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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167191188> ?p ?o ?g. }

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• W2167191188 abstract "Psoriasis is a common immune-mediated skin disease producing significant morbidity. Tumour necrosis factor (TNF)-alpha, a pro-inflammatory cytokine, plays a key role in the cutaneous inflammation characteristic of psoriasis. Infliximab is a chimeric monoclonal antibody that specifically binds to TNF-alpha, thereby blocking its biological activity. Data from Phase II and III studies indicate that infliximab is a highly effective, rapidly acting systemic therapy for patients with moderate-to-severe psoriasis. Regular 8-weekly infusions of infliximab maintain significant clinical improvement in the majority of patients for at least 1 year. Infliximab is generally well tolerated, but patients may be susceptible to infection and malignancy." @default.
• W2167191188 created "2016-06-24" @default.
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• W2167191188 date "2006-07-20" @default.
• W2167191188 modified "2023-10-04" @default.
• W2167191188 title "Infliximab for the treatment of psoriasis" @default.
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• W2167191188 doi "https://doi.org/10.1517/14712598.6.8.797" @default.
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