FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166912428> ?p ?o ?g. }

• W2166912428 endingPage "501" @default.
• W2166912428 startingPage "489" @default.
• W2166912428 abstract "Alcohol use disorders (AUD) and chronic cigarette smoking are common among individuals with human immunodeficiency virus infection (HIV). Concurrent AUD in HIV is related to greater abnormalities in brain morphology and neurocognition than either condition alone. However, the potential influence of chronic smoking on brain morphology and neurocognition in those concurrently afflicted with AUD and HIV has not been examined. The goal of this retrospective analysis was to determine if chronic smoking affected neurocognition and brain morphology in a subsample of HIV-positive non-treatment-seeking heavy drinking participants (HD+) from our earlier work. Regional volumetric and neurocognitive comparisons were made among age-equivalent smoking HD+(n=17), nonsmoking HD+ (n=27), and nonsmoking HIV-negative light drinking controls (n=27) obtained from our original larger sample. Comprehensive neuropsychological assessment evaluated multiple neurocognitive domains of functioning and for potential psychiatric comorbidities. Quantitative volumetric measures of neocortical gray matter (GM), white matter (WM), subcortical structures, and sulcal and ventricular cerebral spinal fluid (CSF) were derived from high-resolution magnetic resonance images. The main findings were (1) smoking HD+ performed significantly worse than nonsmoking HD+ on measures of auditory-verbal (AV) learning, AV memory, and cognitive efficiency; (2) relative to controls, smoking HD+ demonstrated significantly lower neocortical GM volumes in all lobes except the occipital lobe, while nonsmoking HD+ showed only lower frontal GM volume compared with controls; (3) in the HD+ group, regional brain volumes and neurocognition were not influenced by viremia, highly active antiretroviral treatment, or Center for Disease Control symptom status, and no interactions were apparent with these variables or smoking status. Overall, the findings suggested that the direct and/or indirect effects of chronic cigarette smoking created an additional burden on the integrity of brain neurobiology and neurocognition in this cohort of HIV-positive heavy drinkers." @default.
• W2166912428 created "2016-06-24" @default.
• W2166912428 creator A5016655815 @default.
• W2166912428 creator A5029437650 @default.
• W2166912428 creator A5030259393 @default.
• W2166912428 creator A5040649202 @default.
• W2166912428 creator A5043086041 @default.
• W2166912428 creator A5077461136 @default.
• W2166912428 date "2007-11-01" @default.
• W2166912428 modified "2023-10-12" @default.
• W2166912428 title "Chronic cigarette smoking and heavy drinking in human immunodeficiency virus: consequences for neurocognition and brain morphology" @default.
• W2166912428 cites W1553609571 @default.
• W2166912428 cites W1559813904 @default.
• W2166912428 cites W1845813830 @default.
• W2166912428 cites W1964643219 @default.
• W2166912428 cites W1966310359 @default.
• W2166912428 cites W1971909077 @default.
• W2166912428 cites W1972359508 @default.
• W2166912428 cites W1973124530 @default.
• W2166912428 cites W1975095592 @default.
• W2166912428 cites W1975131627 @default.
• W2166912428 cites W1977370225 @default.
• W2166912428 cites W1977664132 @default.
• W2166912428 cites W1979501373 @default.
• W2166912428 cites W1980050010 @default.
• W2166912428 cites W1981000616 @default.
• W2166912428 cites W1986903834 @default.
• W2166912428 cites W1988184696 @default.
• W2166912428 cites W1989012904 @default.
• W2166912428 cites W1991970102 @default.
• W2166912428 cites W1994573937 @default.
• W2166912428 cites W1998274173 @default.
• W2166912428 cites W1998926030 @default.
• W2166912428 cites W2000125680 @default.
• W2166912428 cites W2005601925 @default.
• W2166912428 cites W2009677158 @default.
• W2166912428 cites W2012689908 @default.
• W2166912428 cites W2012954908 @default.
• W2166912428 cites W2014695484 @default.
• W2166912428 cites W2015936728 @default.
• W2166912428 cites W2017026587 @default.
• W2166912428 cites W2017804398 @default.
• W2166912428 cites W2018236079 @default.
• W2166912428 cites W2020552465 @default.
• W2166912428 cites W2020750117 @default.
• W2166912428 cites W2021877868 @default.
• W2166912428 cites W2023794288 @default.
• W2166912428 cites W2028058169 @default.
• W2166912428 cites W2029296465 @default.
• W2166912428 cites W2033875947 @default.
• W2166912428 cites W2034754065 @default.
• W2166912428 cites W2034990918 @default.
• W2166912428 cites W2036495407 @default.
• W2166912428 cites W2037906085 @default.
• W2166912428 cites W2043341916 @default.
• W2166912428 cites W2047384740 @default.
• W2166912428 cites W2048397371 @default.
• W2166912428 cites W2049655114 @default.
• W2166912428 cites W2052110010 @default.
• W2166912428 cites W2053178989 @default.
• W2166912428 cites W2053813390 @default.
• W2166912428 cites W2056174699 @default.
• W2166912428 cites W2057674979 @default.
• W2166912428 cites W2058204968 @default.
• W2166912428 cites W2060349106 @default.
• W2166912428 cites W2065371230 @default.
• W2166912428 cites W2066103879 @default.
• W2166912428 cites W2075438570 @default.
• W2166912428 cites W2077947740 @default.
• W2166912428 cites W2079443737 @default.
• W2166912428 cites W2082313651 @default.
• W2166912428 cites W2084702457 @default.
• W2166912428 cites W2089374096 @default.
• W2166912428 cites W2108654808 @default.
• W2166912428 cites W2111446187 @default.
• W2166912428 cites W2111749009 @default.
• W2166912428 cites W2111750001 @default.
• W2166912428 cites W2117602475 @default.
• W2166912428 cites W2117792476 @default.
• W2166912428 cites W2120714534 @default.
• W2166912428 cites W2122612153 @default.
• W2166912428 cites W2123412014 @default.
• W2166912428 cites W2126045455 @default.
• W2166912428 cites W2127919739 @default.
• W2166912428 cites W2129962799 @default.
• W2166912428 cites W2134908531 @default.
• W2166912428 cites W2135022332 @default.
• W2166912428 cites W2135620412 @default.
• W2166912428 cites W2139789446 @default.
• W2166912428 cites W2139898307 @default.
• W2166912428 cites W2141249815 @default.
• W2166912428 cites W2141757584 @default.
• W2166912428 cites W2153858533 @default.
• W2166912428 cites W2158628116 @default.
• W2166912428 cites W2161160275 @default.
• W2166912428 cites W2161198266 @default.
• W2166912428 cites W2166367939 @default.
• W2166912428 cites W2169005238 @default.

• next