FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167234733> ?p ?o ?g. }

• W2167234733 endingPage "700" @default.
• W2167234733 startingPage "693" @default.
• W2167234733 abstract "The existence of a furosemide-sensitive Cl- transport pathway activated by external Ca2+ and Mg2+ has been demonstrated previously in studies of Cl- influx across the lamprey erythrocyte membrane. The aim of the present study was to characterize further specific Cl- transport pathways, especially those involved in Cl- efflux, in the red blood cell membrane of Lampetra fluviatilis. Cl- efflux was inhibited by 0.05 mmol l-1 dihydroindenyloxyalkanoic acid (DIOA) (81%), 1 mmol l-1 furosemide (76%) and 0.1 mmol l-1 niflumic acid (54%). Bumetanide (100 mumol l-1) and DIDS (100 mumol l-1) had no effect effect on Cl- efflux. Substitution of external Cl- by gluconate, but not by NO3-, led to a gradual decline of Cl- efflux. In addition, the removal of external Ca2+ resulted in a significant reduction in the rate of Cl- efflux. Membrane depolarization caused by increasing external K+ concentration or by inhibiting K+ channels with 1 mmol l-1 Ba2+ did not affect Cl- efflux. The furosemide-sensitive component of Cl- influx was a saturable function of external [Cl-] with an apparent K(m) of approximately 92 mmol l-1 and Vmax of approximately 17.8 mmol l-1 cells-1 h-1. Furosemide did not affect intracellular Cl- concentration (57.6 +/- 5.2 mmol l-1 cell water), measured using an ion-selective Cl- electrode, showing that a furosemide-sensitive pathway is not involved in net Cl- movement. A gradual fall (from 28.1 +/- 1.4 to 15.0 +/- 1.3 mmol l-1 cells-1 h-1) in unidirectional Cl- influx with time was observed within 3 h of cell preincubation in the standard physiological medium. These data provide evidence for the existence for an electroneutral furosemide-sensitive anion-exchange pathway in the lamprey erythrocyte membrane that accepts chloride and nitrate, but not bicarbonate or bromide." @default.
• W2167234733 created "2016-06-24" @default.
• W2167234733 creator A5001290290 @default.
• W2167234733 creator A5028256511 @default.
• W2167234733 creator A5079523888 @default.
• W2167234733 date "1998-03-01" @default.
• W2167234733 modified "2023-09-23" @default.
• W2167234733 title "Chloride transport in red blood cells of lamprey Lampetra fluviatilis: evidence for a novel anion-exchange system." @default.
• W2167234733 cites W112121826 @default.
• W2167234733 cites W1562628830 @default.
• W2167234733 cites W169027918 @default.
• W2167234733 cites W1770178370 @default.
• W2167234733 cites W1964313628 @default.
• W2167234733 cites W1983354901 @default.
• W2167234733 cites W2003002844 @default.
• W2167234733 cites W2003979170 @default.
• W2167234733 cites W2005728445 @default.
• W2167234733 cites W2006291859 @default.
• W2167234733 cites W2036212834 @default.
• W2167234733 cites W2038975562 @default.
• W2167234733 cites W2048833017 @default.
• W2167234733 cites W2082423616 @default.
• W2167234733 cites W2093463052 @default.
• W2167234733 cites W2121342734 @default.
• W2167234733 cites W2126501063 @default.
• W2167234733 cites W2167967321 @default.
• W2167234733 cites W2188891757 @default.
• W2167234733 cites W2206949507 @default.
• W2167234733 cites W2240406224 @default.
• W2167234733 cites W2242135922 @default.
• W2167234733 cites W2258613131 @default.
• W2167234733 cites W2273565642 @default.
• W2167234733 cites W2340166902 @default.
• W2167234733 cites W2397249589 @default.
• W2167234733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9542152" @default.
• W2167234733 hasPublicationYear "1998" @default.
• W2167234733 type Work @default.
• W2167234733 sameAs 2167234733 @default.
• W2167234733 citedByCount "3" @default.
• W2167234733 countsByYear W21672347332022 @default.
• W2167234733 crossrefType "journal-article" @default.
• W2167234733 hasAuthorship W2167234733A5001290290 @default.
• W2167234733 hasAuthorship W2167234733A5028256511 @default.
• W2167234733 hasAuthorship W2167234733A5079523888 @default.
• W2167234733 hasConcept C124815738 @default.
• W2167234733 hasConcept C12554922 @default.
• W2167234733 hasConcept C178790620 @default.
• W2167234733 hasConcept C181911157 @default.
• W2167234733 hasConcept C185592680 @default.
• W2167234733 hasConcept C200082930 @default.
• W2167234733 hasConcept C2776557347 @default.
• W2167234733 hasConcept C2777955127 @default.
• W2167234733 hasConcept C2778212192 @default.
• W2167234733 hasConcept C2779533339 @default.
• W2167234733 hasConcept C2779700409 @default.
• W2167234733 hasConcept C2780417240 @default.
• W2167234733 hasConcept C41625074 @default.
• W2167234733 hasConcept C505870484 @default.
• W2167234733 hasConcept C55493867 @default.
• W2167234733 hasConcept C57181701 @default.
• W2167234733 hasConcept C57947595 @default.
• W2167234733 hasConcept C86803240 @default.
• W2167234733 hasConcept C99975950 @default.
• W2167234733 hasConceptScore W2167234733C124815738 @default.
• W2167234733 hasConceptScore W2167234733C12554922 @default.
• W2167234733 hasConceptScore W2167234733C178790620 @default.
• W2167234733 hasConceptScore W2167234733C181911157 @default.
• W2167234733 hasConceptScore W2167234733C185592680 @default.
• W2167234733 hasConceptScore W2167234733C200082930 @default.
• W2167234733 hasConceptScore W2167234733C2776557347 @default.
• W2167234733 hasConceptScore W2167234733C2777955127 @default.
• W2167234733 hasConceptScore W2167234733C2778212192 @default.
• W2167234733 hasConceptScore W2167234733C2779533339 @default.
• W2167234733 hasConceptScore W2167234733C2779700409 @default.
• W2167234733 hasConceptScore W2167234733C2780417240 @default.
• W2167234733 hasConceptScore W2167234733C41625074 @default.
• W2167234733 hasConceptScore W2167234733C505870484 @default.
• W2167234733 hasConceptScore W2167234733C55493867 @default.
• W2167234733 hasConceptScore W2167234733C57181701 @default.
• W2167234733 hasConceptScore W2167234733C57947595 @default.
• W2167234733 hasConceptScore W2167234733C86803240 @default.
• W2167234733 hasConceptScore W2167234733C99975950 @default.
• W2167234733 hasIssue "Pt 5" @default.
• W2167234733 hasLocation W21672347331 @default.
• W2167234733 hasOpenAccess W2167234733 @default.
• W2167234733 hasPrimaryLocation W21672347331 @default.
• W2167234733 hasRelatedWork W1575163018 @default.
• W2167234733 hasRelatedWork W1790661926 @default.
• W2167234733 hasRelatedWork W2030292497 @default.
• W2167234733 hasRelatedWork W2063867710 @default.
• W2167234733 hasRelatedWork W2087227024 @default.
• W2167234733 hasRelatedWork W2145841874 @default.
• W2167234733 hasRelatedWork W2158683245 @default.
• W2167234733 hasRelatedWork W2165433289 @default.
• W2167234733 hasRelatedWork W2167234733 @default.
• W2167234733 hasRelatedWork W2292125292 @default.
• W2167234733 hasVolume "201" @default.
• W2167234733 isParatext "false" @default.

• next