FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166502023> ?p ?o ?g. }

• W2166502023 endingPage "232" @default.
• W2166502023 startingPage "226" @default.
• W2166502023 abstract "Microbial production of fatty acid derived chemicals and fuels is currently of great interest due to the limited resources and increasing prices of petroleum and petroleum-based products. The development of Saccharomyces cerevisiae as a fatty acid ethyl ester (FAEE) cell factory would represent an opportunity for biodiesel production due to its successful history in the biotechnology area. However, fatty acid (FA) biosynthesis is highly regulated and usually not high enough for developing an efficient production process. In S. cerevisiae, FAs are degraded by β-oxidation and a large fraction is utilized to synthesize steryl esters (SEs) and triacylglycerols (TAGs), which are not essential for the cell. Here, by eliminating non-essential FA utilization pathways, we developed a metabolic engineering strategy resulting in a S. cerevisiae strain that can overproduce FAs and in turn use these for producing FAEEs (biodiesel). Compared to the wild-type, there is an about 3-fold increase in free FA content in a strain devoid of both TAG and SE formation, a 4-fold increase in free FA content in a strain that is incapable of β-oxidation, and a 5-fold increase of free FAs in a strain lacking all of these non-essential FA utilization pathways. It is also demonstrated that there are similar positive effects on FAEE production in these deletion strains. The highest production of FAEEs is 17.2 mg/l in the strain in which all these pathways were blocked. The results of this study serve as a basis for further strategies to improve the production of FA derivatives in S. cerevisiae." @default.
• W2166502023 created "2016-06-24" @default.
• W2166502023 creator A5030672418 @default.
• W2166502023 creator A5043239620 @default.
• W2166502023 creator A5044241430 @default.
• W2166502023 creator A5063441710 @default.
• W2166502023 date "2014-02-01" @default.
• W2166502023 modified "2023-09-27" @default.
• W2166502023 title "Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid ethyl esters, an advanced biofuel, by eliminating non-essential fatty acid utilization pathways" @default.
• W2166502023 cites W1850569493 @default.
• W2166502023 cites W1913334531 @default.
• W2166502023 cites W1963951216 @default.
• W2166502023 cites W1969737313 @default.
• W2166502023 cites W1976247849 @default.
• W2166502023 cites W1986770169 @default.
• W2166502023 cites W2000538792 @default.
• W2166502023 cites W2010436846 @default.
• W2166502023 cites W2024038979 @default.
• W2166502023 cites W2025598646 @default.
• W2166502023 cites W2030719468 @default.
• W2166502023 cites W2033743665 @default.
• W2166502023 cites W2038591876 @default.
• W2166502023 cites W2039563917 @default.
• W2166502023 cites W2043237666 @default.
• W2166502023 cites W2045054941 @default.
• W2166502023 cites W2065967474 @default.
• W2166502023 cites W2069191162 @default.
• W2166502023 cites W2073265884 @default.
• W2166502023 cites W2074893062 @default.
• W2166502023 cites W2077705948 @default.
• W2166502023 cites W2094700891 @default.
• W2166502023 cites W2094758309 @default.
• W2166502023 cites W2099395427 @default.
• W2166502023 cites W2102470371 @default.
• W2166502023 cites W2102865022 @default.
• W2166502023 cites W2122375874 @default.
• W2166502023 cites W2128715992 @default.
• W2166502023 cites W2130625600 @default.
• W2166502023 cites W2140170815 @default.
• W2166502023 cites W2142079844 @default.
• W2166502023 cites W2160675272 @default.
• W2166502023 cites W2164098890 @default.
• W2166502023 cites W2164449327 @default.
• W2166502023 cites W2167030992 @default.
• W2166502023 cites W4242576040 @default.
• W2166502023 doi "https://doi.org/10.1016/j.apenergy.2013.10.003" @default.
• W2166502023 hasPublicationYear "2014" @default.
• W2166502023 type Work @default.
• W2166502023 sameAs 2166502023 @default.
• W2166502023 citedByCount "97" @default.
• W2166502023 countsByYear W21665020232014 @default.
• W2166502023 countsByYear W21665020232015 @default.
• W2166502023 countsByYear W21665020232016 @default.
• W2166502023 countsByYear W21665020232017 @default.
• W2166502023 countsByYear W21665020232018 @default.
• W2166502023 countsByYear W21665020232019 @default.
• W2166502023 countsByYear W21665020232020 @default.
• W2166502023 countsByYear W21665020232021 @default.
• W2166502023 countsByYear W21665020232022 @default.
• W2166502023 countsByYear W21665020232023 @default.
• W2166502023 crossrefType "journal-article" @default.
• W2166502023 hasAuthorship W2166502023A5030672418 @default.
• W2166502023 hasAuthorship W2166502023A5043239620 @default.
• W2166502023 hasAuthorship W2166502023A5044241430 @default.
• W2166502023 hasAuthorship W2166502023A5063441710 @default.
• W2166502023 hasBestOaLocation W21665020231 @default.
• W2166502023 hasConcept C100544194 @default.
• W2166502023 hasConcept C150903083 @default.
• W2166502023 hasConcept C161790260 @default.
• W2166502023 hasConcept C181199279 @default.
• W2166502023 hasConcept C185592680 @default.
• W2166502023 hasConcept C192989942 @default.
• W2166502023 hasConcept C2777576037 @default.
• W2166502023 hasConcept C2779222958 @default.
• W2166502023 hasConcept C31903555 @default.
• W2166502023 hasConcept C52896960 @default.
• W2166502023 hasConcept C53991642 @default.
• W2166502023 hasConcept C543025807 @default.
• W2166502023 hasConcept C55493867 @default.
• W2166502023 hasConcept C62231903 @default.
• W2166502023 hasConcept C6350086 @default.
• W2166502023 hasConcept C66910140 @default.
• W2166502023 hasConcept C86803240 @default.
• W2166502023 hasConceptScore W2166502023C100544194 @default.
• W2166502023 hasConceptScore W2166502023C150903083 @default.
• W2166502023 hasConceptScore W2166502023C161790260 @default.
• W2166502023 hasConceptScore W2166502023C181199279 @default.
• W2166502023 hasConceptScore W2166502023C185592680 @default.
• W2166502023 hasConceptScore W2166502023C192989942 @default.
• W2166502023 hasConceptScore W2166502023C2777576037 @default.
• W2166502023 hasConceptScore W2166502023C2779222958 @default.
• W2166502023 hasConceptScore W2166502023C31903555 @default.
• W2166502023 hasConceptScore W2166502023C52896960 @default.
• W2166502023 hasConceptScore W2166502023C53991642 @default.
• W2166502023 hasConceptScore W2166502023C543025807 @default.
• W2166502023 hasConceptScore W2166502023C55493867 @default.
• W2166502023 hasConceptScore W2166502023C62231903 @default.
• W2166502023 hasConceptScore W2166502023C6350086 @default.

• next