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• W2167155713 abstract "Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network parts lists, network topology models, network control logic models, and dynamic models. Here we will describe some examples for each of these categories. We will study the topology of gene regulatory networks in yeast in more detail, comparing a direct network derived from transcription factor binding data and an indirect network derived from genome-wide expression data in mutants. Regarding the network dynamics we briefly describe discrete and continuous approaches to network modelling, then describe a hybrid model called Finite State Linear Model and demonstrate that some simple network dynamics can be simulated in this model." @default.
• W2167155713 created "2016-06-24" @default.
• W2167155713 creator A5019704028 @default.
• W2167155713 creator A5081419327 @default.
• W2167155713 date "2007-09-01" @default.
• W2167155713 modified "2023-10-11" @default.
• W2167155713 title "Current approaches to gene regulatory network modelling" @default.
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