant phenotypes without previous knowledge of the genetic basis of the mutation. N-ethyl-N-nitrosourea (ENU) mutagenesis has been widely used for both approaches to generate mouse mutants. Here we review progress in ENU mutagenesis screening, with an emphasis on creating mouse models for human disorders." @default.
• W2166404547 created "2016-06-24" @default.
• W2166404547 creator A5040306687 @default.
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• W2166404547 date "2008-09-01" @default.
• W2166404547 modified "2023-10-10" @default.
• W2166404547 title "ENU Mutagenesis, a Way Forward to Understand Gene Function" @default.
• W2166404547 cites W1571263971 @default.
• W2166404547 cites W1679252210 @default.
• W2166404547 cites W1679992491 @default.
• W2166404547 cites W1925759916 @default.
• W2166404547 cites W1970740951 @default.
• W2166404547 cites W1971619863 @default.
• W2166404547 cites W1972819844 @default.
• W2166404547 cites W1974392743 @default.
• W2166404547 cites W1978920326 @default.
• W2166404547 cites W1981714996 @default.
• W2166404547 cites W1986338824 @default.
• W2166404547 cites W1988489353 @default.
• W2166404547 cites W1991090223 @default.
• W2166404547 cites W1992153476 @default.
• W2166404547 cites W1992494470 @default.
• W2166404547 cites W1993064034 @default.
• W2166404547 cites W1995008214 @default.
• W2166404547 cites W1997863210 @default.
• W2166404547 cites W2001888854 @default.
• W2166404547 cites W2001921094 @default.
• W2166404547 cites W2002005510 @default.
• W2166404547 cites W2002147490 @default.
• W2166404547 cites W2007444190 @default.
• W2166404547 cites W2013011285 @default.
• W2166404547 cites W2013666305 @default.
• W2166404547 cites W2014077667 @default.
• W2166404547 cites W2017624684 @default.
• W2166404547 cites W2020617528 @default.
• W2166404547 cites W2021451198 @default.
• W2166404547 cites W2022341605 @default.
• W2166404547 cites W2025143098 @default.
• W2166404547 cites W2026828087 @default.
• W2166404547 cites W2030775870 @default.
• W2166404547 cites W2031622194 @default.
• W2166404547 cites W2033316201 @default.
• W2166404547 cites W2034808739 @default.
• W2166404547 cites W2035123083 @default.
• W2166404547 cites W2036895432 @default.
• W2166404547 cites W2036897032 @default.
• W2166404547 cites W2037203426 @default.
• W2166404547 cites W2040597914 @default.
• W2166404547 cites W2040628766 @default.
• W2166404547 cites W2040801939 @default.
• W2166404547 cites W2041624821 @default.
• W2166404547 cites W2043384664 @default.
• W2166404547 cites W2046139844 @default.
• W2166404547 cites W2046518349 @default.
• W2166404547 cites W2046579578 @default.
• W2166404547 cites W2049556080 @default.
• W2166404547 cites W2049795287 @default.
• W2166404547 cites W2050812658 @default.
• W2166404547 cites W2052659593 @default.
• W2166404547 cites W2053876086 @default.
• W2166404547 cites W2054513544 @default.
• W2166404547 cites W2057208800 @default.
• W2166404547 cites W2061561206 @default.
• W2166404547 cites W2064185606 @default.
• W2166404547 cites W2065975305 @default.
• W2166404547 cites W2069927604 @default.
• W2166404547 cites W2070558630 @default.
• W2166404547 cites W2071002080 @default.
• W2166404547 cites W2074984352 @default.
• W2166404547 cites W2078606159 @default.
• W2166404547 cites W2082183576 @default.
• W2166404547 cites W2082229119 @default.
• W2166404547 cites W2085269742 @default.
• W2166404547 cites W2086508545 @default.
• W2166404547 cites W2086588218 @default.
• W2166404547 cites W2087022717 @default.
• W2166404547 cites W2088609959 @default.
• W2166404547 cites W2089680964 @default.
• W2166404547 cites W2097660065 @default.
• W2166404547 cites W2102037126 @default.
• W2166404547 cites W2104427970 @default.
• W2166404547 cites W2104867418 @default.
• W2166404547 cites W2106831300 @default.
• W2166404547 cites W2110029962 @default.
• W2166404547 cites W2110835181 @default.
• W2166404547 cites W2113281335 @default.
• W2166404547 cites W2113320287 @default.
• W2166404547 cites W2114570499 @default.
• W2166404547 cites W2119856466 @default.
• W2166404547 cites W2121157101 @default.
• W2166404547 cites W2121294464 @default.
• W2166404547 cites W2121467659 @default.
• W2166404547 cites W2122031852 @default.
• W2166404547 cites W2124070731 @default.

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