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- W2166801034 abstract "This study was designed to determine whether dextran, gelatin or hydroxyethyl starch-based colloidal resuscitation fluids (CRF) are inhibitory to T lymphocyte activation and mitogenesis in vitro. Isolated peripheral blood lymphocytes from normal donors were activated with mitogen (PHA) and cultured in up to 50% v:v CRF. Dual-label flow cytometry for CD69 and CD25 were used to assess early and full T cell activation responses, respectively, and thymidine incorporation was used to assess mitogenesis. T cell activation and mitogenic responses were not inhibited in the presence of CRF, implying that any systemic immunodepression associated with CRF infusion is not directly related to CRF-mediated impairment of T cell activation." @default.
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- W2166801034 date "1998-08-01" @default.
- W2166801034 modified "2023-09-28" @default.
- W2166801034 title "Effects of resuscitation fluids on T cell immune responses" @default.
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- W2166801034 doi "https://doi.org/10.1093/bja/81.2.242" @default.
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