FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166413767> ?p ?o ?g. }

• W2166413767 endingPage "838" @default.
• W2166413767 startingPage "829" @default.
• W2166413767 abstract "Cardiovascular diseases, such as atherosclerosis and aneurysm, are closely associated with haemodynamic factors that are governed by luminal geometry. The present work aimed to study the effect of geometrical variation of aging aortas on haemodynamics. Six aged subjects with intricate geometrical features, such as bulging or twisted supra-aortic arteries, sharply curved arch and double-curved descending aorta, were chosen from our medical database. These six geometrically variant aortas were reconstructed and the pulsatile nature of the blood flow of these subject-specific aorta models investigated using computational fluid dynamics simulations. Realistic time-dependent boundary conditions are prescribed for various arteries of the aorta models. This study suggests that haemodynamics in the human aorta is highly dependent on geometrical features. The positioning and contouring of the supra-aortic arteries may be associated with the skewness of velocity profiles. The flow profiles in the aortic arch or bends are generally skewed towards the inner curvature wall and this skewness may give rise to the formation of secondary flow in the inner curvature wall of the distal arch. The degree of vorticity in the distal aortic arch is found to be related to the arch curvature. The helical nature of aortic haemodynamics is predominant in the systole phrase when it begins with a left-handed rotation and then vanishes in the ascending aorta, whereas a right-handed rotation persists in the distal aortic arch. Lower wall shear stress is also found in the ascending regions where secondary flow is present. The aorta with an irregular contour and large degree of curvature at its arch favours the development of the intra-aortic secondary flow that subsequently relates to the pathogenesis of atheroma. The present study identifies the general trend of haemodynamic behaviours associated with various local geometrical features. Combining the knowledge of the correlation between haemodynamics and the underlying risks in the development of cardiovascular diseases, our study hopes to provide a better understanding of the relationship between aortic morphology and developing pathobiology of cardiovascular diseases. As such, early medical planning as well as surgical interventions can be designed to retard or prevent the development of cardiovascular diseases." @default.
• W2166413767 created "2016-06-24" @default.
• W2166413767 creator A5049764220 @default.
• W2166413767 creator A5052879644 @default.
• W2166413767 creator A5054902727 @default.
• W2166413767 creator A5065035151 @default.
• W2166413767 creator A5070649123 @default.
• W2166413767 creator A5073964791 @default.
• W2166413767 date "2012-07-05" @default.
• W2166413767 modified "2023-10-06" @default.
• W2166413767 title "A computational fluid dynamics study on geometrical influence of the aorta on haemodynamics" @default.
• W2166413767 cites W178171836 @default.
• W2166413767 cites W1963543114 @default.
• W2166413767 cites W1965716876 @default.
• W2166413767 cites W1993517752 @default.
• W2166413767 cites W2014497476 @default.
• W2166413767 cites W2023309506 @default.
• W2166413767 cites W2024192061 @default.
• W2166413767 cites W2028789435 @default.
• W2166413767 cites W2033518278 @default.
• W2166413767 cites W2034449253 @default.
• W2166413767 cites W2040519846 @default.
• W2166413767 cites W2068639580 @default.
• W2166413767 cites W2077500167 @default.
• W2166413767 cites W2081100920 @default.
• W2166413767 cites W2086690123 @default.
• W2166413767 cites W2087473668 @default.
• W2166413767 cites W2094878091 @default.
• W2166413767 cites W2097663931 @default.
• W2166413767 cites W2114904626 @default.
• W2166413767 cites W2117766824 @default.
• W2166413767 cites W2129754481 @default.
• W2166413767 cites W2130701170 @default.
• W2166413767 cites W2137502064 @default.
• W2166413767 cites W4239713289 @default.
• W2166413767 doi "https://doi.org/10.1093/ejcts/ezs388" @default.
• W2166413767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22766960" @default.
• W2166413767 hasPublicationYear "2012" @default.
• W2166413767 type Work @default.
• W2166413767 sameAs 2166413767 @default.
• W2166413767 citedByCount "42" @default.
• W2166413767 countsByYear W21664137672012 @default.
• W2166413767 countsByYear W21664137672013 @default.
• W2166413767 countsByYear W21664137672014 @default.
• W2166413767 countsByYear W21664137672016 @default.
• W2166413767 countsByYear W21664137672017 @default.
• W2166413767 countsByYear W21664137672018 @default.
• W2166413767 countsByYear W21664137672019 @default.
• W2166413767 countsByYear W21664137672020 @default.
• W2166413767 countsByYear W21664137672021 @default.
• W2166413767 countsByYear W21664137672022 @default.
• W2166413767 countsByYear W21664137672023 @default.
• W2166413767 crossrefType "journal-article" @default.
• W2166413767 hasAuthorship W2166413767A5049764220 @default.
• W2166413767 hasAuthorship W2166413767A5052879644 @default.
• W2166413767 hasAuthorship W2166413767A5054902727 @default.
• W2166413767 hasAuthorship W2166413767A5065035151 @default.
• W2166413767 hasAuthorship W2166413767A5070649123 @default.
• W2166413767 hasAuthorship W2166413767A5073964791 @default.
• W2166413767 hasBestOaLocation W21664137671 @default.
• W2166413767 hasConcept C105702510 @default.
• W2166413767 hasConcept C121332964 @default.
• W2166413767 hasConcept C126322002 @default.
• W2166413767 hasConcept C127313418 @default.
• W2166413767 hasConcept C164705383 @default.
• W2166413767 hasConcept C178853913 @default.
• W2166413767 hasConcept C196558001 @default.
• W2166413767 hasConcept C21141959 @default.
• W2166413767 hasConcept C2524010 @default.
• W2166413767 hasConcept C2778249958 @default.
• W2166413767 hasConcept C2778384633 @default.
• W2166413767 hasConcept C2779980429 @default.
• W2166413767 hasConcept C2780663194 @default.
• W2166413767 hasConcept C2781285907 @default.
• W2166413767 hasConcept C33923547 @default.
• W2166413767 hasConcept C57879066 @default.
• W2166413767 hasConcept C71924100 @default.
• W2166413767 hasConcept C79191276 @default.
• W2166413767 hasConceptScore W2166413767C105702510 @default.
• W2166413767 hasConceptScore W2166413767C121332964 @default.
• W2166413767 hasConceptScore W2166413767C126322002 @default.
• W2166413767 hasConceptScore W2166413767C127313418 @default.
• W2166413767 hasConceptScore W2166413767C164705383 @default.
• W2166413767 hasConceptScore W2166413767C178853913 @default.
• W2166413767 hasConceptScore W2166413767C196558001 @default.
• W2166413767 hasConceptScore W2166413767C21141959 @default.
• W2166413767 hasConceptScore W2166413767C2524010 @default.
• W2166413767 hasConceptScore W2166413767C2778249958 @default.
• W2166413767 hasConceptScore W2166413767C2778384633 @default.
• W2166413767 hasConceptScore W2166413767C2779980429 @default.
• W2166413767 hasConceptScore W2166413767C2780663194 @default.
• W2166413767 hasConceptScore W2166413767C2781285907 @default.
• W2166413767 hasConceptScore W2166413767C33923547 @default.
• W2166413767 hasConceptScore W2166413767C57879066 @default.
• W2166413767 hasConceptScore W2166413767C71924100 @default.
• W2166413767 hasConceptScore W2166413767C79191276 @default.
• W2166413767 hasIssue "4" @default.
• W2166413767 hasLocation W21664137671 @default.

• next