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- W2167341802 startingPage "93" @default.
- W2167341802 abstract "Tradicionalmente las lesiones en el tejido oseo causadas por trauma, osteonecrosis y tumores han sido tratadas con el implante de injertos autologos, alogenicos o xenogenicos; en otros casos, implantando materiales sustitutivos. En vista de problemas como la escasez de donantes, la transmision de enfermedades, la morbilidad del sitio de extraccion y la incapacidad de los materiales para remodelarse y reaccionar ante condiciones fisiologicas, se hace necesaria la busqueda de soluciones donde la ingenieria de tejidos aparece como una opcion para restaurar, mantener o mejorar la funcion mediante la creacion de sustitutos biologicos que incluyan celulas cultivadas en matrices tridimensionales, en un medio de cultivo suplementado con factores de crecimiento. En este articulo se realiza una revision bibliografica de los conceptos basicos que abarca la ingenieria de tejido oseo. Abstract: Usually bone tissue loss caused by trauma, osteonecrosis, and tumors has been treated using autograft, allograft, xenograft, and implantation of substitute materials. Each of these treatments has significant limitations, like availability of sufficient donor tissue, disease transmission, donor site morbidity, and inability of materials to remodel and react against physiological conditions. For all these reasons there is a need for alternative bone replacement procedures. Tissue Engineering aims to satisfy this need by the development of bone substitutes using different cell types, three-dimensional matrixes (scaffolds), in a medium supplemented with growth factors. The present review is focused in Bone Tissue Engineering and its most important aspects." @default.
- W2167341802 created "2016-06-24" @default.
- W2167341802 creator A5029897480 @default.
- W2167341802 creator A5032465431 @default.
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- W2167341802 date "2006-06-01" @default.
- W2167341802 modified "2023-09-23" @default.
- W2167341802 title "INGENIERÍA DE TEJIDO ÓSEO: CONSIDERACIONES BÁSICAS" @default.
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- W2167341802 doi "https://doi.org/10.24050/reia.v3i5.150" @default.
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