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- W2167028236 abstract "Hemidesmus indicus root in the form of suspension in water (10 mg/ml) containing 15.5 mM NaCl, 3 mM KCl and 12 mM glucose, when injected into the ligated jejunal sac (1 ml/sac) of rat, increased the absorption of water, Na+ and K+ (but not glucose) from the sac. This bioactivity was present in the water extract (5 or 10 mg/sac) of the root and not in the hexane extract. In contrast, the ethanol extract decreased the absorption of water and electrolytes from the jejunal sac. The effect of water extract was not affected by heat at 100 °C for 30 min. Intraperitoneal administration of the water extract (50 to 200 mg/kg) was devoid of any significant effect on the jejunal absorption. Neither the root suspension nor the water extract (125–500 mg/kg) showed any significant anti-ulcer and diuretic activities in rats. The intestinal motility was also not influenced by the root (water extract) when tested in mice. The present study indicates that H. indicus root powder or its water extract can be incorporated in oral rehydrating salt solution (ORS) for increasing its anti-diarrhoeal efficacy. Copyright © 2004 John Wiley & Sons, Ltd." @default.
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- W2167028236 date "2004-07-01" @default.
- W2167028236 modified "2023-09-23" @default.
- W2167028236 title "Enhancement in the absorption of water and electrolytes from rat intestine byHemidesmus indicus R. Br. root(water extract)" @default.
- W2167028236 doi "https://doi.org/10.1002/ptr.1402" @default.
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