FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166508575> ?p ?o ?g. }

• W2166508575 endingPage "543" @default.
• W2166508575 startingPage "533" @default.
• W2166508575 abstract "Background Canine chronic enteropathies ( CE ) are believed to be caused by an aberrant immune response towards the intestinal microbiome. Administration of probiotics can alleviate colitis in people. In vitro effects of the probiotic Enterococcus faecium NCIMB 10415 E1707 ( EF ) previously have been evaluated using canine cells (e.g., whole blood, intestinal biopsies), but data on in vivo efficacy are lacking. Hypothesis/Objectives Administration of EF to dogs with food‐responsive CE will improve clinical outcome and decrease the intestinal inflammatory profile. Animals Dogs diagnosed with CE were prospectively recruited to receive a hydrolyzed elimination diet plus either a synbiotic product containing EF or placebo for 6 weeks. Both veterinary staff and owners were blinded to the treatment. Methods Clinical severity index ( CCECAI ), clinicopathological data and gene expression using intestinal biopsies ( TLR 2/4/5/9, IL ‐17A, IL ‐22, IL ‐23p19, RORC , IL ‐2, IL ‐12p35, TNF α, IL ‐4, IFN y, IL ‐10, TGF β, IL ‐1β, IL ‐18, NLRP 3, casp‐1, TFF 1, TFF 3 and PPAR y) before and after 6 weeks of treatment were analyzed using linear mixed modeling. Results Of the 45 cases recruited, 12 finished the clinical trial. Seven received the synbiotic and 5 the placebo product. There was no difference between groups or treatments regarding clinical efficacy, histology scores or expression of any of the investigated genes. Conclusions and clinical importance Standard dietary treatment induced rapid clinical response in all cases. Because the study was underpowered, it was not possible to determine whether or not EF had an additional effect within the time period of 6 weeks." @default.
• W2166508575 created "2016-06-24" @default.
• W2166508575 creator A5002726600 @default.
• W2166508575 creator A5036883027 @default.
• W2166508575 creator A5057338163 @default.
• W2166508575 creator A5061861242 @default.
• W2166508575 creator A5062945808 @default.
• W2166508575 creator A5070633627 @default.
• W2166508575 creator A5076556348 @default.
• W2166508575 date "2015-03-01" @default.
• W2166508575 modified "2023-10-15" @default.
• W2166508575 title "A Prospective, Randomized, Blinded, Placebo‐Controlled Pilot Study on the Effect of <i>Enterococcus faecium</i> on Clinical Activity and Intestinal Gene Expression in Canine Food‐Responsive Chronic Enteropathy" @default.
• W2166508575 cites W1499500424 @default.
• W2166508575 cites W1577577364 @default.
• W2166508575 cites W1592771441 @default.
• W2166508575 cites W1598654018 @default.
• W2166508575 cites W1828901639 @default.
• W2166508575 cites W1931031802 @default.
• W2166508575 cites W1984279003 @default.
• W2166508575 cites W1984502565 @default.
• W2166508575 cites W1987489268 @default.
• W2166508575 cites W1992325707 @default.
• W2166508575 cites W2003832985 @default.
• W2166508575 cites W2003939487 @default.
• W2166508575 cites W200570263 @default.
• W2166508575 cites W2008639259 @default.
• W2166508575 cites W2017761896 @default.
• W2166508575 cites W2019271374 @default.
• W2166508575 cites W2025889810 @default.
• W2166508575 cites W2026088200 @default.
• W2166508575 cites W2032388308 @default.
• W2166508575 cites W2045384054 @default.
• W2166508575 cites W2048088272 @default.
• W2166508575 cites W2052537077 @default.
• W2166508575 cites W2055959752 @default.
• W2166508575 cites W2057537288 @default.
• W2166508575 cites W2060839471 @default.
• W2166508575 cites W2065843773 @default.
• W2166508575 cites W2067305821 @default.
• W2166508575 cites W2071799261 @default.
• W2166508575 cites W2071927798 @default.
• W2166508575 cites W2074280408 @default.
• W2166508575 cites W2075781087 @default.
• W2166508575 cites W2080602987 @default.
• W2166508575 cites W2083050654 @default.
• W2166508575 cites W2097811455 @default.
• W2166508575 cites W2105942939 @default.
• W2166508575 cites W2119336597 @default.
• W2166508575 cites W2132241088 @default.
• W2166508575 cites W2134643141 @default.
• W2166508575 cites W2141125135 @default.
• W2166508575 cites W2146068085 @default.
• W2166508575 cites W2146641326 @default.
• W2166508575 cites W2155945680 @default.
• W2166508575 cites W2172466148 @default.
• W2166508575 cites W2180023734 @default.
• W2166508575 cites W2782304888 @default.
• W2166508575 cites W4238416248 @default.
• W2166508575 cites W4239056084 @default.
• W2166508575 cites W4245277907 @default.
• W2166508575 doi "https://doi.org/10.1111/jvim.12563" @default.
• W2166508575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4895498" @default.
• W2166508575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25776251" @default.
• W2166508575 hasPublicationYear "2015" @default.
• W2166508575 type Work @default.
• W2166508575 sameAs 2166508575 @default.
• W2166508575 citedByCount "43" @default.
• W2166508575 countsByYear W21665085752016 @default.
• W2166508575 countsByYear W21665085752017 @default.
• W2166508575 countsByYear W21665085752018 @default.
• W2166508575 countsByYear W21665085752019 @default.
• W2166508575 countsByYear W21665085752020 @default.
• W2166508575 countsByYear W21665085752021 @default.
• W2166508575 countsByYear W21665085752022 @default.
• W2166508575 countsByYear W21665085752023 @default.
• W2166508575 crossrefType "journal-article" @default.
• W2166508575 hasAuthorship W2166508575A5002726600 @default.
• W2166508575 hasAuthorship W2166508575A5036883027 @default.
• W2166508575 hasAuthorship W2166508575A5057338163 @default.
• W2166508575 hasAuthorship W2166508575A5061861242 @default.
• W2166508575 hasAuthorship W2166508575A5062945808 @default.
• W2166508575 hasAuthorship W2166508575A5070633627 @default.
• W2166508575 hasAuthorship W2166508575A5076556348 @default.
• W2166508575 hasBestOaLocation W21665085752 @default.
• W2166508575 hasConcept C126322002 @default.
• W2166508575 hasConcept C142724271 @default.
• W2166508575 hasConcept C203014093 @default.
• W2166508575 hasConcept C204787440 @default.
• W2166508575 hasConcept C27081682 @default.
• W2166508575 hasConcept C2777677444 @default.
• W2166508575 hasConcept C2778426112 @default.
• W2166508575 hasConcept C2779134260 @default.
• W2166508575 hasConcept C2780255968 @default.
• W2166508575 hasConcept C501593827 @default.
• W2166508575 hasConcept C523546767 @default.
• W2166508575 hasConcept C535046627 @default.
• W2166508575 hasConcept C54355233 @default.
• W2166508575 hasConcept C71924100 @default.

• next