FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167079388> ?p ?o ?g. }

• W2167079388 endingPage "636" @default.
• W2167079388 startingPage "628" @default.
• W2167079388 abstract "Purpose A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Materials and Methods Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose <6 to 7 Gy. OARs included brain, eyes, oral cavity, parotids, thyroid, lungs, heart, kidneys, liver, spleen, stomach, abdominal cavity, bladder, rectum, and genitals. Pretreatment quality assurance consisted of portal dosimetry comparisons, scoring the delivery to calculation agreement with the gamma agreement index. Results The median total body volume in the study was 57 liters (range, 49–81 liters), for an average diameter of 47 cm (range, 46–53 cm) and a total length ranging from 95 to 112 cm. The median PTV volume was 6.8 liters (range, 5.8–10.8 liters). The mean dose to PTV was 109% (range, 107–112%). The global mean of median dose to all OARs was 4.9 Gy (range, 4.5–5.1 Gy over the 5 patients). The individual mean of median doses per organ ranged from 2.3 Gy (oral cavity) to 7.3 Gy (bowels cavity). Preclinical quality assurance resulted in a mean gamma agreement index of 94.3 ± 5.1%. The delivery time measured from quality assurance runs was 13 minutes. Conclusion Sparing of normal tissues with adequate coverage of skeletal bones was shown to be feasible with RapidArc. Pretreatment quality assurance measurements confirmed the technical agreement between expected and actually delivered dose distributions, suggesting the possibility of incorporating this technique in the treatment options for patients. A preclinical investigation was undertaken to explore a treatment technique for total marrow irradiation using RapidArc, a volumetric modulated arc technique. Computed tomography datasets of 5 patients were included. Plans with eight overlapping coaxial arcs were optimized for 6-MV photon beams. Dose prescription was 12 Gy in 2 Gy per fraction, normalized so that 100% isodose covered 85% of the planning target volume (PTV). The PTV consisted of the whole skeleton (including ribs and sternum), from the top of the skull to the medium distal third of the femurs. Planning objectives for organs at risk (OARs) were constrained to a median dose <6 to 7 Gy. OARs included brain, eyes, oral cavity, parotids, thyroid, lungs, heart, kidneys, liver, spleen, stomach, abdominal cavity, bladder, rectum, and genitals. Pretreatment quality assurance consisted of portal dosimetry comparisons, scoring the delivery to calculation agreement with the gamma agreement index. The median total body volume in the study was 57 liters (range, 49–81 liters), for an average diameter of 47 cm (range, 46–53 cm) and a total length ranging from 95 to 112 cm. The median PTV volume was 6.8 liters (range, 5.8–10.8 liters). The mean dose to PTV was 109% (range, 107–112%). The global mean of median dose to all OARs was 4.9 Gy (range, 4.5–5.1 Gy over the 5 patients). The individual mean of median doses per organ ranged from 2.3 Gy (oral cavity) to 7.3 Gy (bowels cavity). Preclinical quality assurance resulted in a mean gamma agreement index of 94.3 ± 5.1%. The delivery time measured from quality assurance runs was 13 minutes. Sparing of normal tissues with adequate coverage of skeletal bones was shown to be feasible with RapidArc. Pretreatment quality assurance measurements confirmed the technical agreement between expected and actually delivered dose distributions, suggesting the possibility of incorporating this technique in the treatment options for patients." @default.
• W2167079388 created "2016-06-24" @default.
• W2167079388 creator A5016462782 @default.
• W2167079388 creator A5023261246 @default.
• W2167079388 creator A5034426119 @default.
• W2167079388 creator A5048685622 @default.
• W2167079388 creator A5071706202 @default.
• W2167079388 creator A5075534279 @default.
• W2167079388 creator A5082045927 @default.
• W2167079388 creator A5087468389 @default.
• W2167079388 creator A5088463386 @default.
• W2167079388 creator A5090857723 @default.
• W2167079388 date "2011-06-01" @default.
• W2167079388 modified "2023-09-26" @default.
• W2167079388 title "Preclinical Assessment of Volumetric Modulated Arc Therapy for Total Marrow Irradiation" @default.
• W2167079388 cites W1959073718 @default.
• W2167079388 cites W1967121735 @default.
• W2167079388 cites W1978978394 @default.
• W2167079388 cites W1984911952 @default.
• W2167079388 cites W1987544780 @default.
• W2167079388 cites W2021613090 @default.
• W2167079388 cites W2025188592 @default.
