Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167239175> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2167239175 endingPage "299" @default.
- W2167239175 startingPage "293" @default.
- W2167239175 abstract "The dynamic relationship of glucose concentrations and insulin secretion during the postabsorptive state is complex and has been associated with a variety of cyclic rhythms. To study the pattern of insulin and glucose response immediately after a mixed meal, we collected blood every 15 min from 0730 to 1645 h from eight normal resting men (age 24.9 ± 2 . 1 yr). They took identically constituted mixed meals at 0800 and 1145 h. Concentrations of glucose and insulin were measured in samples taken throughout the study, whereas levels of C-peptide, glucagon, and a-NH2 were determined in samples taken after 1130 h only. Computer-assisted analysis was used to identify significant increments and declines in concentrations and to quantify the coincidence of peaks of glucose, C-peptide, glucagon, and α-NH2 with peaks of insulin. Coefficients of correlation between data points were calculated for each individual. The patterns of blood insulin and glucose after breakfast and lunch were different. After breakfast, a single simultaneous peak in insulin and glucose occurred ∼60 min after starting the meal. In contrast, the pattern after lunch in seven of the eight subjects was clearly biphasic. There were secondary, significant coincident peaks in serum insulin, glucose, and C-peptide occurring 1.75—2.25 h after the meal was served. The secondary peak appeared unrelated to the late absorption of protein because it was not associated with consistent changes in serum a-NH2 concentration. Erratic variations characterized the postlunch pattern of glucagon levels, excluding a role for this counterregulatory hormone in the control of the biphasic insulin and glucose response. Of the measured substances, only glucose, insulin, and C-peptide demonstrated significant cross-correlations. These data indicate that in this well-defined group of healthy volunteers, the response of plasma glucose, serum insulin, and C-peptide to lunch is biphasic." @default.
- W2167239175 created "2016-06-24" @default.
- W2167239175 creator A5000817850 @default.
- W2167239175 creator A5040133166 @default.
- W2167239175 creator A5053862190 @default.
- W2167239175 creator A5077822780 @default.
- W2167239175 date "1987-05-01" @default.
- W2167239175 modified "2023-09-26" @default.
- W2167239175 title "Biphasic Patterns of Peripheral Insulin and Glucose Levels After Lunch in Normal Subjects" @default.
- W2167239175 cites W2009754564 @default.
- W2167239175 cites W2013089541 @default.
- W2167239175 cites W2017873677 @default.
- W2167239175 cites W2032622596 @default.
- W2167239175 cites W2042267006 @default.
- W2167239175 cites W2051091678 @default.
- W2167239175 cites W2059247207 @default.
- W2167239175 cites W2071067131 @default.
- W2167239175 cites W2074739782 @default.
- W2167239175 cites W2075432529 @default.
- W2167239175 cites W2078407522 @default.
- W2167239175 cites W2078650670 @default.
- W2167239175 cites W2083327053 @default.
- W2167239175 cites W2120162658 @default.
- W2167239175 cites W2121653625 @default.
- W2167239175 cites W2135933721 @default.
- W2167239175 cites W2151425805 @default.
- W2167239175 cites W221284297 @default.
- W2167239175 cites W2317353168 @default.
- W2167239175 cites W2419533792 @default.
- W2167239175 cites W2422164086 @default.
- W2167239175 cites W2472200838 @default.
- W2167239175 cites W2493791194 @default.
- W2167239175 cites W313442901 @default.
- W2167239175 cites W414253344 @default.
- W2167239175 doi "https://doi.org/10.2337/diacare.10.3.293" @default.
- W2167239175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3297577" @default.
- W2167239175 hasPublicationYear "1987" @default.
- W2167239175 type Work @default.
- W2167239175 sameAs 2167239175 @default.
- W2167239175 citedByCount "11" @default.
- W2167239175 countsByYear W21672391752013 @default.
- W2167239175 countsByYear W21672391752018 @default.
- W2167239175 countsByYear W21672391752021 @default.
- W2167239175 countsByYear W21672391752022 @default.
- W2167239175 countsByYear W21672391752023 @default.
- W2167239175 crossrefType "journal-article" @default.
- W2167239175 hasAuthorship W2167239175A5000817850 @default.
- W2167239175 hasAuthorship W2167239175A5040133166 @default.
- W2167239175 hasAuthorship W2167239175A5053862190 @default.
- W2167239175 hasAuthorship W2167239175A5077822780 @default.
- W2167239175 hasConcept C126322002 @default.
- W2167239175 hasConcept C134018914 @default.
- W2167239175 hasConcept C2777391703 @default.
- W2167239175 hasConcept C2778345441 @default.
- W2167239175 hasConcept C2778563252 @default.
- W2167239175 hasConcept C2778875212 @default.
- W2167239175 hasConcept C2779306644 @default.
- W2167239175 hasConcept C2780352109 @default.
- W2167239175 hasConcept C3017594758 @default.
- W2167239175 hasConcept C3020574416 @default.
- W2167239175 hasConcept C555293320 @default.
- W2167239175 hasConcept C71315377 @default.
- W2167239175 hasConcept C71924100 @default.
- W2167239175 hasConceptScore W2167239175C126322002 @default.
- W2167239175 hasConceptScore W2167239175C134018914 @default.
- W2167239175 hasConceptScore W2167239175C2777391703 @default.
- W2167239175 hasConceptScore W2167239175C2778345441 @default.
- W2167239175 hasConceptScore W2167239175C2778563252 @default.
- W2167239175 hasConceptScore W2167239175C2778875212 @default.
- W2167239175 hasConceptScore W2167239175C2779306644 @default.
- W2167239175 hasConceptScore W2167239175C2780352109 @default.
- W2167239175 hasConceptScore W2167239175C3017594758 @default.
- W2167239175 hasConceptScore W2167239175C3020574416 @default.
- W2167239175 hasConceptScore W2167239175C555293320 @default.
- W2167239175 hasConceptScore W2167239175C71315377 @default.
- W2167239175 hasConceptScore W2167239175C71924100 @default.
- W2167239175 hasIssue "3" @default.
- W2167239175 hasLocation W21672391751 @default.
- W2167239175 hasLocation W21672391752 @default.
- W2167239175 hasOpenAccess W2167239175 @default.
- W2167239175 hasPrimaryLocation W21672391751 @default.
- W2167239175 hasRelatedWork W153346821 @default.
- W2167239175 hasRelatedWork W1981107935 @default.
- W2167239175 hasRelatedWork W1988703247 @default.
- W2167239175 hasRelatedWork W2000308085 @default.
- W2167239175 hasRelatedWork W2001349399 @default.
- W2167239175 hasRelatedWork W2039558760 @default.
- W2167239175 hasRelatedWork W2070076315 @default.
- W2167239175 hasRelatedWork W2136112043 @default.
- W2167239175 hasRelatedWork W2150391763 @default.
- W2167239175 hasRelatedWork W2472716180 @default.
- W2167239175 hasVolume "10" @default.
- W2167239175 isParatext "false" @default.
- W2167239175 isRetracted "false" @default.
- W2167239175 magId "2167239175" @default.
- W2167239175 workType "article" @default.