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- W2166419904 abstract "AimsObesity is commonly associated with hypertension. Increased sympathetic tonus in obese subjects contributes to the underlying mechanism. However, the precise mechanisms whereby obesity induces this sympathetic activation remain unclear. Hepatic peroxisome proliferator-activated receptor (PPAR)-γ2 expression, which is reportedly upregulated during obesity development, affects sympathetic activation via hepatic vagal afferents. Herein, we report involvement of this neuronal relay in obesity-related hypertension." @default.
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- W2166419904 date "2011-08-08" @default.
- W2166419904 modified "2023-10-03" @default.
- W2166419904 title "Hepatic peroxisome proliferator-activated receptor-γ–fat-specific protein 27 pathway contributes to obesity-related hypertension via afferent vagal signals" @default.
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- W2166419904 doi "https://doi.org/10.1093/eurheartj/ehr265" @default.
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