• W2167079388 cites W2035502715 @default.
• W2167079388 cites W2043009009 @default.
• W2167079388 cites W2046175574 @default.
• W2167079388 cites W2052149272 @default.
• W2167079388 cites W2063921899 @default.
• W2167079388 cites W2070406918 @default.
• W2167079388 cites W2071579945 @default.
• W2167079388 cites W2076623068 @default.
• W2167079388 cites W2084851290 @default.
• W2167079388 cites W2091603229 @default.
• W2167079388 cites W2104848762 @default.
• W2167079388 cites W2122657363 @default.
• W2167079388 cites W2134390003 @default.
• W2167079388 cites W2136506329 @default.
• W2167079388 cites W2141540810 @default.
• W2167079388 cites W2143200412 @default.
• W2167079388 cites W2326018134 @default.
• W2167079388 cites W66769540 @default.
• W2167079388 doi "https://doi.org/10.1016/j.ijrobp.2010.11.028" @default.
• W2167079388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21277109" @default.
• W2167079388 hasPublicationYear "2011" @default.
• W2167079388 type Work @default.
• W2167079388 sameAs 2167079388 @default.
• W2167079388 citedByCount "67" @default.
• W2167079388 countsByYear W21670793882012 @default.
• W2167079388 countsByYear W21670793882013 @default.
• W2167079388 countsByYear W21670793882014 @default.
• W2167079388 countsByYear W21670793882015 @default.
• W2167079388 countsByYear W21670793882016 @default.
• W2167079388 countsByYear W21670793882017 @default.
• W2167079388 countsByYear W21670793882018 @default.
• W2167079388 countsByYear W21670793882019 @default.
• W2167079388 countsByYear W21670793882020 @default.
• W2167079388 countsByYear W21670793882021 @default.
• W2167079388 countsByYear W21670793882022 @default.
• W2167079388 countsByYear W21670793882023 @default.
• W2167079388 crossrefType "journal-article" @default.
• W2167079388 hasAuthorship W2167079388A5016462782 @default.
• W2167079388 hasAuthorship W2167079388A5023261246 @default.
• W2167079388 hasAuthorship W2167079388A5034426119 @default.
• W2167079388 hasAuthorship W2167079388A5048685622 @default.
• W2167079388 hasAuthorship W2167079388A5071706202 @default.
• W2167079388 hasAuthorship W2167079388A5075534279 @default.
• W2167079388 hasAuthorship W2167079388A5082045927 @default.
• W2167079388 hasAuthorship W2167079388A5087468389 @default.
• W2167079388 hasAuthorship W2167079388A5088463386 @default.
• W2167079388 hasAuthorship W2167079388A5090857723 @default.
• W2167079388 hasConcept C126838900 @default.
• W2167079388 hasConcept C201645570 @default.
• W2167079388 hasConcept C2989005 @default.
• W2167079388 hasConcept C509974204 @default.
• W2167079388 hasConcept C71924100 @default.
• W2167079388 hasConcept C75088862 @default.
• W2167079388 hasConceptScore W2167079388C126838900 @default.
• W2167079388 hasConceptScore W2167079388C201645570 @default.
• W2167079388 hasConceptScore W2167079388C2989005 @default.
• W2167079388 hasConceptScore W2167079388C509974204 @default.
• W2167079388 hasConceptScore W2167079388C71924100 @default.
• W2167079388 hasConceptScore W2167079388C75088862 @default.
• W2167079388 hasIssue "2" @default.
• W2167079388 hasLocation W21670793881 @default.
• W2167079388 hasLocation W21670793882 @default.
• W2167079388 hasOpenAccess W2167079388 @default.
• W2167079388 hasPrimaryLocation W21670793881 @default.
• W2167079388 hasRelatedWork W1650996660 @default.
• W2167079388 hasRelatedWork W2050101289 @default.
• W2167079388 hasRelatedWork W2117141716 @default.
• W2167079388 hasRelatedWork W2144622085 @default.
• W2167079388 hasRelatedWork W2186742268 @default.
• W2167079388 hasRelatedWork W2487329160 @default.
• W2167079388 hasRelatedWork W2529481322 @default.
• W2167079388 hasRelatedWork W3029539430 @default.
• W2167079388 hasRelatedWork W3030063216 @default.
• W2167079388 hasRelatedWork W3146372209 @default.
• W2167079388 hasVolume "80" @default.
• W2167079388 isParatext "false" @default.

• next