FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167257388> ?p ?o ?g. }

• W2167257388 endingPage "7067" @default.
• W2167257388 startingPage "7061" @default.
• W2167257388 abstract "Thyroid cancer 1 (TC1, C8orf4) plays important roles in many signaling pathways, such as Wnt/β-catenin signaling pathway, and is involved in the development of many cancers. The objective of this study was to examine the expression of TC1 and investigate the associations among TC1, β-catenin, Chibby, cyclin D1, and the clinicopathological factors of oral tongue squamous cell carcinomas (OTSCCs). The expressions of TC1, β-catenin, Chibby, and cyclin D1 were examined in 109 cases of OTSCCs using immunohistochemistry. The expression of TC1 was observed in all cases of OTSCCs but was negative or weak in normal squamous epithelial tissues of tongue. The high expression of TC1 was correlated with the advanced TNM stage (P = 0.042), the abnormal expression of β-catenin (correlation coefficient = 0.314, P = 0.001) and the expression of cyclin D1 (correlation coefficient = 0.274, P = 0.006) in OTSCCs. But we did not find any associations between TC1 and Chibby. The abnormal expression of β-catenin was correlated with the poor differentiation (P = 0.035), advanced TNM stage (P = 0.048) and the expression of cyclin D1 (correlation coefficient = 0.422, P < 0.001). In conclusion, the high expression of TC1 was common in OTSCCs and correlated with the expression of β-catenin and cyclin D1 and the progression of OTSCCs. The high expression level of TC1 might promote the progression of OTSCCs by enhancing the activity of Wnt signaling pathway." @default.
• W2167257388 created "2016-06-24" @default.
• W2167257388 creator A5004358315 @default.
• W2167257388 creator A5017774638 @default.
• W2167257388 creator A5023811312 @default.
• W2167257388 creator A5029360035 @default.
• W2167257388 creator A5031647838 @default.
• W2167257388 creator A5042727018 @default.
• W2167257388 creator A5052874326 @default.
• W2167257388 creator A5066716873 @default.
• W2167257388 creator A5073511506 @default.
• W2167257388 creator A5084194983 @default.
• W2167257388 date "2015-04-14" @default.
• W2167257388 modified "2023-10-06" @default.
• W2167257388 title "The high expression of TC1 (C8orf4) was correlated with the expression of β-catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue" @default.
• W2167257388 cites W1826797943 @default.
• W2167257388 cites W1967328956 @default.
• W2167257388 cites W1973977844 @default.
• W2167257388 cites W1977841877 @default.
• W2167257388 cites W1978506977 @default.
• W2167257388 cites W1982504559 @default.
• W2167257388 cites W1985222234 @default.
• W2167257388 cites W1987081041 @default.
• W2167257388 cites W1993525179 @default.
• W2167257388 cites W2003843680 @default.
• W2167257388 cites W2010608162 @default.
• W2167257388 cites W2032438201 @default.
• W2167257388 cites W2039520194 @default.
• W2167257388 cites W2041908152 @default.
• W2167257388 cites W2042440356 @default.
• W2167257388 cites W2045459429 @default.
• W2167257388 cites W2064411813 @default.
• W2167257388 cites W2069065842 @default.
• W2167257388 cites W2073494549 @default.
• W2167257388 cites W2092271761 @default.
• W2167257388 cites W2106787323 @default.
• W2167257388 cites W2114318388 @default.
• W2167257388 cites W2119540244 @default.
• W2167257388 cites W2123851275 @default.
• W2167257388 cites W2123943688 @default.
• W2167257388 cites W2125498005 @default.
• W2167257388 cites W2135293703 @default.
• W2167257388 cites W2161624949 @default.
• W2167257388 cites W2171636247 @default.
• W2167257388 cites W298121409 @default.
• W2167257388 doi "https://doi.org/10.1007/s13277-015-3423-1" @default.
• W2167257388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25869879" @default.
• W2167257388 hasPublicationYear "2015" @default.
• W2167257388 type Work @default.
• W2167257388 sameAs 2167257388 @default.
• W2167257388 citedByCount "13" @default.
• W2167257388 countsByYear W21672573882016 @default.
• W2167257388 countsByYear W21672573882017 @default.
• W2167257388 countsByYear W21672573882018 @default.
• W2167257388 countsByYear W21672573882019 @default.
• W2167257388 countsByYear W21672573882020 @default.
• W2167257388 countsByYear W21672573882022 @default.
• W2167257388 crossrefType "journal-article" @default.
• W2167257388 hasAuthorship W2167257388A5004358315 @default.
• W2167257388 hasAuthorship W2167257388A5017774638 @default.
• W2167257388 hasAuthorship W2167257388A5023811312 @default.
• W2167257388 hasAuthorship W2167257388A5029360035 @default.
• W2167257388 hasAuthorship W2167257388A5031647838 @default.
• W2167257388 hasAuthorship W2167257388A5042727018 @default.
• W2167257388 hasAuthorship W2167257388A5052874326 @default.
• W2167257388 hasAuthorship W2167257388A5066716873 @default.
• W2167257388 hasAuthorship W2167257388A5073511506 @default.
• W2167257388 hasAuthorship W2167257388A5084194983 @default.
• W2167257388 hasConcept C11882975 @default.
• W2167257388 hasConcept C120089663 @default.
• W2167257388 hasConcept C121608353 @default.
• W2167257388 hasConcept C126322002 @default.
• W2167257388 hasConcept C137620995 @default.
• W2167257388 hasConcept C142724271 @default.
• W2167257388 hasConcept C146357865 @default.
• W2167257388 hasConcept C151730666 @default.
• W2167257388 hasConcept C199835354 @default.
• W2167257388 hasConcept C204232928 @default.
• W2167257388 hasConcept C2779744641 @default.
• W2167257388 hasConcept C29537977 @default.
• W2167257388 hasConcept C30145163 @default.
• W2167257388 hasConcept C502942594 @default.
• W2167257388 hasConcept C62478195 @default.
• W2167257388 hasConcept C71924100 @default.
• W2167257388 hasConcept C86803240 @default.
• W2167257388 hasConcept C95444343 @default.
• W2167257388 hasConceptScore W2167257388C11882975 @default.
• W2167257388 hasConceptScore W2167257388C120089663 @default.
• W2167257388 hasConceptScore W2167257388C121608353 @default.
• W2167257388 hasConceptScore W2167257388C126322002 @default.
• W2167257388 hasConceptScore W2167257388C137620995 @default.
• W2167257388 hasConceptScore W2167257388C142724271 @default.
• W2167257388 hasConceptScore W2167257388C146357865 @default.
• W2167257388 hasConceptScore W2167257388C151730666 @default.
• W2167257388 hasConceptScore W2167257388C199835354 @default.
• W2167257388 hasConceptScore W2167257388C204232928 @default.
• W2167257388 hasConceptScore W2167257388C2779744641 @default.
• W2167257388 hasConceptScore W2167257388C29537977 @default.

• next