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- W2166959897 abstract "A sensitive and simple assay for the detection of Pb(2+) in aqueous solutions is reported. It takes advantage of the high affinity between single-stranded DNA (ssDNA) and single-walled carbon nanotubes (SWCNT) as well as the capability of SWCNT in fluorescence quenching. Lead(II) catalyzes the cleavage of a fluorescently labeled DNA substrate by a DNAzyme, which releases the single-stranded product to be adsorbed onto a SWCNT. The decrease in fluorescence is proportional to the Pb(2+) concentration. Concentrations as low as 1 nM Pb(2+) in water could be detected and the detection range spans over 5 orders of magnitude. The unique combination of Pb-specific DNAzyme with SWCNT produces a universal, facile and cost-effective sensing platform for lead ions. The concept can be applied to the design of detection assays for other metal ions or small molecules." @default.
- W2166959897 created "2016-06-24" @default.
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- W2166959897 date "2011-01-01" @default.
- W2166959897 modified "2023-09-27" @default.
- W2166959897 title "Combing DNAzyme with single-walled carbon nanotubes for detection of Pb(<scp>ii</scp>) in water" @default.
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- W2166959897 doi "https://doi.org/10.1039/c0an00709a" @default.
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