FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166884834> ?p ?o ?g. }

• W2166884834 endingPage "240" @default.
• W2166884834 startingPage "234" @default.
• W2166884834 abstract "Living systems must adapt quickly and stably to uncertain environments. A common theme in cellular regulation is the presence of multiple feedback loops in the network. An example of such a feedback structure is regulation of tryptophan concentration in Escherichia coli . Here, three distinct feedback mechanisms, namely genetic regulation, mRNA attenuation and enzyme inhibition, regulate tryptophan synthesis. A pertinent question is whether such multiple feedback loops are “a case of regulatory overkill, or do these different feedback regulators have distinct functions?” [Freeman (2000) Nature 295, 313–319]. Another moot question is how robustness to uncertainties can be achieved structurally through biological interactions. Correlation between the feedback structure and robustness can be systematically studied by tools commonly employed in feedback theory. An analysis of feedback strategies in the tryptophan system in E. coli reveals that the network complexity arising due to the distributed feedback structure is responsible for the rapid and stable response observed even in the presence of system uncertainties." @default.
• W2166884834 created "2016-06-24" @default.
• W2166884834 creator A5018041437 @default.
• W2166884834 creator A5071910318 @default.
• W2166884834 creator A5073351086 @default.
• W2166884834 date "2004-03-23" @default.
• W2166884834 modified "2023-09-26" @default.
• W2166884834 title "Multiple feedback loops are key to a robust dynamic performance of tryptophan regulation in <i>Escherichia coli</i>" @default.
• W2166884834 cites W1648346008 @default.
• W2166884834 cites W1766286635 @default.
• W2166884834 cites W1965738187 @default.
• W2166884834 cites W1973021296 @default.
• W2166884834 cites W2041042514 @default.
• W2166884834 cites W2043791622 @default.
• W2166884834 cites W2072526818 @default.
• W2166884834 cites W2098199730 @default.
• W2166884834 cites W2111167674 @default.
• W2166884834 cites W2111184079 @default.
• W2166884834 cites W2112651905 @default.
• W2166884834 cites W2133254839 @default.
• W2166884834 cites W2134800568 @default.
• W2166884834 cites W2134923619 @default.
• W2166884834 cites W2135852310 @default.
• W2166884834 cites W2136340808 @default.
• W2166884834 cites W2159100436 @default.
• W2166884834 cites W2168846334 @default.
• W2166884834 doi "https://doi.org/10.1016/s0014-5793(04)00310-2" @default.
• W2166884834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15063755" @default.
• W2166884834 hasPublicationYear "2004" @default.
• W2166884834 type Work @default.
• W2166884834 sameAs 2166884834 @default.
• W2166884834 citedByCount "45" @default.
• W2166884834 countsByYear W21668848342012 @default.
• W2166884834 countsByYear W21668848342013 @default.
• W2166884834 countsByYear W21668848342015 @default.
• W2166884834 countsByYear W21668848342016 @default.
• W2166884834 countsByYear W21668848342019 @default.
• W2166884834 countsByYear W21668848342021 @default.
• W2166884834 crossrefType "journal-article" @default.
• W2166884834 hasAuthorship W2166884834A5018041437 @default.
• W2166884834 hasAuthorship W2166884834A5071910318 @default.
• W2166884834 hasAuthorship W2166884834A5073351086 @default.
• W2166884834 hasBestOaLocation W21668848341 @default.
• W2166884834 hasConcept C104317684 @default.
• W2166884834 hasConcept C119599485 @default.
• W2166884834 hasConcept C121332964 @default.
• W2166884834 hasConcept C127413603 @default.
• W2166884834 hasConcept C133731056 @default.
• W2166884834 hasConcept C145420912 @default.
• W2166884834 hasConcept C154945302 @default.
• W2166884834 hasConcept C165801399 @default.
• W2166884834 hasConcept C186060115 @default.
• W2166884834 hasConcept C2775924081 @default.
• W2166884834 hasConcept C2776706248 @default.
• W2166884834 hasConcept C3017962763 @default.
• W2166884834 hasConcept C3018651601 @default.
• W2166884834 hasConcept C33923547 @default.
• W2166884834 hasConcept C41008148 @default.
• W2166884834 hasConcept C47446073 @default.
• W2166884834 hasConcept C48207687 @default.
• W2166884834 hasConcept C515207424 @default.
• W2166884834 hasConcept C547475151 @default.
• W2166884834 hasConcept C55493867 @default.
• W2166884834 hasConcept C62520636 @default.
• W2166884834 hasConcept C63479239 @default.
• W2166884834 hasConcept C70721500 @default.
• W2166884834 hasConcept C86803240 @default.
• W2166884834 hasConcept C93586867 @default.
• W2166884834 hasConceptScore W2166884834C104317684 @default.
• W2166884834 hasConceptScore W2166884834C119599485 @default.
• W2166884834 hasConceptScore W2166884834C121332964 @default.
• W2166884834 hasConceptScore W2166884834C127413603 @default.
• W2166884834 hasConceptScore W2166884834C133731056 @default.
• W2166884834 hasConceptScore W2166884834C145420912 @default.
• W2166884834 hasConceptScore W2166884834C154945302 @default.
• W2166884834 hasConceptScore W2166884834C165801399 @default.
• W2166884834 hasConceptScore W2166884834C186060115 @default.
• W2166884834 hasConceptScore W2166884834C2775924081 @default.
• W2166884834 hasConceptScore W2166884834C2776706248 @default.
• W2166884834 hasConceptScore W2166884834C3017962763 @default.
• W2166884834 hasConceptScore W2166884834C3018651601 @default.
• W2166884834 hasConceptScore W2166884834C33923547 @default.
• W2166884834 hasConceptScore W2166884834C41008148 @default.
• W2166884834 hasConceptScore W2166884834C47446073 @default.
• W2166884834 hasConceptScore W2166884834C48207687 @default.
• W2166884834 hasConceptScore W2166884834C515207424 @default.
• W2166884834 hasConceptScore W2166884834C547475151 @default.
• W2166884834 hasConceptScore W2166884834C55493867 @default.
• W2166884834 hasConceptScore W2166884834C62520636 @default.
• W2166884834 hasConceptScore W2166884834C63479239 @default.
• W2166884834 hasConceptScore W2166884834C70721500 @default.
• W2166884834 hasConceptScore W2166884834C86803240 @default.
• W2166884834 hasConceptScore W2166884834C93586867 @default.
• W2166884834 hasIssue "1-3" @default.
• W2166884834 hasLocation W21668848341 @default.
• W2166884834 hasLocation W21668848342 @default.
• W2166884834 hasOpenAccess W2166884834 @default.
• W2166884834 hasPrimaryLocation W21668848341 @default.

• next