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- W2167329318 abstract "A moderate resolution single nucleotide polymorphism (SNP) map of the genome of Drosophila melanogaster that is designed for use in quantitative genetic mapping is described. Seventeen approximately 500 nucleotide gene sequences spaced at 10 to 20 centimorgan intervals were combined with 49 shorter sequence tag sites (STSs) at 5 to 10 centimorgan intervals to generate a map that should not leave any gaps greater than one half of a chromosome arm when any two wild type lines are compared. Of 20 markers with sufficient polymorphism to construct haplotype cladograms, 13 showed evidence for two divergent classes of haplotype. The possible mechanisms for and implications of the unexpected finding that two thirds of all short gene sequences in D. melanogaster may be dimorphic are discussed, including the suggestion that admixture between two separate lineages may have been a major event in the history of the species.J. Exp. Zool. (Mol. Dev. Evol.) 288:63–75, 2000. © 2000 Wiley-Liss, Inc." @default.
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- W2167329318 date "2000-04-15" @default.
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- W2167329318 title "Haplotype dimorphism in a SNP collection fromDrosophila melanogaster" @default.
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- W2167329318 doi "https://doi.org/10.1002/(sici)1097-010x(20000415)288:1<63::aid-jez7>3.0.co;2-1" @default.
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