FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2166943941> ?p ?o ?g. }

• W2166943941 endingPage "1172" @default.
• W2166943941 startingPage "1162" @default.
• W2166943941 abstract "Patients with newly diagnosed, pulmonary tuberculosis had a tuberculin-specific defect in IL-2 production. Mean PPD-induced IL-2 activity was 81.2% lower in patients as compared with healthy tuberculin reactors. PPD-induced expression of T cell IL-2 receptors was 5.9 times less in peripheral blood mononuclear cells of patients with tuberculosis as compared with healthy tuberculin reactors. Furthermore, purified IL-2 failed to correct PPD-induced blastogenesis in patients. Suppression by adherent cells was operative in one group of patients; adherent cell depletion increased their T cell production of IL-2 7.2-fold. A second group of patients with low IL-2 production did not have suppressor adherent cells and were clinically distinct, with more extensive disease on chest x ray. The basis for low IL-2 production in such individuals is unknown. Disordered regulation of IL-2 metabolism may be a key feature in the depressed cellular immune response of tuberculosis." @default.
• W2166943941 created "2016-06-24" @default.
• W2166943941 creator A5084507037 @default.
• W2166943941 creator A5085776457 @default.
• W2166943941 creator A5091231171 @default.
• W2166943941 date "1986-05-01" @default.
• W2166943941 modified "2023-10-18" @default.
• W2166943941 title "Defective interleukin 2 production and responsiveness in human pulmonary tuberculosis." @default.
• W2166943941 cites W145871740 @default.
• W2166943941 cites W1506157243 @default.
• W2166943941 cites W1523459799 @default.
• W2166943941 cites W1605979477 @default.
• W2166943941 cites W1651047233 @default.
• W2166943941 cites W1902339425 @default.
• W2166943941 cites W1917376276 @default.
• W2166943941 cites W1965995080 @default.
• W2166943941 cites W1967475931 @default.
• W2166943941 cites W1971661892 @default.
• W2166943941 cites W1972602604 @default.
• W2166943941 cites W1973160057 @default.
• W2166943941 cites W1998716708 @default.
• W2166943941 cites W2005689945 @default.
• W2166943941 cites W2038056978 @default.
• W2166943941 cites W2038862088 @default.
• W2166943941 cites W2040878354 @default.
• W2166943941 cites W2048642240 @default.
• W2166943941 cites W2052783740 @default.
• W2166943941 cites W2061241669 @default.
• W2166943941 cites W2079371763 @default.
• W2166943941 cites W2088354306 @default.
• W2166943941 cites W2133305280 @default.
• W2166943941 cites W2155826396 @default.
• W2166943941 cites W2158128286 @default.
• W2166943941 cites W2236352479 @default.
• W2166943941 cites W2238468601 @default.
• W2166943941 cites W3111856753 @default.
• W2166943941 cites W4290462535 @default.
• W2166943941 cites W87082738 @default.
• W2166943941 doi "https://doi.org/10.1084/jem.163.5.1162" @default.
• W2166943941 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2188106" @default.
• W2166943941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2939169" @default.
• W2166943941 hasPublicationYear "1986" @default.
• W2166943941 type Work @default.
• W2166943941 sameAs 2166943941 @default.
• W2166943941 citedByCount "161" @default.
• W2166943941 countsByYear W21669439412012 @default.
• W2166943941 countsByYear W21669439412014 @default.
• W2166943941 countsByYear W21669439412015 @default.
• W2166943941 countsByYear W21669439412016 @default.
• W2166943941 countsByYear W21669439412017 @default.
• W2166943941 countsByYear W21669439412018 @default.
• W2166943941 countsByYear W21669439412019 @default.
• W2166943941 countsByYear W21669439412020 @default.
• W2166943941 countsByYear W21669439412021 @default.
• W2166943941 crossrefType "journal-article" @default.
• W2166943941 hasAuthorship W2166943941A5084507037 @default.
• W2166943941 hasAuthorship W2166943941A5085776457 @default.
• W2166943941 hasAuthorship W2166943941A5091231171 @default.
• W2166943941 hasBestOaLocation W21669439411 @default.
• W2166943941 hasConcept C137061746 @default.
• W2166943941 hasConcept C142724271 @default.
• W2166943941 hasConcept C202751555 @default.
• W2166943941 hasConcept C203014093 @default.
• W2166943941 hasConcept C2776090121 @default.
• W2166943941 hasConcept C2776247216 @default.
• W2166943941 hasConcept C2777371288 @default.
• W2166943941 hasConcept C2781069245 @default.
• W2166943941 hasConcept C55493867 @default.
• W2166943941 hasConcept C71924100 @default.
• W2166943941 hasConcept C86803240 @default.
• W2166943941 hasConcept C8891405 @default.
• W2166943941 hasConceptScore W2166943941C137061746 @default.
• W2166943941 hasConceptScore W2166943941C142724271 @default.
• W2166943941 hasConceptScore W2166943941C202751555 @default.
• W2166943941 hasConceptScore W2166943941C203014093 @default.
• W2166943941 hasConceptScore W2166943941C2776090121 @default.
• W2166943941 hasConceptScore W2166943941C2776247216 @default.
• W2166943941 hasConceptScore W2166943941C2777371288 @default.
• W2166943941 hasConceptScore W2166943941C2781069245 @default.
• W2166943941 hasConceptScore W2166943941C55493867 @default.
• W2166943941 hasConceptScore W2166943941C71924100 @default.
• W2166943941 hasConceptScore W2166943941C86803240 @default.
• W2166943941 hasConceptScore W2166943941C8891405 @default.
• W2166943941 hasIssue "5" @default.
• W2166943941 hasLocation W21669439411 @default.
• W2166943941 hasLocation W21669439412 @default.
• W2166943941 hasLocation W21669439413 @default.
• W2166943941 hasLocation W21669439414 @default.
• W2166943941 hasOpenAccess W2166943941 @default.
• W2166943941 hasPrimaryLocation W21669439411 @default.
• W2166943941 hasRelatedWork W2046864150 @default.
• W2166943941 hasRelatedWork W2051111573 @default.
• W2166943941 hasRelatedWork W2103863744 @default.
• W2166943941 hasRelatedWork W2119122291 @default.
• W2166943941 hasRelatedWork W2147495461 @default.
• W2166943941 hasRelatedWork W2392566498 @default.
• W2166943941 hasRelatedWork W2412611065 @default.
• W2166943941 hasRelatedWork W2763200999 @default.

• next